Longevity Startups

Rejuvenation develops proprietary mRNA and lipid nanoparticle technology to safely lengthen telomeres in human cells, targeting cellular aging and diseases caused by short telomeres including pulmonary fibrosis, liver disease, and bone marrow failure.

6 investors

Accent Therapeutics is a biotechnology company focused on discovering and developing small molecule drugs to improve health outcomes for cancer patients. It operates in oncology-focused drug discovery and development.

5 investors

Cellbricks Therapeutics is a preclinical biotech company developing implantable tissue grafts using proprietary bioprinting technology, biomaterials, and human cells for regenerative medicine applications. The company combines deep tech innovation to restore tissue function at clinical scale across multiple therapeutic programs.

5 investors

Centenara Labs is a longevity-focused drug discovery company that translates research on the biology of aging into therapies intended to improve healthy aging and extend lifespan. It works with a global team drawn from medical and scientific institutions to develop longevity drugs and related technologies.

5 investors

Curana Health provides on-site primary care and value-based care for senior housing residents, operating Accountable Care Organizations (ACOs) and Medicare Advantage Special Needs Plans. It partners with senior living and skilled nursing operators across the United States to deliver care to seniors in assisted living and similar communities.

5 investors

Elysium develops healthcare products focused on aging research and healthy aging rather than disease treatment. The company translates aging research into accessible solutions for individuals seeking to improve their long-term health outcomes.

5 investors

Eternal is a personalized health platform that combines wearable data, lab results, and AI coaching to deliver customized podcasts, daily texts, and in-person care for fitness, health, and longevity. The service integrates diagnostics, training, and professional medical oversight for consumers seeking comprehensive health optimization.

5 investors

Fountain Life is a private preventive health membership service that uses AI-guided diagnostics, physician-led interpretation, and restorative therapeutics to detect issues early and create personalized plans focused on healthspan and longevity. It offers members always-on access to an integrated care team and an AI medical expert platform (Zori), delivered through clinics located across the United States.

5 investors

General Control is developing programmable, multiplexed epigenetic editing therapies designed to control the expression of several genes at once. It targets complex diseases with many interacting phenotypes, such as Alzheimer's and sarcopenia.

5 investors

GlycanAge offers glycan-based biological age testing and insights to help individuals understand their health and aging rate through advanced diagnostics. The company serves consumers and medical professionals interested in personalized longevity and preventive healthcare.

5 investors

Humanity offers an enterprise employee wellness platform that uses biological age monitoring to help teams improve health and productivity. The solution targets employers seeking to reduce absenteeism and build a health-focused workplace culture.

5 investors

Immunis Biomedical develops multi-active biologics based on stem cell-derived secretomes — cell-free therapeutics containing proteins, lipids and growth factors — aimed at treating age-related and immune-related diseases. Its approach targets multiple biological pathways at once rather than a single protein or mechanism.

5 investors

Maximus is an online telehealth clinic offering clinically-validated, personalized prescription protocols and lab testing focused on health optimization ("performance medicine") for men and women, covering areas like testosterone optimization, medical weight loss, hair regrowth, and stress/sleep support. It conducts its own clinical research and develops proprietary formulations, delivering care nationwide without insurance.

5 investors

Maxwell Biosciences develops therapeutics aimed at treating infectious diseases. The company works with research and defense institutions on biodefense and antimicrobial-related work.

5 investors

Mederva Health provides healthcare data analysis and interpretation tools that help individuals understand their health information and take actionable steps toward longer, healthier lives, with a focus on accessibility for the general population.

5 investors

NRG Therapeutics is a biotech company developing small-molecule drugs targeting the mitochondrial permeability transition pore (mPTP) for neurodegenerative diseases such as ALS and Parkinson's. Its team combines pharma and biotech drug discovery expertise across neurology and neuroscience.

5 investors

Nucleus provides genetic testing and analysis for couples planning pregnancy, screening for over 200 hereditary diseases, traits, and health conditions. For those undergoing IVF, the company offers embryo selection guidance to reduce disease risk and optimize traits including eye color, height, and intelligence.

5 investors

ONTO Health provides personalized fertility, hormone, and longevity care for patients at various stages of reproductive health, combining evidence-based medicine with diagnostics and wellness therapies. The company offers technology-enabled, human-centered care led by reproductive specialists, serving individuals planning fertility, seeking treatment, or exploring preventive reproductive health options.

5 investors

Samsara Therapeutics develops small-molecule therapeutics that activate autophagy to slow the progression of age-related neurodegenerative diseases such as ALS, Parkinson's, and Charcot-Marie-Tooth disease. It runs an in-house phenotypic screening platform using patient-derived iPSCs to identify and validate autophagy activators for drug discovery.

5 investors

Viome offers at-home tests that analyze the gut and oral microbiome plus cellular blood samples using mRNA/metatranscriptomic sequencing, returning 70+ health scores (including biological age and inflammation) and personalized food and supplement recommendations. The direct-to-consumer service, analyzed in a CLIA-certified lab, is aimed at individuals seeking insights into digestion, metabolism, and overall wellness.

5 investors

Aardvark Therapeutics is a clinical-stage biopharmaceutical company developing small-molecule drugs that inhibit hunger to treat metabolic diseases. Its lead compound, ARD-101, is an oral investigational drug for hunger-associated rare diseases that activates bitter taste receptors in the gut to trigger satiety signals, with potential applications in hyperphagia and obesity.

4 investors

Adipo develops investigational therapeutics that promote weight loss by activating brown fat to increase energy expenditure, offering an alternative to appetite-suppressing drugs like GLP-1s. The company targets people seeking weight management solutions beyond diet and calorie restriction.

4 investors

Affini-T Therapeutics develops TCR-based immunotherapies aimed at treating solid tumors, using two complementary therapeutic modalities. The company operates in the biotech and cancer immunotherapy space.

4 investors

Altos Labs develops computational and scientific approaches to reverse disease through breakthrough medicines, operating research institutes focused on cell health, computation, and drug discovery.

4 investors