Deep Tech Startups

Somewear builds a software-defined edge networking system that routes mission data across narrowband, mesh, and satellite links to keep teams and unmanned platforms connected in contested or degraded conditions. Its hardware and software products, including an ATAK plugin, serve defense, special forces, and emergency response teams needing resilient tactical communications and command and control.

4 investors

Spartan, a radar technology brand of Pro-Vision, develops software-defined radar sensing and collision avoidance systems for commercial vehicle OEMs, Tier 1 suppliers, and fleet operators. Its systems target complex commercial environments such as mining, construction, material handling, and logistics.

4 investors

Specter Aerospace develops hypersonic and air-breathing propulsion vehicles, including scramjets aimed at reaching Mach 5 and beyond, targeting both defense applications for the U.S. Department of Defense and long-range commercial flight. Its work also extends to fuel-saving technologies for applications such as natural gas power plants.

4 investors

SpiNNcloud Systems builds neuromorphic, brain-inspired computing hardware based on its SpiNNaker2 Arm-based AI processors, aimed at running AI workloads at supercomputer scale with higher energy efficiency than GPUs. Its systems target data centers and high-performance computing environments facing energy constraints from GenAI growth.

4 investors

Spore.Bio develops real-time microbial detection technology for industrial quality control, replacing traditional Petri dish culture methods used in factory settings. It combines photonics, AI, and biology to detect, quantify, and identify living microorganisms without reagents or culturing.

4 investors

Standard Nuclear manufactures TRISO nuclear fuel for advanced reactors, establishing a domestic fuel supply chain for the nuclear energy sector in the United States. The company focuses on scaling advanced fuel production to support the deployment of next-generation nuclear power plants.

4 investors

StoreDot develops extreme-fast-charging lithium-ion EV batteries based on silicon and organic-inorganic chemistry combined with nanotechnology and AI, designed to charge in minutes and manufacturable on standard production lines. The company targets electric vehicle makers and the broader mobility market.

4 investors

Stratum.ai develops machine learning solutions for mining operations to address operational challenges and inefficiencies. The company leverages deep expertise in AI systems implementation across agriculture, telecom, pharmaceutical, and retail industries to deliver bespoke AI technology for the mining sector.

4 investors

Supercritical develops a high-pressure, efficient electrolyser technology for producing green hydrogen, enabling industrial transition away from fossil fuels. The company serves industries requiring hydrogen for chemical production, refining, and energy applications.

4 investors

SweGaN produces QuanFINE gallium nitride (GaN) epitaxial wafer materials for device foundries, fabless firms, and system manufacturers. Its materials target RF applications such as 5G telecom, defense radar, satellite communication, and aerospace, as well as high-voltage power electronics for EVs and data centers.

4 investors

Syntis Bio develops oral therapies that use the biology of the small intestine to treat conditions ranging from rare genetic disorders to common diseases. The company is advancing a pipeline of drug candidates across multiple therapeutic areas, beginning with obesity.

4 investors

T-Cypher develops drugs against novel disease-specific targets to treat patients with cancer and autoimmune diseases, focusing on immune-system-engaging medicines. Its approach combines proprietary wet-lab and computational platforms to study cellular communication and identify new therapeutic targets.

4 investors

Tacta Systems is a robotics company building "Dextrous Intelligence," a control system that lets robots perform delicate, variable, human-like tasks with flexibility and autonomy. It develops the underlying technology enabling robots to manipulate objects with greater dexterity.

4 investors

Tahoe Bio AI applies machine learning and computational biology to drug discovery and development. The company leverages AI and advanced cellular modeling for pre-clinical research in the biotech industry.

4 investors

Ten63 develops drug-discovery technology that combines generative chemistry with quantum-accurate molecular simulation, including BEYOND (a large quantum chemistry model) and Sentinel (a virtual CSO for target selection), to design therapeutics against previously undruggable targets. It runs an internal pipeline of first-in-class and best-in-class programs across oncology and other serious diseases.

4 investors

ThayerMahan develops autonomous maritime surveillance and ocean intelligence systems for undersea and offshore monitoring, serving national security and commercial offshore operations. The company focuses on integrated maritime awareness solutions for defense and commercial customers.

4 investors

Thermulon develops and scales the production of high-performance, fire-safe aerogel insulation materials aimed at reducing the carbon footprint of buildings. The company operates from a laboratory in West London and serves the construction sector with its novel aerogel process.

4 investors

ThinkOrbital develops scalable, pressurizable space infrastructure platforms for cislunar space applications including satellite servicing, in-space manufacturing, storage, and refueling. The company serves the commercial space economy by delivering cost-effective, modular structures that assemble autonomously in orbit.

4 investors

Third Dimension builds spatial reconstruction and generation technology that creates high-fidelity digital worlds for autonomous systems to train on and operate reliably in the real world. The company addresses the simulation-to-reality gap that currently constrains autonomous robotics development.

4 investors

TAE Technologies develops hydrogen-boron (aneutronic) fusion power using a beam-driven Field-Reversed Configuration reactor design, aiming to deliver utility-scale fusion electricity to the grid in the early 2030s. Through its subsidiaries, the company also works on grid energy storage solutions and cancer treatment technologies.

4 investors

Twig.bio uses AI and machine learning to generate and score novel microbe designs — covering pathway and enzyme selection, gene edits, and expression levels — through its "dry lab" platform bio:drive, then transfers lab-ready designs to an automated system for growth. The company applies computational tools to accelerate microbial strain design and engineering for biotech applications.

4 investors

Ubicept develops single-photon imaging and perception technology, turning research in the field into practical products for computer vision and camera design teams. Its imaging solutions target industries including mobility, manufacturing, surveillance, and robotics.

4 investors

Ultima Genomics develops genomic sequencing technology to scale omics information for advances in biology and human health improvements.

4 investors

Unispectral designs and manufactures semiconductor MEMS-based hyperspectral chips and spectral camera modules that miniaturize traditional hyperspectral imaging systems into lightweight, low-power devices. Its products, including NIR spectral cameras with USB3 connectivity, target industries such as consumer electronics, smart home appliances, food detection, agricultural monitoring, security, and autonomous driving.

4 investors