Healthtech Startups

Shift Labs develops DripAssist, an FDA-cleared infusion rate monitor that enables safe delivery of gravity IV medications in home and out-of-hospital settings. The platform remotely tracks medication infusion rates and provides data analytics for healthcare providers administering home infusion therapy.

3 investors

Shockwave Medical develops intravascular lithotripsy (IVL) catheter systems used to treat calcified cardiovascular disease, marketed to interventional cardiologists and vascular specialists. Its products are medical devices consisting of catheters paired with generators.

3 investors

GC Showa Yakuhin is a dental care company specializing in oral healthcare products and solutions. The company focuses on supporting patients and caregivers in an aging society by emphasizing the connection between oral health and overall wellness.

3 investors

Sigma Genetics makes devices that use magnetic fields to introduce DNA, RNA, and other charged molecules into cells, offering advantages over electroporation including reduced arcing, better scalability, and reduced invasiveness for in vivo applications. The technology targets cell therapies, cancer drug delivery, DNA vaccines, biopharmaceutical manufacturing, and cosmetics.

3 investors

Sika is a marketplace platform that allows consumers to purchase wellness and health products using pre-tax HSA/FSA funds. The platform features fitness equipment, nutrition products, skincare, supplements, and wellness technology from vetted third-party merchants.

3 investors

Sikka provides integrated software for dental practices that consolidates scheduling, insurance, payments, reviews, and reporting in a single platform while automating administrative workflows like recalls and claim management. The platform helps practices optimize operations, reduce days sales outstanding variance, and improve production and collections visibility.

3 investors

Silna offers a Care Readiness Platform that automates prior authorizations, insurance benefit checks, and ongoing insurance monitoring for healthcare providers. The AI-powered platform verifies patient coverage and authorization requirements upfront to speed up patient intake and payment.

3 investors

AMN Healthcare is a publicly traded healthcare staffing and workforce solutions company that supplies clinical and nonclinical professionals — including nursing, allied, international, leadership, and locum staff — on travel, temp-to-hire, per diem, and permanent bases. It serves healthcare client organizations and integrates with HRIS, IT, and EHR systems to source talent.

3 investors

SimCare provides AI-powered avatar-based simulation practice for counseling and mental health training programs. The platform offers 500+ virtual client scenarios to help students develop interpersonal, counseling, and diagnostic skills across psychology, psychiatry, clinical counseling, social work, and behavioral health disciplines.

3 investors

Simcha is a biotechnology company developing new cancer medicines based on immune biology research. It focuses on translating discoveries in immune biology into oncology drugs for patients with cancer.

3 investors

Simergent develops medical device systems for regulated healthcare markets, with expertise in peritoneal dialysis and infusion pump technologies. The company is led by engineers with FDA clearance experience and clinical advisory from nephrologists.

3 investors

SIQ (now Spalding TF DNA) develops smart basketballs equipped with sensor technology that track performance metrics. The product is designed for basketball players and coaches.

3 investors

Sirius Medical develops surgical devices for precise breast cancer tumor localization and removal. The company serves surgeons and radiologists globally, operating in over 350 centers across 27 countries.

3 investors

Sironax is a biopharmaceutical company focused on the discovery and development of therapies for neurodegenerative, inflammatory and immunological, metabolic, and rare diseases. Its research targets conditions affecting longevity, those requiring supportive care, and certain rare diseases.

3 investors

3 investors

SiteRx works to make clinical research more accessible by improving transparency and diversity in clinical trials, connecting patients with research opportunities for their medical conditions. The company focuses on bringing treatments to market more efficiently, with a stated interest in Alzheimer's disease research.

3 investors

Sixfold develops RNA delivery technology for the biotech industry. The company was founded by an oncologist and plant scientist and focuses on advancing RNA-based therapeutic approaches through proprietary delivery methods.

3 investors

Sleep Reset is a digital sleep clinic offering online treatment for insomnia and obstructive sleep apnea through cognitive behavioral therapy, at-home sleep testing, and clinician-guided care. The platform serves individuals struggling with chronic sleep issues and provides alternatives to traditional sleep labs and sleep medication.

3 investors

Sleepiz develops a contactless sleep monitoring device placed on a bedside table that analyzes sleep patterns and respiratory data for remote patient monitoring of sleep apnea and chronic respiratory diseases. The company serves healthcare providers and patients in Switzerland, Germany, and India.

3 investors

Jacobian develops AI-powered diagnostic reporting software for radiologists and pathologists, combining clinical documentation and speech recognition to enhance imaging workflows. The company serves healthcare providers seeking to improve diagnostic accuracy and reduce clinician burden.

3 investors

Smartlens develops wearable microfluidic devices and AI-powered platforms for remote monitoring and diagnosis of anterior segment eye diseases, particularly glaucoma. The company's flagship product, miLens, is a contact lens for continuous intraocular pressure monitoring.

3 investors

SmartPak is an online retailer of horse health care and equine products, selling fly sprays, supplements, tack, apparel, and blankets to horse owners, including a subscription AutoShip program (SmartPaks) for supplements. It operates in the equine ecommerce and pet/animal wellness category.

3 investors

SmartyPants makes vitamins and nutritional supplements formulated for kids and adults, including gummy multivitamins, sold direct-to-consumer and through retailers like Amazon. The company offers an auto-delivery subscription program and focuses on science-backed, good-tasting formulas.

3 investors

Kii Health provides employee health navigation services that guide workers through complex healthcare decisions by connecting them with appropriate professionals and care pathways to improve outcomes and reduce organizational risk.

3 investors