Deep Tech Startups

Aclid provides an automation platform for biosecurity and biosafety compliance, offering real-time screening that generates threat assessments and risk profiles for genes, libraries, pools, viral vectors, and plasmids. It also automates verification of licenses, registrations, biosafety guidelines, and legitimate use for research organizations.

3 investors

Acoustica.bio develops acoustophoretic technology and microgel suspension formulations that concentrate biologic drugs (such as monoclonal antibodies) to ultra-high concentrations exceeding 500 mg/mL for small-volume subcutaneous injection. It serves drug developers, aiming to convert hospital-based intravenous therapies into patient-friendly at-home injections in the biotech/drug delivery space.

3 investors

Actio is a precision medicine company that translates genetic insights into new therapeutics, developing drugs that target the genes underlying both rare diseases and more prevalent conditions. It focuses on identifying dysregulated gene activity and designing therapies to restore balance and address the root causes of disease.

3 investors

Adden Energy develops solid-state, dynamically-stable batteries based on self-healing separator technology discovered at Harvard, aimed at fast charging, long lifetime, and non-flammable components. The batteries target electric vehicles, automakers, and other applications including drones, data centers, and robotics.

3 investors

Addimmune develops gene therapy treatments for HIV, specifically AGT103-T, a first-in-class functional cure candidate that modifies patient immune cells to recognize and eliminate HIV-infected cells. The company is based in Rockville, Maryland and targets individuals living with HIV.

3 investors

Aegiq develops networked photonic quantum systems, including a quantum computer and photon sources, intended for practical large-scale deployment. Its offerings span quantum computing hardware, optical fibre security, and software tooling for building and running quantum workflows.

3 investors

Aerial.ai uses AI and existing wireless infrastructure to create sensing technology, which it calls Sensing Intelligence, for smart applications. The company is built by a team of research scientists and engineers.

3 investors

Aerogen Systems develops point-of-use contamination control for semiconductor manufacturing, using a modular reactor that chemically destroys airborne molecular contamination where wafers sit exposed. Its systems aim to reduce yield loss and ultra-high-purity nitrogen purge costs for fabs, with a longer-term goal of eliminating the need for cleanrooms.

3 investors

Aerolane develops aerotowing technology that lets cargo aircraft fly in formation—pairing powered aircraft or towing engineless gliders—to extend range, increase payload, and lower operating costs. Its systems target the regional air freight market and are designed as retrofit upgrades for existing airframes.

3 investors

Aeronext is a Japanese technology startup developing drone technology aimed at building new social infrastructure in low-altitude airspace (up to 150 meters), with a focus on safety and using drones as a labor force to address population decline. It works to create an economy around three-dimensional airspace and partners with domestic and international collaborators.

3 investors

AEXLAB builds virtual reality technology for gaming, training, and simulation, aiming to make users feel present and connected in virtual worlds. Its flagship product is VAIL VR, a VR title available on Meta Quest and Steam.

3 investors

Smart Eye develops AI-based eye tracking and automotive-grade Driver Monitoring and Interior Sensing systems, along with Human Insight AI research instruments used across automotive, aviation, behavioral science and other fields. Its subsidiaries include Affectiva (Emotion AI for media, market research and automotive) and iMotions (a biosensor software platform).

3 investors

Again is an AI-native biomanufacturing platform that uses computational biology and proprietary biological data to design molecules for chemicals, materials, agriculture, and food production, replacing traditional petrochemical manufacturing methods.

3 investors

AIM Biotech develops organ-on-chip and 3D tissue culture platforms (idenTx, organiX, and Avatar) for drug discovery and preclinical research. The company provides tools for academic and pharmaceutical researchers to model human tissue microenvironments and accelerate therapeutic development.

3 investors

AiRANACULUS develops AI-powered software for intelligent radio frequency and networking solutions across applications from space to smart cities. The company specializes in autonomous signal processing, spectrum sharing, and self-driving network optimization for congested and contested environments.

3 investors

Airhart Aeronautics designs and builds advanced personal airplanes with a focus on safety, reliability, and intuitive operation. The company serves individuals and operators seeking easier-to-fly, safer aircraft with modern avionics and human-centered design.

3 investors

AirMiners is a community and accelerator organization that gathers entrepreneurs, scientists, and innovators to develop and commercialize carbon dioxide removal solutions. It supports founders building companies in the carbon removal industry.

3 investors

Akave provides isolated, persistent object storage for AI and machine learning workloads, enabling customers to store datasets, model weights, and training artifacts with tenant-level data isolation and compliance capabilities.

3 investors

Alafair Biosciences develops advanced bioresorbable biomaterials for surgical soft tissue healing and motion preservation. The company serves surgeons and patients undergoing procedures requiring post-surgical recovery, with a focus on preventing tissue tethering and supporting natural mobility.

3 investors

Aldoria develops space surveillance technology for Space Situational Awareness (SSA) and Space Traffic Management (STM), serving governments, space agencies, institutions, and commercial satellite operators. The company uses ITAR-free technologies to provide orbital risk management, asset protection, and traffic coordination, with a focus on European space autonomy.

3 investors

Aledia develops next-generation MicroLED display technology based on 3D nanowires grown on silicon, operating a pilot line and high-volume production facility. It manufactures MicroLED semiconductor solutions from its production site near Grenoble, France.

3 investors

Alef develops a flying car designed to drive on streets and take off vertically to fly over traffic. The vehicle targets personal urban mobility.

3 investors

AlensiaXR develops holographic technology that replaces traditional cadavers in medical and dental education. The company serves medical schools, dental schools, and other health professions institutions seeking immersive, accessible anatomical learning experiences.

3 investors

All G produces high-value proteins using precision fermentation technology for infant formula, dietary supplements, and personal care applications. The company manufactures lactoferrin and human milk proteins at scale while maintaining infant formula-grade purity and quality standards for global markets.

3 investors