Lyle Berkowitz
InvestorFounderGeneral Partner at 2Flo Ventures · Founder at KeyCare
Chicago, Illinois
Writes $100K – $5M checks · typically $1.5M
FoundedKeyCare
About
An active healthcare advisor and investor with over 25 years of experience as a primary care physician and health IT innovator.
Founder at KeyCare
Intro paths
→
In turn, Lyle can intro founders to KeyCare's investors below.
Board director at KeyCare
Intro paths
→
In turn, Lyle can intro founders to KeyCare's investors below.
KeyCare's investors · 6
Co-founders at KeyCare
Experience
- KeyCareFounder and Executive Chairmancurrent2021 — presentChicago, IL
- KeyCareChief Executive Officer2021 — 2025Chicago, Illinois, United States
- Back 9 Healthcare ConsultingFounder and CEOcurrent1996 — present
- Cobblestone Ventures, LLCManaging Directorcurrent2020 — present
- Szollosi Healthcare Innovation Program at Northwestern MedicineFounder and Executive Directorcurrent2007 — presentGreater Chicago Area
- Northwestern University - The Feinberg School of MedicineAssociate Professor of Clinical Medicinecurrent1995 — presentGreater Chicago Area
- Northwestern MedicinePhysician, Informaticist, Innovatorcurrent1995 — presentGreater Chicago Area
- Oneview HealthcareBoard Member2016 — 2023
- PatientBondBoard Member2021 — 2022
- Healthfinch by Health CatalystFounder and Chairman Of The Board2011 — 2020Madison, Wisconsin Area
- MDLIVE, Inc.Chief Medical Officer & EVP of Product Strategy2018 — 2020
- RiseHealthCo-Founder and Chief Medical Officer2009 — 2011
- ProxicomChief Medical Officer1999 — 2001
- ApolloHealthFounder and President1998 — 1999
- Advanced HealthChief Medical Officer1997 — 1998Chicago
Education
- Northwestern University
- Northwestern Memorial HospitalInternal Medicine Residency, Primary Care Track1992 — 1995
- University of PennsylvaniaBSE, Bioengineering and Biomedical Engineering1984 — 1988
- University of Illinois at Chicago College of MedicineMD1988 — 1992
- Harvard Medical SchoolMedical informatics sub-fellowship1991 — 1992
Skills & more
Strategy80Digital Health10Board of Directors25Healthcare Information Technology99Informatics99EHR99Healthcare99Hospitals99Healthcare Management99Medicine99Clinical Research99Healthcare Consulting98
+12 more
Healthcare IndustryHealthcare Information Technology (HIT)Start-upsManaged CareEntrepreneurshipPatient SafetyPublic HealthQuality ImprovementRevenue CycleEMRElectronic Medical Record (EMR)Epic SystemsFrom Lyle's professional profile.
Colleagues at 2Flo Ventures
Amanda Johnson
Venture Fellow at 2Flo Ventures
Amanda Waldhauser
Executive Director at Roivant Social Ventures at 2Flo Ventures
Angela James
Senior Advisor at 2Flo Ventures
Azurii Collier
Commercial Advisor at 2Flo Ventures
Brenda Ametepe
Venture Fellow at 2Flo Ventures
Charlotte Jones-Burton
Partner at 2Flo Ventures
Christina Broomes
Commercial Advisor at 2Flo Ventures
Christopher Whitfield
Strategic Advisor at 2Flo Ventures
Frequently asked questions
- Who is Lyle Berkowitz?
- An active healthcare advisor and investor with over 25 years of experience as a primary care physician and health IT innovator.
- Where does Lyle Berkowitz work?
- Lyle Berkowitz is Founder of KeyCare and General Partner at 2Flo Ventures.
- What check size does Lyle Berkowitz write?
- Lyle Berkowitz typically writes checks of $100K – $5M.
- What companies did Lyle Berkowitz found?
- Lyle Berkowitz founded KeyCare.
- Where did Lyle Berkowitz go to school?
