Digital Health Startups

Optivio is developing a biofeedback-based SaaS platform, preparing for launch with its first customers. The company operates in the life science and digital health space.

1 investor

Optum provides integrated healthcare services including doctor visits, mental health care, specialty care, and wellness services delivered through clinics, home, and online channels. The company also offers tools and technology to healthcare payers and providers to improve care efficiency, reduce costs, and support preventive care for over 120 million people across the U.S.

1 investor

Opyn provides a healthcare technology platform that unifies benefits, care navigation, virtual care, price transparency, provider intelligence, and service automation for health plan members, providers, and the administrative teams that support them. It aims to help members make informed care decisions while reducing manual work and costs for the teams operating health plans.

1 investor

OpZira develops wearable and diagnostic testing systems for the detection and monitoring of retinal and visual pathway diseases. The company serves eye care professionals and healthcare providers working with patients at risk for or diagnosed with ocular conditions.

1 investor

Oralome is a direct-to-consumer education platform focused on chronic bad breath (oral malodor) and the oral microbiome, offering guided self-assessments, educational content, and clinician-ready summaries to help users prepare conversations with their dentist or doctor. It targets adults, particularly working professionals affected by chronic oral odor, and is non-diagnostic, performing no tests itself.

1 investor

OraMetrix develops SureSmile, an orthodontic treatment system that uses digital scanning and personalized treatment plans to produce clear aligners and other teeth-straightening appliances. It serves dental and orthodontic practices, with doctors prescribing and delivering the treatment to patients.

1 investor

OraQ is an AI clinical decision support system for dental practices that applies risk intelligence to standardize exams, flag clinical risk early and support treatment planning. Based in Calgary, it works with dental practices across North America.

1 investor

Orb Health provides "Care Management as a Service," using remote, EMR-connected virtual contact centers staffed with licensed administrative and clinical agents to handle patient access, scheduling, and care coordination on behalf of providers. It serves health centers, hospitals, health systems, and unions across fee-for-service, capitated, and value-based care models.

1 investor

ORCHA provides digital health assurance and assessment services, validating health technologies against global standards for suppliers, health systems, and regulators worldwide.

1 investor

Orchestra Health provides software for streamlining preoperative care processes, helping surgical facilities reduce cancellations and improve patient outcomes. The platform serves surgeon offices and health systems performing orthopedic and spine procedures.

1 investor

Ordinary Folk operates digital health brands noah and zoey, combining software, licensed doctors and pharmacists, and a delivery network to provide personalized telehealth care and medication delivery. It serves consumers across Singapore, Hong Kong, and Japan.

1 investor

Orfeostory is a web and mobile app development agency in Singapore that provides custom website design, development, and app creation services for businesses of various sizes. The company serves SMEs and corporate clients seeking web solutions ranging from e-commerce platforms to WordPress and PHP development.

1 investor

Organo-ID develops iPSC-derived organoid systems, including 3D hepatocyte models, to test drugs in better-modeled biological systems for predictive diagnostics and personalized therapies. The company serves drug development and treatment applications in oncology and rare disease, operating from Turkey with a global focus.

1 investor

Oriente is a fintech company providing mobile-first financial infrastructure and identity-based solutions for underserved consumers, small businesses, and merchants across Asia's fastest-growing economies. The company combines proprietary technology with partnerships to enable financial access and economic opportunity in emerging markets.

1 investor

Origin Medical develops a real-time AI assistant for prenatal ultrasound examinations that aims to shorten exam times, standardize workflows, and reduce errors. It serves sonographers, reading physicians, health systems, and private practices to improve the quality and consistency of prenatal scans and patient care.

1 investor

Origin provides in-home pediatric speech, occupational, and physical therapy by matching families with local licensed therapists who visit the child's home, with sessions covered by insurance. It also serves as a marketplace for therapists to set their own schedules and build caseloads by choosing clients in their area.

1 investor

ORII develops a screen-free smartphone accessory that allows users to interact with their phones through voice and touch without relying on a display. Designed for accessibility, the device serves users who need or prefer screen-free alternatives to traditional touchscreen devices.

1 investor

Orion Health builds a unified healthcare platform combining digital front-end and care record systems, serving healthcare providers and systems to improve care efficiency and patient outcomes through data insights and machine learning.

1 investor

Orreco provides an AI-driven decision-support platform for professional and elite sports teams, combining Bayesian statistical models and computer vision across modules for biomarkers, injury risk, recovery, wellness and women's performance. It serves staff and athletes with personalized ranges and an athlete app to guide recovery, readiness and performance decisions.

1 investor

Orreco combines AI with sports science to turn athlete data — including blood biomarkers, menstrual cycle tracking, and injury prediction — into actionable recovery and performance recommendations for elite athletes, pro teams, coaches, and doctors. Its products include Orreco.AI, FitrWoman, FitrCoach, and biomarker analytics platforms used across leagues such as the NBA, NFL, MLB, NHL, EPL, F1, and PGA Tour.

1 investor

Ortho BioMed combines expertise in medicine, engineering, and data science to develop medical technology solutions that improve patient outcomes.

1 investor

OrthoLoneStar is a management services organization (MSO) that oversees and supports the operations of individual orthopedic practices. It is led by executive and divisional leadership teams.

1 investor

ORX offers a Knowledge Base Intelligence (KBI) platform that ingests unstructured data such as transcripts, documents, and images and restructures it into AI-ready, SOP-aligned content to power AI copilots and chatbots in CCaaS, CRM, and EHR systems. It targets contact centers and health systems, integrating with platforms like Genesys, Five9, NICE, Zendesk, Talkdesk, Twilio, and Salesforce, with a focus on healthcare patient access and support.

1 investor

Oryx offers a tablet-based visual training program built on perceptual learning and neuroplasticity that trains the brain to process near-vision input more efficiently, aiming to reduce or eliminate dependence on reading glasses. It targets adults over 40 experiencing age-related decline in near vision and works through daily adaptive sessions delivered via an iPad or Android app.

1 investor