Deep Tech Startups

River is developing a speech brain-computer interface (BCI) that operates without touching the brain, aimed at restoring and augmenting human communication. The company collaborates with academic and clinical research partners in neuroscience and neural engineering.

1 investor

RiverD designs and manufactures non-invasive skin analysis devices based on Raman spectroscopy technology for scientific research, clinical applications, and industrial use. The company's instruments provide precise insights into skin composition and topical product penetration.

1 investor

RNA Connect develops uMRT, a reverse transcriptase enzyme for end-to-end cDNA synthesis that copies full RNA transcripts, including large viral genomes, in a single pass. The technology is aimed at gene expression, regulation, and discovery research applications in the life sciences.

1 investor

Roadrunner Venture Studios is a venture studio that builds and invests in deep tech startups across energy, advanced manufacturing, quantum, and advanced materials. It partners with universities, national labs, and the private sector to develop ideas, and works alongside America's Frontier Fund with a focus on American technological competitiveness.

1 investor

Robert Allan Ltd. is a marine design firm that develops vessel designs for diverse global markets. The company has operated since 1930 and specializes in naval architecture and marine engineering services.

1 investor

roboa develops robotic technology for deploying fiber optic cables in existing ducts and conduits where traditional methods fail. The solution targets telecommunications operators and fiber network rollout teams seeking to reduce deployment costs and timelines.

1 investor

Robocurve develops open-source tools and benchmarks for evaluating the real-world capabilities of AI systems and robots. The company serves robotics labs and the broader public by providing independent, rigorous evaluation frameworks to assess progress in physical AI and general-purpose robotics.

1 investor

Robodinamika develops complex engineering and technical solutions, with licensing in project design and construction. The company serves clients requiring specialized industrial engineering services in Russia.

1 investor

The Robotics Factory supports the development of robotics startups in Southwestern Pennsylvania by providing workforce development, resources, and funding through Create, Accelerate, and Scale programs that connect emerging companies to regional manufacturing capabilities.

1 investor

Robotto develops autonomous systems for use in wildlife conservation, emergency response, infrastructure, and defense sectors. The company emphasizes early collaboration with end-users and rapid testing cycles to accelerate deployment of its technology.

1 investor

Robros develops full-stack humanoid robots designed to work alongside humans in industrial environments, building both the hardware and AI intelligence required for autonomous collaboration. The company creates a Physical AI platform based on biped locomotion and real-time control technology that enables robots to operate naturally in real-world settings.

1 investor

ROBUST AO GmbH develops laser cutting technology using dynamic beam oscillations to improve speed and quality in cutting operations. The company serves industrial applications requiring precision laser processing.

1 investor

Rockstart is an investment and accelerator platform that supports early-stage companies.

1 investor

Collins Aerospace designs and delivers aerospace solutions and systems across commercial, regional, business, and military aviation markets.

1 investor

Rocscience develops modelling, analysis, and design software for engineering disciplines including geotechnical, mining, structural, hydrogeology, and energy applications. The company serves engineers and geoscientists who need rigorous tools for collaborative decision-making in infrastructure and safety-critical design projects.

1 investor

Rocsole develops hybrid process flow management systems and software with sensor technology for safety-critical and pollution-challenged industries. The company focuses on cleantech solutions that improve operational safety, cleanliness, and efficiency across sectors including oil & gas and medtech.

1 investor

Roctool develops heat and cooling technology for rapid molding processes used in composite, plastic injection, and metal manufacturing. The company serves industries including automotive, aerospace, electronics, and consumer goods.

1 investor

Rodatherm develops waterless geothermal energy systems for rapid electricity generation using proven drilling technology, targeting sedimentary basins in the US and beyond. The company applies oil and gas operational expertise to make geothermal projects faster, simpler, and economically scalable for grid decarbonization.

1 investor

RodRadar manufactures excavator bucket units embedded with ground-penetrating radar technology to detect buried utilities in real-time during excavation. The system alerts operators to the presence of gas, power, communications, water, and other underground infrastructure to prevent accidental strikes.

1 investor

Roka Furadada is a Barcelona-based deep biotech company that develops patented solar active ingredients for the cosmetics industry, including a photo-adaptive UVA absorber and upcycled lignin-based multifunctional actives for skin, sun, and hair care. It co-creates products with formulators, R&D leads, and marketing teams at cosmetics brands, guiding them from molecular design to market launch across global markets.

1 investor

Rosebud Biosciences develops therapies for rare genetic diseases in children by creating organoid models that replicate patient genetic mutations and using drug screening to identify potential cures. The company uses human-derived organoids combined with robotics and machine learning to accelerate drug discovery across cardiac, hepatic, neural, and kidney disease targets.

1 investor

Roshan Water develops water-testing technology, drawing on scientific research and commercialization expertise to move lab innovations into practical field-deployable systems. The company serves users who need water quality assessment capabilities.

1 investor

Rovial develops high-power systems for satellites, aiming to provide greater in-orbit power capacity at lower cost than current 25-30KW satellites. It targets GEO/MEO applications such as in-orbit data processing, secure data centers, in-orbit manufacturing, high-power radars, detection payloads, lasers, and lunar missions.

1 investor

ROWIAK worked on laser-based solutions for eye care in the field of ophthalmology. The site now indicates the company has closed and redirects visitors to a personal site of Holger Lubatschowski.

1 investor