Deep Tech Startups

Ambagon develops small molecule stabilizers of 14-3-3 protein complexes to modulate disease-related protein interactions, targeting therapeutic areas including cancer, metabolic disorders, neurodegenerative and infectious diseases.

5 investors

AMPLY Discovery is a UK-based biotech company that uses AI and computational biology to identify therapeutic targets in non-coding regions of the genome and develop first-in-class drugs through an integrated discovery platform combining machine learning with wet-lab validation. The company is developing therapeutics for oncology and drug-resistant infectious diseases, particularly antimicrobial-peptide and long non-coding RNA oligonucleotide programmes.

5 investors

Andon Labs develops safety systems and protocols for autonomous AI-driven organizations, focusing on AI alignment and control mechanisms for agents that operate without human oversight.

5 investors

Animab develops proprietary antibodies that mimic natural intestinal protection mechanisms to safeguard piglets' health during post-weaning, a critical period in livestock production. The company's biologically-derived solutions target specific intestinal pathogens without disrupting the healthy microbiome.

5 investors

ANRA Technologies provides end-to-end drone operations and traffic management software for uncrewed system operators and airspace managers, including UAS Traffic Management (UTM) and Urban Air Mobility (UAM) capabilities. Its products include ANRA Mission Manager for enterprise drone operations and ANRA Delivery for drone delivery, deployed with government aviation authorities worldwide.

5 investors

Avvio Medical develops Microbubble SonoLithotripsy, a minimally invasive outpatient procedure that uses low-intensity ultrasound to break down ureteral stones without requiring general anesthesia or stents. The technology is designed for clinical-stage development and aims to reduce treatment wait times and expand access to stone care in various clinical settings.

5 investors

Applied Brain Research develops on-device AI technology optimized for resource-constrained edge devices, enabling responsive and energy-efficient AI capabilities. The company serves enterprises and product developers seeking to deploy AI applications on hardware with limited computational resources.

5 investors

Arkeus builds AI-powered sensing systems that combine advanced sensors with onboard AI to give autonomous platforms real-time situational awareness at the edge. Its technology integrates across drones, aircraft, unmanned surface vessels and ground-based surveillance systems for defense, security and civil applications.

5 investors

Arm is a semiconductor company that designs and licenses processor IP and compute platforms used from edge devices to AI data centers, spanning markets such as data centers, automotive, and general computing. It is a publicly traded company majority-owned by SoftBank Group.

5 investors

Arsenale builds an end-to-end biomanufacturing platform that combines micro-scale bioreactors, AI software, and large-scale fermentation infrastructure for precision fermentation at industrial scale. The system spans organism design in the lab to industrial production, targeting bio-based production of food, materials, and goods.

5 investors

AstroX is a Japanese space transportation company developing hybrid rocket and propulsion technology to build domestic space launch infrastructure. It is headquartered in Minamisoma, Fukushima, with facilities including an R&D center and factory.

5 investors

Asylon provides an automated perimeter security platform combining aerial drones, ground robots, and AI-powered monitoring to protect corporate campuses, logistics facilities, and critical infrastructure. The company serves organizations looking to reduce security costs and staffing demands through integrated robotic systems managed by a 24/7 security operations center.

5 investors

Asynchronics develops NeXosim, a simulation framework for space systems that enables high-fidelity modeling and validation of spacecraft and satellite hardware. The company serves space agencies, manufacturers, and satellite operators with tools for digital twin and functional simulation.

5 investors

Atelerix develops patented alginate hydrogel technology that stabilises cells, tissues, blood products, viruses and vectors at room temperature, removing the need for cryopreservation and cold-chain shipping. Spun out of Newcastle University, it serves researchers, biotech firms and diagnostics teams needing to store and transport biological samples.

5 investors

Atrandi makes Flux, a device that isolates thousands to hundreds of thousands of individual cells simultaneously into semi-permeable capsules for downstream genomic and microbial analysis. The system is designed for life science research and can operate in field settings or laboratory environments.

5 investors

Autobahn Therapeutics develops orally administered small molecule prodrugs using a brain-targeting chemistry platform to create regenerative medicines for central nervous system (CNS) disorders. The company targets both rare and prevalent brain diseases, using biomarker-driven development strategies to demonstrate on-target activity early in clinical trials.

5 investors

Ava Labs is a company building blockchain infrastructure and tools for creating and using finance applications. Its team spans computer science, economics, finance, and law, with a focus on decentralized finance technology.

5 investors

Avathon develops an AI-powered technology platform for industrial operations that extends the lifespan of critical infrastructure and enables autonomous industrial processes. The company serves industrial operations teams managing complex infrastructure systems.

5 investors

Avidity Biosciences develops Antibody Oligonucleotide Conjugates (AOCs) that combine monoclonal antibody specificity with oligonucleotide precision for targeted delivery of RNA therapeutics to treat rare genetic muscle diseases. The company has three clinical-stage programs targeting myotonic dystrophy type 1, facioscapulohumeral muscular dystrophy, and Duchenne muscular dystrophy.

5 investors

Avisi Technologies develops nanotechnology-enabled implantable devices to lower intraocular pressure in patients with open-angle glaucoma. Its products are investigational ophthalmic medical devices currently in clinical trials.

5 investors

Axine Water Technologies develops electrochemical oxidation technology to destroy PFAS, pharmaceuticals, solvents, and other persistent organic contaminants in industrial wastewater. It offers a treatment-as-a-service model with on-site systems aimed at helping industrial operators meet wastewater compliance regulations.

5 investors

BANIQL uses an atmospheric-pressure leaching process to convert nickel ore into battery-grade mixed hydroxide precipitate (MHP), with nickel sulfate and nickel metal in development, avoiding HPAL autoclaves and using far less energy. It operates a pre-pilot facility in Indonesia and targets battery-material supply chains, with residues repurposed into agricultural fertilizer and magnesium products.

5 investors

Barnwell Bio runs a biosurveillance platform that analyzes environmental samples such as waste streams to detect pathogen trends and provide animal health data. It serves livestock and poultry producers and veterinarians, offering data to guide disease management and evaluate feed additives, vaccines, and biosecurity protocols.

5 investors

Baseimmune develops active immunotherapies using computational design and protein engineering to create custom antigens aimed at chronic diseases. The company operates in the biotech and therapeutics space.

5 investors