Deep Tech Startups

HarborSite develops a targeted gene insertion platform that engineers site-specific recombinase enzymes to integrate therapeutic genes into safe genomic sites. It aims to create one-time, durable treatments for genetic and age-associated diseases.

3 investors

Harmonic Discovery applies medicinal chemistry, cheminformatics, data science and machine learning expertise to advance drug discovery. The company is supported by investors at the intersection of technology, biology and medicine.

3 investors

HCVC is a venture capital firm that invests in founders building scientific and technological progress through hardware, robotics, artificial intelligence, and advanced manufacturing innovations.

3 investors

Helix Geospace develops patented helical GNSS antennas (Dielectrix) and anti-jamming CRPx technology for resilient Position, Navigation, and Timing (PNT) applications. Its products serve safety- and mission-critical uses such as aviation, maritime, military, and infrastructure, offering interference-resistant satellite and terrestrial data communications.

3 investors

Hephae Energy Technology develops drilling design and measurement equipment aimed at harnessing the earth's heat for geothermal power, drawing on the founders' background in the energy and oil & gas industries. It focuses on resource-efficient, lower-emission technology for the clean energy sector.

3 investors

Hephaestus Technologies builds AI physics models and machine learning tools for plasma systems research and development, including a plasma solver (PLASMA-gen) that predicts plasma conditions from experimental data and AI-driven materials discovery for superconductors. The company works with research partners including Imperial College London.

3 investors

Hera Health Solutions is a biotechnology company that develops a proprietary nanotechnology platform to reformulate existing pharmaceutical compounds into more effective and longer-acting therapies. The platform enables rapid optimization of drugs with improved release profiles, reduced toxicity, and scalable manufacturing.

3 investors

Hexium develops Atomic Vapor Laser Isotope Separation (AVLIS) technology that uses lasers and electric fields to enrich isotopes, starting with lithium. Its enriched isotopes are aimed at nuclear energy, nuclear medicine, and industrial applications.

3 investors

Hiverge builds an AI discovery engine that uses multiple parallel agents to automatically write and optimise algorithms for critical optimisation problems, from speeding up AI model training to solving combinatorial optimisation tasks. The company was founded by researchers from Google DeepMind and the University of Cambridge.

3 investors

Holonym builds "Human Keys," a system for privacy and security in zero trust environments that gives each individual a key they alone control to access digital personhood, privacy, and security rights. The product uses programmable privacy built on decentralized protocols.

3 investors

Horizon Quantum builds software infrastructure for quantum computing, including Triple Alpha, an integrated development environment with proprietary programming languages and a compiler that lets developers write portable quantum programs at multiple levels of abstraction. It also provides cloud-based deployment and execution infrastructure so users can run quantum applications on existing hardware, aimed at software developers building quantum applications.

3 investors

Hyku Biosciences develops small molecule therapeutics with novel mechanisms of action designed to covalently bind non-cysteine amino acids and inactivate disease-driving proteins. The company operates in drug discovery, using its proprietary Hyku platform to address challenges such as selectivity, druggability, and resistance in disease targets.

3 investors

HyPrSpace develops a scalable hybrid rocket engine based on patented hybrid propulsion technology, aiming to provide Europe with a cost-effective and sovereign launch capability. The company operates in the space launch and propulsion industry and is based in France/EU.

3 investors

Iceberg Quantum designs fault-tolerant quantum computing architectures based on LDPC codes that reduce the hardware overhead for quantum error correction. The company focuses on quantum architecture to make useful quantum computing achievable sooner.

3 investors

Ideon Technologies uses cosmic-ray muon tomography to create subsurface density maps for mining companies, enabling mineral deposit identification and characterization while reducing environmental impact and operational risk.

3 investors

Igloo Vision designs and builds shared immersive spaces—such as cylinders, cubes, CAVEs, and custom rooms—powered by its Igloo Core Engine operating system, which displays 360°, 3D, XR, and everyday enterprise content. It serves organizations across industries for visualization, simulation, engagement, and collaboration.

3 investors

imec.xpand is a venture capital fund investing in technology companies, with a team focused on deep technological expertise and a hands-on approach.

3 investors

Immersal develops a Visual Positioning System (VPS) and city-scale mapping toolkit that provides accurate device localization and spatial mapping for indoor, outdoor, and underground environments. Its technology is used for augmented reality, wayfinding, asset and people tracking, smart city solutions, and last-mile delivery across industries such as retail, sports venues, and oil & gas.

3 investors

Immunophotonics is a clinical-stage biotech company developing novel treatments for solid-tumor cancers and infectious diseases by combining tumor ablation with systemic cancer immunotherapy. The company's intellectual property platform includes IP-001, designed to transform routine ablation procedures into systemically active cancer immunotherapy.

3 investors

Immuto Scientific uses a patented, AI-enabled structural proteomics and mass spectrometry platform to characterize disease-specific surface protein conformations and identify novel targetable epitopes. The company applies this approach to discover targets for cancer therapeutics.

3 investors

Impetus Ag develops early- to late-stage agricultural technologies, with a focus on Bt discovery and development and insecticidal proteins for insect and pest control in crops. It operates in the agricultural biotech sector, building plant trait and biological R&D solutions.

3 investors

Impossible Metals builds underwater robotic vehicles to collect critical metals from the seabed for clean energy applications, with a focus on sustainable and environmentally responsible extraction practices.

3 investors

INBRAIN Neuroelectronics develops graphene-based brain-computer therapeutics that combine neural signal decoding with AI to enable precision, adaptive treatments for neurological disorders. Founded in 2020, it works in the neurotech and medical device field, spanning neuroscience, semiconductors, AI, and clinical development.

3 investors

Inception Labs develops diffusion-based large language models (dLLMs) designed for production applications. Their Mercury model family offers faster inference speeds than traditional autoregressive LLMs while maintaining quality, targeting developers and enterprises building AI systems.

3 investors