Deep Tech Startups

Organ Recovery Systems develops organ preservation products and services, including machine perfusion technology for donor kidneys, for transplant programs and transplant professionals. The company supports over 400 transplant programs across 49 countries and also provides clinical and technical support services.

1 investor

Organo-ID develops iPSC-derived organoid systems, including 3D hepatocyte models, to test drugs in better-modeled biological systems for predictive diagnostics and personalized therapies. The company serves drug development and treatment applications in oncology and rare disease, operating from Turkey with a global focus.

1 investor

ORIA is a Paris-based company, spun off from ENS Paris in 2022, that uses a proprietary mechanical microfluidic platform to extract intact, high-purity functional organelles at industrial scale. Its organelle products serve pharmaceutical companies, biotech firms, and academic institutions for drug discovery, disease modeling, and therapeutic research.

1 investor

Orienspace develops specialized wireless data link communication systems for airborne platforms operating in complex environments. The company manufactures compact, low-latency transceivers that enable long-range command, telemetry, video, and image transmission for high-speed aircraft and unmanned aerial systems.

1 investor

Origami Therapeutics is a preclinical-stage biopharmaceutical company developing protein degrader therapeutics to treat neurodegenerative diseases, starting with Huntington's disease. The company uses a proprietary platform that harnesses the body's natural protein disposal system to degrade disease-causing proteins.

1 investor

The company develops industrial additive manufacturing technology, offering 3D printers, materials, and software for applications from functional prototyping and tooling to small-batch and production parts. It serves manufacturers across industries such as automotive with technologies including FDM, PolyJet, P3, SAF, and SLA.

1 investor

Origin Robotics develops autonomous systems for European and NATO defense markets, combining cost-efficient hardware with advanced software to address modern battlefield challenges.

1 investor

Pareon Biosystems has developed a multiplex biomarker quantification method that produces absolute measurements with built-in correction for non-specific binding. The approach uses low concentrations of common reagents and standard lab equipment such as PCR, targeting personalized/precision medicine applications in research and clinical settings, including resource-limited environments.

1 investor

Oritain provides supply chain traceability and verification services using forensic analytical techniques to authenticate products and combat fraud, serving organizations across industries seeking to verify supply chain integrity and sustainability claims.

1 investor

ORKID develops electric unmanned aerial vehicle platforms designed for diverse commercial applications across industries. The company focuses on making advanced drone technology accessible through flexible, reliable hardware-software integration.

1 investor

Orogen Therapeutics uses AI and machine learning to accelerate drug discovery, focusing on small molecule candidates for immuno-inflammatory diseases. The company combines computational chemistry, DNA-encoded library technology, and medicinal expertise to develop novel therapeutic medicines.

1 investor

Orpheus Ocean develops remotely operated and autonomous vehicles that enable exploration and data collection in deep ocean environments, including the hadal zone below 6,000 meters, serving oceanographic research, conservation, and resource management applications.

1 investor

OSCP builds inertial sensors for autonomous systems that operate in environments without reliable satellite signals, such as tunnels, mines, and underwater settings. The company manufactures these sensors in Canada without US-controlled content.

1 investor

Oshima is a metascience company building a new way to represent scientific literature, breaking research papers into claims, experiments, and evidence rather than treating papers as the base unit of knowledge. Its first product, Modular, decomposes papers into linked claims and evidence to help researchers measure and attribute research contributions more accurately.

1 investor

OSMOS X develops ion propulsion and plasma-based systems for reusable, high-efficiency orbital vehicles aimed at satellite transportation, in-orbit servicing, and space debris mitigation. The NewSpace company targets space logistics for satellite operators and space agencies, with long-term ambitions toward lunar and Martian cargo transport.

1 investor

A medical device CRO (Contract Research Organization) and innovation platform that provides incubation, development, and commercialization services for medical devices and healthcare technologies in China and internationally.

1 investor

Ossianix develops TXP1, a brain-selective shuttle based on a deimmunised VNAR antibody scaffold that targets TfR1 to carry therapeutic payloads across the blood-brain barrier. The company focuses on improving delivery of central nervous system therapeutics to the brain.

1 investor

Ostendo develops a Quantum Photonic Imager (QPI) display platform used to build devices such as augmented reality glasses and light field holographic displays. Its technology targets consumer, enterprise, and defense applications.

1 investor

OTB is a venture capital firm that invests in deep-tech startups, backing founders at late Seed and Series A stages and supporting their global expansion.

1 investor

OTIF Ventures is a venture capital firm that identifies and invests in high-quality technology and life science spinouts, particularly from Oxford University, providing ongoing board-level support to portfolio companies.

1 investor

Bond provides personal safety and security services through a mobile app, combining 24/7 trained security agents with artificial intelligence technology to monitor users and intervene in non-emergency situations. The service targets individuals, families, companies, and institutions seeking enhanced security and peace of mind beyond traditional 911 emergency response.

1 investor

Oureon Technologies develops sensing systems — including radar, acoustic sensors, passive RF, and airspace awareness software — for defense, public safety, and critical infrastructure customers. It serves the US military, American cities, and allied nations.

1 investor

Outpost Technologies develops technology solutions for government and commercial customers.

1 investor

Overlord Labs designs its own battery management systems, including custom silicon chips and firmware, built for the power demands of AI devices. The technology measures, models, and controls battery behavior in real time.

1 investor