Deep Tech Startups

MIT Alumni Angels Northern California is an investment network of MIT graduates that provides capital and mentorship to early-stage startups in the Silicon Valley region.

1 investor

SANSHO Co., Ltd. is a Japanese drug-development company creating pharmaceuticals based on cyclic phosphatidic acid (cPA), including 2-carba-cyclic phosphatidic acid candidates in clinical trials for knee osteoarthritis and pulmonary fibrosis. The company conducts research and development to bring these medicines to clinical use.

1 investor

Santero is a Belgium-based biotech company developing antibacterial drugs, including an RSH inhibitor programme targeting Pseudomonas aeruginosa and multidrug-resistant pathogens. It runs drug discovery and preclinical development spanning computational chemistry, medicinal chemistry, and screening toward clinical development.

1 investor

Sapala Organics is a contract research and manufacturing organization (CRO/CDMO) specializing in nucleic acid chemistry, oligonucleotide synthesis, and medicinal chemistry for the pharmaceutical industry. Now a subsidiary of Cohance Lifesciences, the company provides drug discovery and development services focused on genetic therapies and complex small molecule synthesis.

1 investor

Saphlux develops monolithic full-color micro-LED display technology and quantum dot COB display panels for AR smart glasses, sports intelligence glasses, and large-format business and home theater screens. The company provides micro-LED solutions, including semi-polar and photoluminescent quantum dot technologies, for display manufacturers and device makers.

1 investor

SAPIEN develops Micro-LED display driver solutions, including LEDoS (LED-on-Silicon) backplane technology for compact, low-power micro-display engines and MPD (Micro Pixel Driver IC) for backlight and display applications. Its products target AR smart glasses, head-mounted displays, military displays, TVs, and signage, and the company offers custom design from development through mass production.

1 investor

Sapient Perception is a physical AI company building a perception layer that combines ultra-high-resolution sensing with intelligent edge processing, using its IGNITE framework to turn sensor data into real-time actionable intelligence. It targets autonomous platforms and mission-critical decision-making, with roots in ultra-high-resolution UAV cameras for geospatial, industrial, and defense applications.

1 investor

SapientX builds AI-powered 3D digital characters and assistants for commercial deployment in automotive, retail, healthcare, hospitality, and other locations. The company develops virtual workers that can interact with customers and staff in physical environments.

1 investor

Sarama is an AI research lab studying non-human and interspecies communication, with a first consumer product in the form of a dog collar. The company applies its work decoding animals such as whales and dolphins to help pet owners understand their dogs.

1 investor

Sarvam provides a sovereign AI platform with frontier-class models and infrastructure for building conversational agents and applications in Indian languages. The platform serves enterprises and developers across India with deployment flexibility across cloud, private, on-premises, and air-gapped environments.

1 investor

Sateliot develops a low-earth orbit satellite constellation delivering 5G IoT connectivity via non-terrestrial networks (NTN) to unconnected regions and IoT devices globally. The company operates standardized 3GPP-compliant satellite infrastructure for delay-tolerant applications across Europe and beyond.

1 investor

Sauvie is developing a protein discovery platform in the biological intelligence space. The company's website is a pre-launch placeholder with limited details.

1 investor

SavantX develops quantum computing and AI-powered solutions for real-world optimization problems, serving government, defense, and commercial enterprises. The company applies quantum-hybrid technologies and advanced data analytics to address complex computational challenges.

1 investor

Savion develops an LNG-powered small aircraft called the SavionJet to provide on-demand private air travel at lower cost and with reduced emissions. The company targets everyday travelers seeking flexible, frequent travel with a more sustainable alternative to commercial aviation.

1 investor

SCA Automotive Engineering provides consulting and engineering support services to automotive manufacturers navigating industry transformation, including CASE technology adoption, resource optimization, and digital development processes.

1 investor

Scale Biosciences develops patented single-cell analysis technology that enables researchers to conduct massively parallelized sequencing at reduced cost. The company serves biomedical research labs seeking to study complex cell biology at scale.

1 investor

SCALE Lasers develops miniaturized mid-infrared quantum cascade surface-emitting lasers based on a VCSEL-style architecture, aimed at making high-end spectroscopy available in compact components. Its technology targets applications that move lab-grade diagnostics into everyday devices.

1 investor

ScandiBio Therapeutics is a biotechnology company developing therapeutics based on research from leading Swedish and UK academic institutions. The company was founded by researchers from KTH Royal Institute of Technology, Karolinska Institutet, Sahlgrenska Academy, and King's College London.

1 investor

Scandy builds 3D scanning and analysis technology, including one of the first 3D scanning apps made for the iPhone X, and consults on 3D-related problems. The company develops tools for scanning, analyzing, and measuring in 3D.

1 investor

Scantinel develops integrated FMCW LiDAR technology on a chip at 1550nm for autonomous vehicles and industrial applications. The company's solution is designed for mass production and automotive, mobility, trucking, and industrial safety use cases.

1 investor

SCATR provides "Zero Trust Transit," a security overlay that protects data in motion by segmenting, camouflaging, and distributing traffic across multiple paths to defeat traffic analysis, metadata fingerprinting, and quantum "harvest now, decrypt later" attacks. It targets defense, intelligence, and critical infrastructure operators as well as commercial sectors like finance, healthcare, and crypto, adding a transit-layer to existing encryption and Zero Trust stacks.

1 investor

Scatter is the developer of Depthkit, software for volumetric filmmaking and 3D video capture. The company is an Emmy award-winning team that pioneered volumetric filmmaking tools for creators.

1 investor

Schrödinger develops a physics-based computational platform for discovering and optimizing molecules, used to accelerate drug discovery and materials design. The company also operates a therapeutics group that pursues drug development on validated targets and offers educational resources for the field.

1 investor

sciartsoft is a technical research and writing site covering topology optimization, generative design, and multi-objective optimization for engineers, researchers, and design teams. It publishes articles, method comparisons, and case-study analyses focused on connecting computational design methods with practical engineering decisions in fields such as aerospace, automotive, and mechanical systems.

1 investor