Longevity Startups

Aventi is a clinical-stage biopharmaceutical company developing therapeutics for sarcopenia, with plans to treat geriatric sarcopenia and expand to other age-related diseases. It operates in the biotechnology and pharmaceutical industry.

1 investor

Avid Health at Home provides in-home care services including personal care, companion care, respite care, private duty nursing, and specialized Alzheimer's/dementia and veteran care for aging adults and people with chronic or complex medical conditions. It serves communities across over 100 counties in North Carolina, Illinois, and Michigan.

1 investor

Aviv Clinics operates physician-led clinics offering a personalized hyperbaric oxygen therapy program (the Aviv Medical Program) aimed at improving cognitive and physical performance for people who are aging or recovering from chronic medical conditions. Its UHMS-accredited clinic is located in central Florida and its protocol is based on peer-reviewed hyperbaric medicine research.

1 investor

BE Therapeutics is an early-stage biotech company developing stem cell-derived replacement tissue to repair damage to the brain and spinal cord caused by stroke, trauma, neurodegeneration, and aging. It engineers precursor brain tissue and biomaterials such as its "PiaGel" for pre-clinical and clinical applications in central nervous system repair.

1 investor

Big Bold Health develops food-based nutritional supplements built on an "Immuno-Rejuvenation" approach that uses food compounds to support immune balance, longevity, and overall vitality. The company sells consumer wellness products such as HTB Rejuvenate sprout powder directly to individuals, with subscription options.

1 investor

BIOGENA develops premium micronutrient supplements, functional drinks, and longevity services for consumer health and wellness across different life stages. The company manufactures products in Austria focused on scientific efficacy, purity, and quality standards.

1 investor

Biomine Health is South Africa's microbiome testing and treatment company, providing personalized health insights based on microbiome analysis to help people understand and optimize their gut health. The company serves individuals seeking proactive health management through microbiome-based diagnostics and treatments.

1 investor

BioRestore is a healthcare clinic offering age-related and wellness treatments, including hormone/regenerative therapies and non-invasive pain treatments such as Bio Wave therapy, delivered by clinicians like nurse practitioners and physicians. It serves individual patients seeking evidence-based, patient-centric care, with a presence in New England.

1 investor

Birchgrove develops and rents purpose-built retirement apartments for people in later life, with all-inclusive monthly rent covering utilities, maintenance, 24-hour staffing, and communal amenities. Each neighbourhood offers on-site teams and access to wellbeing support and homecare partners, serving residents aged 65 and older across Surrey, Kent, and London.

1 investor

BOLD Longevity Growth is a global venture fund investing in growth-stage frontier biotechnologies at the intersection of longevity, biotech, and artificial intelligence that target the root causes of aging and age-related diseases. The fund co-invests with large biotech VC funds and pharmaceutical companies to help portfolio companies scale technologies aimed at extending the healthy human lifespan.

1 investor

Blue Longevity provides advanced diagnostics and evidence-based therapies, combining scientific research with personalized care to create individualized longevity plans for people focused on their long-term health.

1 investor

Bonus Biogroup is a clinical-stage biotechnology company developing tissue engineering and cell therapy products for unmet medical needs related to tissue damage, inflammation, and immune response. Its investigational products include MesenCure, an allogeneic cell therapy targeting inflammation, and BonoFill, a tissue-engineered bone graft for orthopedic and maxillofacial bone defects.

1 investor

Booster Therapeutics develops small-molecule medicines that directly activate the cell's 20S proteasome to restore protein quality-control and clear disease-causing proteins, using its structure-based DGRADX platform combining high-throughput screening, X-ray crystallography, and computational tools. The company is building a multi-disease pipeline initially focused on neurodegenerative diseases.

1 investor

Brite Trace is a healthcare technology company offering a caregiving platform and educational courses to help family and professional caregivers coordinate dementia and Alzheimer's care, track behaviors, organize care information, and access research-backed guidance. It serves caregivers, families, healthcare professionals, and senior care organizations.

1 investor

Buckeye Senior Care is a private duty, non-skilled home care company that helps seniors remain safely at home through personal care, light housekeeping, meal preparation, companionship, and medication reminders. It serves seniors and their families, accepting private pay and long-term insurance, and operates as a preferred provider for the VA and Greene County Council on Aging.

1 investor

Calico is a research and development company studying the biology of aging and translating those insights into potential medicines for age-related diseases. It combines basic research, computational biology and machine learning, and drug development to advance early- and clinical-stage compounds.

1 investor

Calocurb makes a prescription-free, plant-based appetite-suppressing capsule containing Amarasate, a New Zealand hop extract that activates the body's natural satiety hormones (GLP-1, CCK, PYY) to reduce hunger and support weight management. Sold direct to consumers, it is positioned as a natural supplement alternative or complement to injectable GLP-1 weight loss medications.

1 investor

Cellergy develops allogeneic mitochondrial transplantation therapy, producing GMP-grade purified mitochondria from human primary cells for intravenous, repeated administration. Its therapy targets systemic and degenerative conditions such as CNS disorders, muscle degeneration, and aging, and uses a machine-learning model to predict donor/recipient matching.

1 investor

Cellgym develops IHHT/IHT (intermittent hypoxia-hyperoxia) training devices that simulate altitude training by having users breathe alternating oxygen-poor and oxygen-rich air through a mask. Its Cellair product line (Home, Pro, Lounge, and the CE Class IIa medical device One) serves private users, doctors and therapists, longevity and wellness centers, and premium hotels, with manufacturing in Germany.

1 investor

Chi Longevity is a precision longevity medicine practice that maps an individual's biology using diagnostics to create proactive plans aimed at preserving physical, cognitive, and mental function. It serves individuals seeking to extend their healthspan through science-led interventions and ongoing support.

1 investor

CIRCE Scientific develops patented ingredient synergies and formulations focused on cellular and systemic resilience, working with clients to co-create products for supplements, functional foods, cosmetics, and animal care. It serves brands in the health, longevity, and dermocosmetics markets, with applications spanning UV/environmental protection, sports recovery, and veterinary use.

1 investor

Circulate Health provides therapeutic plasma exchange (TPE) as a turnkey clinical service that it delivers through partner clinics, supplying trained apheresis nurses, FDA-cleared equipment, standardized protocols, and operational support. The company positions TPE as a longevity and healthspan intervention, backed by a clinical trial showing reduced biological age markers.

1 investor

Cirrus Therapeutics is a biotech developing gene and cell therapies based on ocular immunology to treat dry age-related macular degeneration (AMD), including an AAV gene therapy to restore the IRAK-M immune regulator and a next-generation retinal pigment epithelium (RPE) cell therapy for advanced geographic atrophy. It serves patients with chronic blinding eye diseases and operates from Cambridge, Massachusetts and Singapore.

1 investor

Cosmica builds OrganAge™, a blood-based biomarker tool that scores biological aging across nine physiological systems, and an intervention engine that ranks foods, supplements, and activities by how they act on a person's aging-related genes. Aimed at individuals as well as clinics and platform partners, the company applies peer-reviewed aging research to longevity measurement and optimization.

1 investor