Enterprise Software Startups

SightCall VISION is a video intelligence platform that enables service teams to resolve customer and field service issues remotely, automatically capture expertise into searchable knowledge, and extract operational insights to improve service performance. It serves customer service, field service, insurance, healthcare, and manufacturing organizations.

2 investors

SightLine provides data analytics and consulting services to colleges and universities for enrollment management, financial aid strategy, pricing optimization, and student retention. The company builds custom analytical models and forecasts tailored to individual institutions' specific data, goals, and student demographics.

2 investors

Sigma360 provides a unified platform for anti-money laundering investigations and entity risk screening, aggregating over 100 billion data points from global sources across 260+ jurisdictions. The platform serves compliance teams at financial institutions, payment processors, and e-commerce companies with real-time alerts, AI-powered entity summaries, and audit-ready case tracking.

2 investors

Sign on Tab develops digital document management software with legally binding digital signatures and biometric data capture, offering products such as digital templates, a virtual printer, cloud storage, and API integrations. A division of ITO Group serving over 220 business customers, its largest client base is in the healthcare sector, where it supports patient onboarding and data management.

2 investors

Signal Fusion provides AI-powered behavioral and voice analytics that convert human signals into predictive intelligence for safety, readiness, and performance monitoring in high-stakes industries. The platform identifies subtle human-state changes like stress and coordination drift to prevent accidents and improve operational integrity across maritime, transportation, construction, mining, manufacturing, healthcare, energy, and utilities sectors.

2 investors

Signant Health provides software platforms and clinical trial solutions for life sciences companies to manage patient-reported outcomes, evidence generation, and digital endpoints in drug development programs across multiple therapeutic areas.

2 investors

airSlate SignNow is a document management and e-signature platform that enables teams to collaborate on document workflows with real-time updates, role-based permissions, and advanced security controls. The platform integrates with business tools like CRM systems, cloud storage, and project management applications to streamline document processes for organizations of all sizes.

2 investors

Siit builds a service desk platform that centralizes tools and information for teams, enabling leaders to make data-driven decisions, managers to automate workflows, and employees to have a personalized experience.

2 investors

Silatha is a consulting and platform company that builds inclusive workplaces by addressing unconscious biases, psychological safety, and diversity across organizational cultures. It offers consulting services, coaching programs, and behavioral research to help teams and leaders foster equitable, high-performing environments.

2 investors

Silk provides a software-defined storage area network (SAN) that accelerates cloud applications by optimizing I/O performance and data access. The platform targets enterprises in finance, healthcare, and SaaS that need consistent performance and cost efficiency in cloud-native environments.

2 investors

SilkPLM provides an AI-powered product description generator and product lifecycle management platform for e-commerce retailers. The platform enables teams to manage products and suppliers, collaborate on collections, run cost simulations, and generate SEO-optimized product descriptions in a single workspace.

2 investors

Rival provides AI-powered orchestration tools for HR functions including sourcing, recruiting, onboarding, and employee journey management. The platform integrates with existing ATS and HCM systems to streamline hiring and employee workflows for enterprise organizations.

2 investors

SilverSky provides managed security services, MxDR (managed detection and response), and cybersecurity consulting for regulated and audit-driven organizations, helping them operate security controls behind compliance frameworks such as HIPAA, PCI, CMMC, SOC 2, and ISO 27001. It serves industries including healthcare, financial services, retail, government, and education, working across existing tools and Microsoft environments.

2 investors

SilverSky provides cybersecurity advisory, managed security, and extended detection and response (XDR/MxDR) services for regulated and audit-driven organizations that cannot tolerate security failures. The company helps customers move from fragmented security activities to coordinated security execution through people, processes, and operational discipline.

2 investors

Simantic develops hardware simulation software that enables engineers and AI systems to test and debug embedded firmware without physical hardware constraints.

2 investors

Simartis develops mobile connectivity software for telecom operators, including OTA SIM management, eSIM, device management, SIM backup, and digital marketing platforms. Its solutions serve mobile network operators worldwide to manage SIM and device lifecycles and run subscriber engagement campaigns.

2 investors

Simeio develops Identity and Access Management (IAM) solutions for securing organizational access and identity systems.

2 investors

Simfuni provides a unified operating platform for life insurance companies that consolidates policy management, customer servicing, underwriting, claims, and payments into a single connected system. The platform is designed for modern life insurers seeking to improve operational efficiency, reduce system fragmentation, and enhance customer experiences throughout the policy lifecycle.

2 investors

Simperium builds a platform for syncing content across people and their devices, and released Simplenote as a showcase of the technology. The company was part of Y Combinator and has since been acquired.

2 investors

SimpleRose is a high-performance computing optimization company developing Rose, a parallel optimization engine for solving large-scale mixed-integer programming (MIP) problems. It parallelizes the entire solving process—branching, cuts, and heuristics—across CPUs and GPUs to give enterprises faster solve times on larger, more complex optimization problems.

2 investors

Simpleway builds unified communication and paging systems that consolidate fragmented infrastructure into a single control platform for airports, transit facilities, hospitals, schools, and corporate venues. It also develops audio hardware and serves critical-infrastructure operators worldwide.

2 investors

Simpli operates a platform that enables enterprises to redirect excess inventory and unsold products to nonprofits and charities instead of destroying them. The company serves large enterprises seeking to reduce waste while supporting communities in need.

2 investors

Simr (formerly UberCloud) provides a cloud platform for engineering simulation, using SimOps practices and high-fidelity digital twins to make simulation workloads more accessible for engineering and IT teams. The company serves engineering organizations running simulation-driven design and offers global collaboration through cloud enablement.

2 investors

Altair leverages high-performance computing and data science to solve complex engineering and scientific challenges for customers across industries. The company was acquired by Siemens, the leading industrial software company.

2 investors