Enterprise Software Startups

SightCall VISION is a video intelligence platform that enables service teams to resolve customer and field service issues remotely, automatically capture expertise into searchable knowledge, and extract operational insights to improve service performance. It serves customer service, field service, insurance, healthcare, and manufacturing organizations.

2 investors

SightLine provides data analytics and consulting services to colleges and universities for enrollment management, financial aid strategy, pricing optimization, and student retention. The company builds custom analytical models and forecasts tailored to individual institutions' specific data, goals, and student demographics.

2 investors

Sigma Computing provides a warehouse-native analytics platform that lets business teams build, deploy, and govern AI applications on live data warehouse data without moving it, using spreadsheet-style input tables, embedded agents, and automated actions. It serves enterprise data, finance, and operations teams building self-service dashboards and workflow apps.

2 investors

Sigma360 provides a unified platform for anti-money laundering investigations and entity risk screening, aggregating over 100 billion data points from global sources across 260+ jurisdictions. The platform serves compliance teams at financial institutions, payment processors, and e-commerce companies with real-time alerts, AI-powered entity summaries, and audit-ready case tracking.

2 investors

SigmanticAI provides an AI platform for semiconductor teams to automate hardware verification and RTL development using specialized agents that understand design code, run EDA tools, and manage coverage across the design workflow.

2 investors

Sign on Tab develops digital document management software with legally binding digital signatures and biometric data capture, offering products such as digital templates, a virtual printer, cloud storage, and API integrations. A division of ITO Group serving over 220 business customers, its largest client base is in the healthcare sector, where it supports patient onboarding and data management.

2 investors

Signal Fusion provides AI-powered behavioral and voice analytics that convert human signals into predictive intelligence for safety, readiness, and performance monitoring in high-stakes industries. The platform identifies subtle human-state changes like stress and coordination drift to prevent accidents and improve operational integrity across maritime, transportation, construction, mining, manufacturing, healthcare, energy, and utilities sectors.

2 investors

Signant Health provides software platforms and clinical trial solutions for life sciences companies to manage patient-reported outcomes, evidence generation, and digital endpoints in drug development programs across multiple therapeutic areas.

2 investors

SigNoz provides observability and monitoring tools that help DevOps engineers and developers reduce noise and extract actionable signals from their systems. The platform serves engineering teams working with microservices and distributed systems.

2 investors

Silatha is a consulting and platform company that builds inclusive workplaces by addressing unconscious biases, psychological safety, and diversity across organizational cultures. It offers consulting services, coaching programs, and behavioral research to help teams and leaders foster equitable, high-performing environments.

2 investors

SilkPLM provides an AI-powered product description generator and product lifecycle management platform for e-commerce retailers. The platform enables teams to manage products and suppliers, collaborate on collections, run cost simulations, and generate SEO-optimized product descriptions in a single workspace.

2 investors

RSA provides an AI-powered unified identity platform for organizations to manage authentication, access control, identity governance, and lifecycle management. The platform helps secure remote and hybrid work environments while maintaining compliance and reducing cybersecurity risks.

2 investors

SilverSky provides managed security services, MxDR (managed detection and response), and cybersecurity consulting for regulated and audit-driven organizations, helping them operate security controls behind compliance frameworks such as HIPAA, PCI, CMMC, SOC 2, and ISO 27001. It serves industries including healthcare, financial services, retail, government, and education, working across existing tools and Microsoft environments.

2 investors

Sim is an open-source AI workspace where teams build, deploy, and manage AI agents across their existing tool stack using 1,000+ integrations and every major LLM. The platform enables automation of real work through visual, conversational, or code-based interfaces for technical teams.

2 investors

SIMBA Chain provides a blockchain-based connected data fabric for enterprise and government supply chains, integrating public, internal, and OEM data to improve traceability, predict disruptions, and support regulatory compliance. It serves defense and manufacturing customers, including the U.S. Air Force and battery manufacturers, and enables EU Digital Product Passport compliance.

2 investors

Simeio develops Identity and Access Management (IAM) solutions for securing organizational access and identity systems.

2 investors

Simfuni provides a unified operating platform for life insurance companies that consolidates policy management, customer servicing, underwriting, claims, and payments into a single connected system. The platform is designed for modern life insurers seeking to improve operational efficiency, reduce system fragmentation, and enhance customer experiences throughout the policy lifecycle.

2 investors

Simple AI builds AI agents for revenue teams that automate customer interactions across voice, text, chat, and email channels. The agents perform sales and support tasks like booking appointments, following up on leads, handling objections, and personalizing recommendations to close deals.

2 investors

Simplee was a healthcare financial technology company that provided a patient financial engagement platform, helping hospitals and health systems offer transparent billing, estimates, and payment experiences. Acquired by Flywire in 2020.

2 investors

SimpleRose is a high-performance computing optimization company developing Rose, a parallel optimization engine for solving large-scale mixed-integer programming (MIP) problems. It parallelizes the entire solving process—branching, cuts, and heuristics—across CPUs and GPUs to give enterprises faster solve times on larger, more complex optimization problems.

2 investors

Simpleway builds unified communication and paging systems that consolidate fragmented infrastructure into a single control platform for airports, transit facilities, hospitals, schools, and corporate venues. It also develops audio hardware and serves critical-infrastructure operators worldwide.

2 investors

SimpliField (now part of YOOBIC) offers a mobile platform for retail operations that connects headquarters with in-store frontline teams through employee communication, task management, store visit workflows, onboarding/microlearning, and reporting analytics. It serves retail brands and franchises seeking to coordinate field teams and improve store execution.

2 investors

Simplifyd provides a cloud platform for deploying applications built by African teams, with no upfront infrastructure setup required. The service offers managed databases, file storage, and zero-rated mobile data access for end-users in emerging markets.

2 investors

SimplyAgree provides software that automates the creation and management of signature packets for legal teams, replacing manual assembly workflows with a platform that handles document customization, eSignature tracking, and compiled execution.

2 investors