Digital Health Startups

Two Pore Guys is a diagnostics company developing a handheld nanopore-based analyte sensor for point-of-care testing, with applications including liquid biopsy cancer detection. It combines nanopore technology, biochemistry, and analytics to detect target sequences and other analytes.

1 investor

OnTracx offers a platform that applies recent scientific research to support the rehabilitation of runners with overuse injuries, measuring the actual load of each step and generating individualized return-to-run plans with remote field follow-up. It is aimed at healthcare professionals and clinics seeking to integrate running-injury rehabilitation into their existing practice.

1 investor

Oona Health is a health insurance provider that offers medical counselling, timely treatment and prevention to improve customers' quality of life and ability to work. It serves companies and their employees, and operates alongside a treatment-provider network and a digital health offering.

1 investor

OnTop-Health provides an integration layer that connects third-party applications to electronic health record (EHR) systems, automatically triggering the relevant app at the right point in a clinical workflow and moving data securely between the EHR and apps. It targets EHR vendors and healthcare providers, offering a white-label app marketplace with HIPAA-compliant cloud or local deployment.

1 investor

Open Arms is a nonprofit that provides free perinatal services—including prenatal education, continuous doula support during labor, lactation guidance, support groups, and home visits—for new and expecting parents from pregnancy through a child's second birthday. It also offers community resources, birth worker training, and a directory of local birth workers.

1 investor

OpenHealth provides a Lab Data API that harmonizes fragmented, heterogeneous lab results into a structured set of biomarkers and enriches them with medical context. It also offers modular white-label digital health reports and health wallets for patients and healthcare professionals in the health industry.

1 investor

OpenClinica eConsent is a digital consent platform for clinical trials that enables participants to review and electronically sign informed consent forms using media-rich content on any device. It serves academic researchers, sponsors, contract research organizations (CROs), and clinical trial sites who need to streamline enrollment while maintaining regulatory compliance across decentralized, hybrid, and in-person studies.

1 investor

OpenCoreEMR develops flexible, intuitive electronic medical records software for healthcare providers to manage patient care with reduced administrative friction. The platform addresses shortcomings in legacy EMR systems by streamlining clinical workflows and improving data accessibility.

1 investor

OpenDR provides an AI-powered scheduling platform for radiology and medical imaging practices, letting patients self-schedule complex exams such as MRI, CT, and mammography online, by phone, or via a 24/7 AI agent. It integrates with practices' existing RIS systems to apply clinical rules, exam-specific logic, and automated reminders to reduce no-shows and manual data entry.

1 investor

Open Health Technologies offers an API-based platform that harmonizes fragmented laboratory data into a standardized structure of biomarkers and enriches it with medical context. It serves patients, healthcare professionals, and businesses in the health industry, and provides white-label digital health reports and health wallets.

1 investor

OpenSalud (openhealth) provides workplace health and wellbeing programs, including an employee assistance program, personalized health evaluations, and a healthy-living app with access to doctors, psychologists, nutritionists, and trainers. It serves companies and individual users, focusing on physical health, mental and emotional wellbeing, and healthy habits across Europe and Latin America.

1 investor

A developer of patient simulation platforms and healthcare training solutions for hospitals, medical schools, first responders, and military personnel seeking hands-on surgical and emergency medical education.

1 investor

OPExPARK uses IoT technology to digitize operating rooms and standardize surgical practices globally. The company provides platforms for real-time surgical data integration, digital surgical education, and smart recording solutions for surgeons and medical institutions.

1 investor

OpiAID offers an AI-powered recovery intelligence platform that combines EHR data with biometric data from commercial wrist-worn wearables and applies machine learning to quantify withdrawal symptoms and support clinical decision-making. It serves clinicians and clinics treating Opioid Use Disorder (MOUD/MAT), providing dashboards, alerts, and remote monitoring to improve patient retention and care.

1 investor

Opkit offers AI-powered telephone agents that handle administrative tasks like patient intake, benefits verification, and scheduling for medical practices and telehealth providers. The service is built to HIPAA and SOC 2 specifications.

1 investor

OPKO Health is a fully integrated healthcare company developing multispecific therapies for serious diseases including cancers and infectious diseases, and operates BioReference Laboratories, a clinical reference laboratory serving approximately 11 million patients annually in the U.S.

1 investor

OPN Healthcare (Oncology Physicians Network) is a technology-enabled specialty healthcare services company and Management Services Organization focused on cancer care. It coordinates between payers/risk-holders and oncologists to support value-based community oncology care across US regions.

1 investor

OpSens Medical develops sensor-guided medical devices, including fiber optic guidewires and hemodynamic monitoring systems, for use in interventional cardiology procedures.

1 investor

Optegra operates dedicated private eye hospitals offering ophthalmic diagnostics, cataract and laser eye surgery, and aftercare delivered by NHS-trained consultant surgeons. It serves private and NHS eye-care patients, providing free video or telephone consultations and personalised treatment plans.

1 investor

OptiChroniX is a Swiss digital health company whose Rejuvify system provides a daily prioritization framework to preserve functional muscle and lean mass during weight loss, aging, and lifestyle changes. It uses real-world data such as body composition, activity, and behavior to focus users each day on protein intake, resistance stimulus, or recovery.

1 investor

Optimal offers an annual health checkup subscription that includes over 300 lab tests, two sample collections per year, and a medical consultation, with easy-to-read results and a personalized care plan. The service is sold directly to consumers for a yearly fee.

1 investor

Optimedis brings together interprofessional expertise from healthcare, economics, medicine, nursing, IT, and sociology to develop innovative healthcare delivery models and networks. The company appears to focus on building healthcare networks and developing care solutions for the German healthcare system.

1 investor

Optina develops a retinal imaging and AI platform for diagnosing and managing Age-Related Macular Degeneration in eye care specialists and patients. The platform combines hyperspectral imaging technology with AI clinical decision support to improve early detection and disease monitoring.

1 investor

Optina develops a retinal imaging and AI platform, combining an FDA 510(k) cleared hyperspectral camera with AI to help eye specialists diagnose and manage Age-Related Macular Degeneration and other retinal disease. The platform supports early, intermediate, and late-stage detection, risk monitoring, and tracking of therapeutic effectiveness in at-risk patients.

1 investor