- Lyle Berkowitz studied at Northwestern University; Northwestern Memorial Hospital (Internal Medicine Residency, Primary Care Track); University of Pennsylvania (BSE, Bioengineering and Biomedical Engineering).
Founder mafias
Y Combinator mafia8,773
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Sam AltmanPresidentFounded Tools for Humanity +3Jessica LivingstonCo-founderFounded Y CombinatorAlexis OhanianYC Summer 2005Founded RedditFred EhrsamYC Summer 2012Founded Nudge +1Matt HuangYC Winter 2011Founded HotspotsTrae StephensYC Winter 2022Founded Pursuit +1
+ 8,766 more
University of Pennsylvania mafia201
Also came through, then founded or led a company.
Kunal BahlSystems EngineeringFounded SnapdealScott Wolf, MDBAFounded Cardiac Dimensions +3Ben LererBSFounded Thrillist +1Eric HeilBSEFounded Ladderbio +1Trevor PriceB.A.Founded Quilted Health +1Hari SundramDoctor of Medicine (MD)Founded Write Wise +1
+ 194 more
Northwestern University mafia79
Also came through, then founded or led a company.
Sheridan ClayborneB.S (Dropped Out)Founded Lendtable +1Andy RinkGeneral Surgery Residency ProgramFounded Playgroundpediatrics +1Jeffrey LiuBachelor of Science - BSFounded Guavapass +1Colton DillionMSFounded Quip Network +1Danielle YoesepMaster of Science - MSFounded Hona +1Daanish KhaziBachelor of Arts (B.A.)Founded Paper Instruments +1
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Harvard Medical School mafia28
Also came through, then founded or led a company.
Sangeeta N. BhatiaDoctor of Medicine (MD)Founded Port Therapeutics +3Rushika FernandopulleM.D.Founded Iora HealthKevin BittermanPh.D.Founded Editas MedicineKush M ParmarMDFounded Homology MedicinesCarlos LoyaPhDFounded Aldebaran TherapeuticsJeffrey M. JonasMDFounded Sage Therapeutics
+ 21 more
University of Illinois Chicago mafia10
Also came through, then founded or led a company.
Anshul SadanaMSFounded NexthopPaul BurtonBAFounded Akan BiosciencesBetsy ForeBachelor of Fine Arts (BFA)Founded Tiny OrganicsDave MessinaBachelor of Science (BS)Founded Cofactor GenomicsVincent PribbleBachelor of Science - BSFounded Micro MeatSneh PatelFounded Delfino AI
+ 3 more
Same school
Also attended University of Pennsylvania768
Brian ActonCo-founder of WhatsApp; co-founder of Signal FoundationKunal BahlCo-founder of Snapdeal; co-founder of Titan CapitalDasha MaggioPartner at Felicis Ventures, writer on venture capital and founder psychologyNancy WangInvestor at Felicis VenturesLeah von SiemensPartner at Manta Ray VenturesEghosa OmoiguiFounder and Managing General Partner at EchoVC Partners
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Also attended University of Illinois at Chicago College of Medicine44
Sam BlackmanEntrepreneur in Residence at GV (Google Ventures)Kate WilschutzChief Financial Officer, Revolution Funds at RevolutionSteve ShafferOperating Partner at Volition CapitalAnshul SadanaCEO, Nexthop AI at EMERGENT VENTURESStefano GaliassoVice President at Energy Capital VenturesBoris GyllhamnInvestor at Almi Invest
+ 38 more
Also attended Harvard Medical School135
Niko BonatsosInvestment Team at General CatalystAnthony PhilippakisInvestor at GV (Google Ventures)Ben RobbinsInvestor at GV (Google Ventures)David ReshefInvestor at GV (Google Ventures)Krishna YeshwantInvestor at GV (Google Ventures)Morgan CheathamPartner and Head of Healthcare and Life Sciences at Breyer Capital
+ 129 more



















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