Hardware Startups

Caladan Bio develops high-throughput benchtop bioreactor hardware and software for laboratory bioprocessing, enabling faster experimentation and lower costs for biotech R&D teams. The company integrates bioreactor equipment with AI-driven process modeling software to support strain optimization and scale-up workflows.

5 investors

Calient manufactures 3D MEMS optical switches that reduce switching costs for data center operators and network service providers. The switches improve resource utilization and enable multi-layer network optimization.

5 investors

Capacitech makes modular C-Link supercapacitor systems that mount on walls, fences, or cable trays and install in days, offering an alternative to cabinet-based power quality equipment. Its plug-and-play systems serve data centers running AI workloads, utilities integrating renewables, and microgrids handling large commercial and industrial loads.

5 investors

Casimir develops technology to extract usable energy from the quantum vacuum through Casimir cavities, aiming to create a novel power source for applications including advanced propulsion and energy generation. The company applies quantum physics research to produce practical energy systems.

5 investors

Chipmetrics provides 3D metrology solutions using test chips and wafers for semiconductor process control, serving semiconductor manufacturers and material developers optimizing deposition processes and yields.

5 investors

Cipher Surgical develops the OpClear platform, a laparoscopic device that uses CO2 flow and on-demand saline lens washing to keep the endoscope lens clear during complex endoscopic and laparoscopic surgery. It is aimed at surgical teams to maintain continuous intra-abdominal vision, reduce scope removal events, and shorten operating times.

5 investors

Claros develops hardware and software for power delivery and management in data centers, aimed at increasing compute density and energy efficiency for AI applications. Its systems target data center operators and edge devices, in the power management and energy technology category.

5 investors

Clean Electric develops hardware and software solutions for energy storage systems, managing battery design, deployment, and lifecycle management to support the transition to renewable energy.

5 investors

Concha Labs makes Concha Sol, an FDA-cleared over-the-counter self-fitting hearing aid that uses patented technology to personalize a user's sound profile, with a focus on hearing speech in noisy environments. The devices are aimed at individuals with mild-to-moderate hearing loss and are set up at home.

5 investors

Conry Tech develops HVAC technologies focused on energy efficiency and sustainability in climate technology. The company builds on its founders' background in cooling systems such as modular chillers and Turbocor compressors.

5 investors

Contego Medical develops the Neuroguard IEP System, a 3-in-1 carotid stenting device combining a carotid stent, dilation balloon, and integrated embolic protection with a 40-micron filter to reduce stroke and cognitive impairment from microembolization. The company also produces peripheral vascular devices; Medtronic is now the sole U.S. distributor of the carotid product.

5 investors

Control4 develops a smart home and business automation platform that centralizes control of connected devices including lighting, audio, video, climate, security, and intercom systems. The platform integrates with over 25,000 third-party products and serves homeowners and businesses globally through a network of authorized integrators.

5 investors

Coop makes the Smart Coop, an automated backyard chicken coop with an AI system (EggsteinAI) that detects predators, dual 1080p live-streaming cameras, an automatic sunrise/sunset door, and app-based controls and alerts. It targets consumers and first-time chicken keepers who want to raise backyard chickens with minimal effort.

5 investors

CUDIS builds a smart wearable ring with AI-powered coaching for daily recovery, anti-aging, and wellness. The platform combines biometric data from the device with personalized guidance and community features for athletes and everyday users across 103 countries.

5 investors

Curio makes interactive toys that come to life as conversational characters for children. It operates in the consumer toys and hardware space, combining physical plush characters with AI-driven interaction.

5 investors

CurvaFix develops the CurvaFix Low Profile intramedullary nailing system, curved implants for surgical stabilization of pelvic fractures. The devices are used by orthopedic trauma surgeons and orthopedic oncologists and are FDA-cleared for use in the United States.

5 investors

CX2 builds AI-enabled hardware and software systems for detecting, disrupting, and destroying RF threats in military operations across multiple domains. The company serves defense organizations and warfighters operating in the electromagnetic spectrum.

5 investors

Daisy is a national brand for smart home and small business technology installation and ongoing service, covering smart shades, lighting, home theater, audio, and security systems. It operates through a franchise model partnering with custom integration companies to serve homeowners and business owners across the United States.

5 investors

Dalus provides a collaborative systems engineering platform for hardware development teams to model complexity, manage requirements, and preserve engineering knowledge using SysML v2. The platform offers requirements management, system architecture design, analysis & verification, and AI-powered capabilities for engineering teams in regulated industries.

5 investors

DeepReach runs a data-collection network where individuals ("Data Partners") wear a shipped device to record real-world operation data and get paid per accepted task. The captured data supports AI/machine-learning training use cases, with contributors operating across dozens of countries.

5 investors

Dejero develops connectivity solutions that combine multiple networks to enable reliable transmission for field operations and live reporting. The company serves media, broadcasting, and public safety organizations requiring dependable connectivity in challenging environments.

5 investors

DexMate develops physical AI technology, providing products intended to support the building of embodied AI and robotics systems.

5 investors

DISA Tech develops HPSA (high-pressure slurry ablation), a patented mineral liberation technology that separates and concentrates critical minerals using high-velocity slurry collisions to improve recovery while reducing energy use in mining operations. It offers a modular platform aimed at mining companies as an alternative to legacy grinding processes.

5 investors

Dispatch develops heat shields for spacecraft reentry and cargo return, enabling high-frequency satellite operations at lower cost. The company manufactures reentry technology to support the commercial space economy.

5 investors