Wellness & Fitness Startups

Sayana is a mental wellness app that helps users manage stress, anxiety, and sleep through daily mood check-ins and personalized therapeutic practices. The app serves individual consumers and workplace teams globally.

2 investors

Seismic makes powered clothing that fuses apparel with robotics, using Flex-Drive electric muscles to provide core and hip support that reduces muscle strain and fatigue. Its products target worker safety (an over-the-clothes vest for jobs involving awkward postures) and wellness/mobility (supporting sit-to-stand movement and lumbar support for aging users).

2 investors

Sensai is a fitness and wellness platform that publishes health and training guidance for active people and athletes, including topics such as nutrition and heart health.

2 investors

Sequential Skin offers an end-to-end in vivo microbiome testing platform for evaluating skincare, scalp care, oral care, and intimate care products.

2 investors

Sequestr provides working capital financing to farmers, landowners, and project owners in climate-related sectors including renewable energy, sustainable agriculture, and forestry, while aligning with corporate environmental objectives. The distributed team develops financial services and zero-waste market solutions focused on climate mitigation projects.

2 investors

Seraphina Therapeutics develops food- and nature-based consumer health products, starting with the fatty acid C15:0 (pentadecanoic acid), aimed at replenishing micronutrients and metabolites that decline with age. The company focuses on evidence-based nutritional science for consumer wellness.

2 investors

Serenity Connect provides a voice-first platform with automated workflows and real-time communications designed for older adults and their care networks. It connects senior living, home health, hospice, and pharmacy providers with families through features like voice access to information, video calls, and e-forms.

2 investors

Sevelyn offers online access to licensed providers who share the Spanish language and Latino culture, connecting Latino clients with education and professional support at rates it states are a quarter of traditional prices. The service is delivered remotely through an encrypted platform focused on privacy and anonymity.

2 investors

ShapeScale is a home device that uses infrared depth sensors and a high-resolution camera to create a photorealistic 3D scan of a user's body, tracking measurements and body composition over time. Aimed at fitness-focused consumers, it provides visual before-and-after comparisons to show changes in muscle and fat.

2 investors

Sharecare operates a digital health platform that helps employees, health plan members, and patients manage their health, navigate care, and optimize benefits. Its offerings include health tracking, evidence-based digital therapeutics, personalized care navigation and advocacy, and in-home caregiving services via CareLinx.

2 investors

ShareWell offers online peer support groups, private 1-on-1 sessions with trained peer specialists, and skill-building workshops for people facing mental health and life challenges. It provides free live moderated group sessions across 150+ topics with paid membership options for unlimited groups and private support.

2 investors

Shimmer provides coaching, community, and digital tools designed specifically for people with ADHD, combining expert guidance with peer support to help them reach their potential. The platform serves neurodivergent individuals seeking ADHD-specific support outside traditional mental health systems.

2 investors

Felix Gray makes premium blue light filtering glasses with the filter embedded in the lens material, marketed to reduce eye strain, improve focus, and support sleep. Its consumer product line includes screen glasses, sleep glasses, and blue-light sunglasses sold direct to consumers.

2 investors

Silk + Sonder offers a subscription that combines a monthly guided journal-meets-planner with a companion app featuring how-to videos, coaching modules, meditations, and an online community. It uses techniques from therapy, coaching, and positive psychology to support self-care, habit formation, and mental and emotional well-being for individual consumers.

2 investors

SIQ (now Spalding TF DNA) develops smart basketballs equipped with sensor technology that track performance metrics. The product is designed for basketball players and coaches.

2 investors

Skillprint provides an AI platform and SDK that analyzes gameplay signals in real time to build cognitive and behavioral profiles of players, offering assessments for cognitive performance, learning, and mental wellness. It is aimed at game developers and platforms that want to add cognitive assessment, adaptive difficulty, and wellness insights to existing games.

2 investors

Skin Rocks is a skincare brand selling products such as moisturisers and serums (including a hyperpigmentation serum) directly to consumers, along with gift sets and refills. It also publishes an educational blog covering skincare routines and ingredient information.

2 investors

BrocStar sells a patented "super-broccoli" high in sulforaphane, offered as a once-weekly soup, a raw powder supplement, and dark chocolate-coated snacks aimed at supporting metabolic health. The consumer products target people focused on general wellness, specific health conditions, and athletes seeking recovery and performance benefits.

2 investors

SmartyPants makes vitamins and nutritional supplements formulated for kids and adults, including gummy multivitamins, sold direct-to-consumer and through retailers like Amazon. The company offers an auto-delivery subscription program and focuses on science-backed, good-tasting formulas.

2 investors

Sofie Pavitt Face is a skincare brand focused on acne-prone skin, selling products such as exfoliating scrubs, clearing serums, moisturizers, and sunscreen directly to consumers. Founded by celebrity aesthetician and acne specialist Sofie Pavitt, based in New York.

2 investors

Sofwave develops non-invasive, FDA-cleared ultrasound and electrical muscle stimulation (EMS) devices for improving skin laxity, lift, and tone by stimulating natural collagen, elastin, and hyaluronic acid production. Its aesthetic technology products also strengthen and tone muscles.

2 investors

Solta Medical develops and sells a portfolio of aesthetic skin treatment devices, including the Thermage line, used by medical and cosmetic practices to address common skin concerns such as skin tightening and contouring. It serves aesthetic practice providers who treat patients across a range of ages and skin types.

2 investors

Somethings is a mobile app that connects teens with Certified Peer Specialists who have overcome their own mental health challenges and provide chat and call support supervised by clinicians. It offers peer mentorship for issues such as depression, anxiety, and relationships, positioned as an alternative to therapy.

2 investors

SoulCycle offers indoor cycling fitness classes led by instructors with curated playlists, choreography, and coaching, along with a community around its studios. It targets consumers seeking group workout experiences.

2 investors