Deep Tech Startups

ReturnZero (리턴제로) is a South Korean company developing AI-based speech recognition technology, positioned as an interface to help people interact with machines more naturally.

1 investor

Rubryc discovers antibody-based medicines for obesity and cardiometabolic disease, using an AI-assisted platform to design antibodies for hard-to-drug targets. The company focuses on therapeutic development for patients with limited treatment options.

1 investor

Runa Capital is a global venture capital firm founded by serial entrepreneurs that invests in early-stage software and deep tech startups worldwide, focusing on deeptech, enterprise software, and fintech infrastructure. It writes first checks of $0.5-5M at the pre-seed, seed, and Series A stages, with over $600M in assets under management.

1 investor

RUNWITHIT Synthetics builds "Synthetic Twins," dynamic 6D digital replicas of real places that combine 3D GIS with context, time, and simulated populations on its HoloDeck platform. It uses generative and agentic AI to model outcomes—such as wildfire evacuations, policy impacts, or transit changes—for decision-makers addressing complex urban, economic, and social challenges.

1 investor

Ruya Ventures is a venture capital firm that invests in deep tech founders at the earliest stages, maintaining a highly concentrated portfolio. It supports company building across commercialisation, manufacturing, supply chains, team formation, and global market expansion, working across Europe, the US, and Asia.

1 investor

Rx Bandz develops auto-injector devices and injectable formulations for treatment conditions including anaphylaxis, diabetes, opioid overdose, and other medical emergencies for patients, first responders, and military personnel.

1 investor

RyboDyn develops breakthrough immunotherapies by identifying and targeting previously hidden disease markers through its proprietary RyboCypher™ technology platform. The company serves patients in need of next-generation treatments for diseases associated with cryptic biological targets.

1 investor

Rypplzz builds a 3D positioning infrastructure, described as a spatial intelligence layer, that runs across telecom networks to turn physical space into a programmable layer for coordination and automation. It works with telecom operators, carriers, and government agencies.

1 investor

S-Graphene is a materials company that develops graphene application technology, including mass-production methods for forming nano-holes in graphene and growing graphene on metal. It supplies customized nano-materials for next-generation products in industries such as secondary batteries (as anode and separator materials), semiconductors, filters, and bio applications.

1 investor

S2 Corporation provides research and development services and has secured over $25 million in Small Business Innovation Research (SBIR) funding from the U.S. Small Business Administration since 2002.

1 investor

S2C (思尔芯) develops EDA tools for semiconductor chip design and verification, including architecture design/modeling software, hardware emulation and prototyping systems, formal verification, and debug and cloud-based compute management platforms. Its products serve IC design companies working on SoCs for automotive electronics, CPU, AI, 5G, and cloud computing applications.

1 investor

Saab is a global defense and aerospace company that develops and sells solutions to governments and defense organizations across over 100 countries.

1 investor

Sabi is a California-based startup building a wearable beanie with custom neuroimaging sensors and ASICs that reads brain signals to convert thoughts and attempted speech into text. It combines a large neural decoding dataset with a Brain Foundation Model to map brain activity to thoughts and drive AI agents.

1 investor

Sabrewing Aircraft Company designs and builds aircraft, with development based at Hayward Executive Airport in California.

1 investor

SafeBVM develops flow-limiting devices and monitoring systems for manual bag-valve-mask ventilation used in emergency and critical care settings. The company's products help healthcare providers deliver consistent, patient-safe ventilation in cardiac arrest, overdose, and brain injury scenarios.

1 investor

SafeSense Technologies is an engineering consulting firm that develops and produces sensor technology using flexible hybrid electronics, offering technical services from concept to production. It works with client organizations either independently or collaboratively.

1 investor

Safi Biotherapeutics manufactures adult stem-cell derived human red blood cells (mRBCs) as a cell therapy blood transfusion product, aiming to produce them at industrial scale for civilian and military transfusion needs. Its work targets both chronic transfusion indications, such as sickle cell disease, and acute settings including hospitals and battlefields.

1 investor

SageRAN Technology develops mobile communications hardware and software, including full-stack 4G/5G/5G-A protocol stacks, base stations, core networks, satellite communication equipment, and edge AI communication products. It serves telecom operators, enterprises, vertical industries, special communications users, and satellite internet projects across domestic and international markets.

1 investor

SAILWINT produces hydrogen and electricity from autonomous sailing wind turbine ships that operate in offshore waters. The company targets energy producers and maritime industries seeking clean power generation at scale.

1 investor

Salacia Technologies is a science and engineering company developing technologies for desalination and treatment of seawater and industrial wastewater across a range of salinity levels. It focuses on reducing the environmental impact and cost of brine treatment for industries including desalination, oil and gas, mining, and lithium extraction.

1 investor

Salem Robotics develops autonomy software for robotic radiological surveys and inspections in nuclear and hazardous environments. The platform automates route planning, radiation measurement collection, and compliance reporting on existing robot hardware to reduce worker exposure and improve data consistency.

1 investor

A company providing security and compilation expertise, with team experience ranging from advanced compiler development to nation-state security work and early blockchain contributions.

1 investor

Salinity Solutions develops water treatment technology and has raised funding through grants, crowdfunding, and venture capital. The company is currently running an investment round via Crowdcube ahead of a planned institutional funding round.

1 investor

Sallea manufactures salt cores and molds used in casting and composite manufacturing workflows. The cores dissolve in water without additional chemicals, enabling complex shapes and environmentally responsible post-processing.

1 investor