Wellness & Fitness Startups

Sibstar offers a debit card and companion app that lets people and their families set and remotely adjust spending, cashpoint, and location limits to protect against scams and overspending. It is aimed at people living with dementia, learning disabilities, mental health conditions, or in recovery, and the carers who support them, in the UK.

1 investor

Side by Side makes all-natural, whole-food dog food and treats — including freeze-dried diets, toppers, stews, and treats — formulated using Eastern Food Therapy to match each dog's individual nutritional needs. Products are made in small batches in the USA, with no synthetic or artificial additives, and the company offers a "Balance Indicator" tool that recommends recipes based on a photo of a dog's tongue.

1 investor

Sidekick develops digital therapeutics (DTx) programs for people with chronic conditions such as oncology, cardiovascular, metabolic, and inflammatory diseases, using gamification, behavioral psychology, and behavioral economics to improve health outcomes. Its Adaptive Care Paths combine multiple programs to support patients living with multiple chronic conditions.

1 investor

SIDIA is a fragrance brand that creates named scents based on emotional states rather than ingredients, positioning fragrances as extensions of personal identity. The company serves consumers seeking intimate, architecturally refined fragrances positioned as personal signatures.

1 investor

Siena on Brendenwood is a senior independent living retirement community offering housing and amenities for older adults. The community is owned and operated by First Midwest Group and provides services including duplex units and apartment-style living.

1 investor

Siga provides a scientific index and analysis tools that evaluate the degree of food processing and identify ultra-processed foods based on their ingredients. It serves agri-food industry players to help them build simpler, less-processed product offerings, with content also aimed at consumers.

1 investor

SignatureMD enables independent physicians to practice personalized, relationship-based medicine by handling administrative and operational aspects of their practices. The platform serves physicians seeking to maintain independence while delivering thoughtful patient care outside traditional healthcare systems.

1 investor

Sigrid Therapeutics develops non-pharmaceutical solutions for blood sugar control and weight management using its patented SiPore silica technology, which slows the digestion of carbohydrates and fats in the gut. The company offers medical and consumer metabolic health products aimed at people with prediabetes, diabetes, and obesity.

1 investor

SILK Laser operates skin clinics offering laser hair removal, skin treatments, cosmetic injectables, and non-invasive body sculpting, along with a clinical skincare product range. It serves beauty and skincare consumers across Australia.

1 investor

Silver Guardian is a digital platform for adults over 55 in Panama that enables health record management, social community connection, and job opportunities. The service operates as a web-based application without requiring app store downloads.

1 investor

Silverado Resort is a Napa Valley resort offering lodging, championship golf, dining, spa and wellness experiences, plus venues for weddings, meetings, and corporate events. It serves leisure and business travelers seeking accommodations and events in Napa, California.

1 investor

SIMO makes a daily multivitamin gummy for children ages 3–12 that combines 16 vitamins and minerals with a blend of 11 fruits and vegetables, formulated without added sugars, artificial sweeteners, or common allergens. The product is designed to support immune function, energy levels, cognitive development, and sleep quality through a subscription model with refillable glass bottles.

1 investor

SkinSmart makes FDA-cleared hypochlorous acid (HOCL) skin therapy sprays sold direct to consumers for eczema relief, blemish control, and daily skin hygiene. The antimicrobial products target problem bacteria to support the skin's natural healing process and are suitable for sensitive skin and all ages.

1 investor

Simply Go Natural makes organic hair care and skin care products, including a best-selling hair serum, using carefully selected ingredients with mostly non-water-based formulations to reduce preservatives. Its products are sold to consumers and stocked in retailers such as Sobeys in Ontario and Alberta, Canada.

1 investor

Sinewus positions itself around athletic training, recovery, and injury reduction, though the page provides only a tagline without concrete product details.

1 investor

SinuSauna is a wearable mask device that delivers heated dry air therapy to the nasal passages for congestion relief and germ reduction. It serves consumers seeking natural sinus and cold symptom management.

1 investor

SiO Beauty makes reusable medical-grade silicone patches that use compression and occlusion to smooth wrinkles and fine lines and hydrate the skin overnight on areas such as the forehead, eyes, chest, and lips. The products are direct-to-consumer skincare marketed as an alternative to injectables, lasers, and fillers.

1 investor

SIROBÈ is a natural, chemical-free skincare brand that makes products from botanical and farm-to-table ingredients such as fresh fruits and flowers to address targeted skin concerns. It emphasizes sustainability, ethical sourcing, and transparency for consumers seeking paraben-free skincare.

1 investor

SiSU Health operates self-service health check stations that measure cardiometabolic health metrics including blood pressure, BMI, body fat percentage, and diabetes risk for preventive health screening. The company supplies hardware stations to organizations and offers a digital platform to support personalized health improvement.

1 investor

Six Wing Studios is a game studio developing The Fog of Maya series and Amaru: The Self-care Virtual Pet, games designed to introduce players to mindfulness and meditation. It funds and delivers its titles and merchandise to fans through crowdfunding campaigns.

1 investor

Skavengerz develops an application designed to help people reduce time spent in digital environments and reconnect with the physical world. The company positions itself around facilitating a movement away from metaverse-focused lifestyles toward real-world engagement.

1 investor

Skin and Cancer Associates is a private dermatology group providing medical, cosmetic, and surgical dermatology care, including skin cancer diagnosis and Mohs surgery, across more than 30 locations in Florida. It serves patients seeking treatment for conditions such as skin cancer, acne, eczema, and psoriasis, as well as cosmetic procedures.

1 investor

Skin at Peace develops a skincare system that combines cleansing, balancing, protecting, and restoring steps formulated with barrier-support ingredients like ceramides and plant oils. The product is designed for consumers seeking gentle, non-irritating skincare.

1 investor

A charity providing on-site skin cancer screening services to Australian workplaces, combining employee health checks with data collection to inform national skin cancer prevention policy. The organization partners with medical practitioners to deliver full-body skin checks, digital lesion mapping, and follow-up referrals at corporate offices, job sites, and events.

1 investor