Deep Tech Startups

Serna builds a platform to unlock the transcriptome as a drug target for drug discovery. The company integrates technology and biology to change drug discovery processes.

5 investors

Sierra Ventures is an early-stage venture capital firm that invests from Inception through Series A in enterprise and frontier technologies, with particular focus on AI infrastructure, vertical AI applications, physical intelligence, and deep tech innovations.

5 investors

Signaloid develops UxHw technology, a compute platform that propagates uncertainty by evaluating a distribution of inputs in a single program execution to produce distribution-based results. It targets stochastic workloads in quantitative finance, AI/ML, robotics, industrial automation, supply chain, and engineering, claiming large speedups over conventional Monte Carlo methods.

5 investors

Silicon Box develops chiplet architecture and semiconductor technologies for advancing frontier technologies. The company combines expertise in front-end chiplet design, back-end semiconductor manufacturing, and ecosystem development.

5 investors

Silurian develops customized foundation models for simulating the impact of weather on assets and infrastructure. The company serves energy and government sectors.

5 investors

Silveray develops flexible X-ray detectors using patented semiconductor ink technology for non-destructive testing in industrial applications including oil and gas, nuclear energy, aerospace, and shipbuilding. The company's Digital X-ray Film product enables imaging in constrained spaces where conventional rigid detectors cannot be deployed.

5 investors

Sinumy develops hands-free authentication technology, described as a first-of-its-kind in Japan and globally. The company builds this deeptech recognition/authentication technology and pursues partnerships and new business ventures around it.

5 investors

Skycore Semiconductors designs switched-capacitor power converter technology, with the Skycore 300 W evaluation kit demonstrating high-efficiency DC-DC conversion for applications requiring compact design and power density.

5 investors

Snips develops embedded, on-device voice recognition technology; it was acquired by Sonos and continues operating in Paris as the Sonos Voice Experience team. The company focuses on bringing voice recognition to audio and connected devices.

5 investors

Snowcap Compute develops superconducting computing platforms using Josephson Junctions to replace semiconductor transistors, delivering orders-of-magnitude greater energy efficiency for AI and high-performance computing workloads. The technology operates on proven cryogenic infrastructure and uses standard semiconductor manufacturing processes.

5 investors

Sofant develops satellite antenna terminals using proprietary RF MEMS technology for mobile connectivity applications including in-flight, maritime, and military communications. The company operates a fabless semiconductor model and focuses on delivering compact, lightweight, low-power solutions.

5 investors

Cellular Intelligence is a cell therapy company developing engineered cell treatments for diseases, including a Phase 2-ready therapy for Parkinson's disease acquired from Novo Nordisk. The company applies computational biology and synthetic biology approaches to reprogram cellular function.

5 investors

Sophia provides modular, space-native edge computing hardware designed to process satellite data in orbit. Their products enable rapid data processing and delivery from space platforms to ground systems.

5 investors

South 8 develops liquefied gas electrolytes for lithium-ion batteries, replacing conventional liquid electrolytes to improve performance, safety, and reliability in extreme temperature environments. The company serves defense and mobility applications through both direct battery cell sales and an electrolyte injection system for manufacturers.

5 investors

Spacebackend builds software infrastructure for integrating multi-vendor aerospace and defense hardware systems, automating the translation of hardware specifications into flight-ready software to collapse integration timelines. The company serves aerospace, defense, and space companies seeking to accelerate the integration and deployment of complex mission-critical systems.

5 investors

Sphere Semi uses an AI engine to design, validate, and fabricate analog chips, starting with RF components and mixed-signal blocks. It delivers custom chips and reusable IP such as LNAs, PAs, filters, SerDes, and ADCs/DACs built to customer specifications.

5 investors

SpinDrive designs, supplies and supports active magnetic bearing (AMB) systems and controller platforms for industrial OEMs whose high-speed machinery depends on bearing performance and lifecycle cost. It offers complete AMB systems, controllers (Magma X100 and X800), and services including feasibility studies, system design, retrofits, condition monitoring and lifecycle support.

5 investors

Standard Cyborg builds cloud and edge tools that let developers and non-developers create, deploy, and improve computer vision applications. It focuses on making computer vision technology accessible for building perception applications.

5 investors

Starlab is developing a commercial space station intended to support microgravity research, commercial innovation, and international collaboration in low-Earth orbit. The company designs, builds, and plans to operate the station to strengthen the low-Earth orbit economy.

5 investors

Stell builds cloud-based software for managing requirements, traceability, and compliance on aerospace and defense programs. Founded in 2022, it serves defense and commercial aerospace contractors and is deployed on U.S. Space Force and Air Force programs.

5 investors

Step Pharma develops oral cancer drugs that inhibit the enzyme cytidine triphosphate synthase 1 (CTPS1), with its lead therapeutic dencatistat in clinical development for lymphoma, solid tumors, and essential thrombocythaemia.

5 investors

Stratum AI uses deep learning to help mining companies predict ore grades and identify optimal drilling locations, replacing traditional statistical interpolation between expensive drillholes. Its technology works for gold as well as base metals such as copper.

5 investors

SWIR Vision Systems designs shortwave infrared (SWIR) cameras and sensors based on colloidal quantum dot (CQD) thin-film photodiodes fabricated on silicon readout wafers. Its Acuros CQD imaging products serve applications such as silicon inspection, laser beam profiling, machine vision, surveillance, and autonomous vehicle imaging.

5 investors

Synthace provides a software platform for experimental design and lab automation, enabling researchers to run Design of Experiments (DOE) workflows across multiple automated laboratory instruments and devices.

5 investors