Deep Tech Startups

Oversight develops a collaborative edge-AI operating system for critical operations, supporting mission planning, training, live execution, and debrief for military and law enforcement units. Its platform uses data fusion, computer vision, and AI-driven insights, and has been used by IDF and police special operations forces.

1 investor

Ovomind builds an end-to-end platform that converts biosignals from a patented smartband into real-time emotional data, delivered via SDKs and a cloud AI engine for companies to create emotion-aware products, services, and interfaces. It serves hardware makers, product designers, and developers across sectors such as mobility, wellness, and entertainment, and offers hardware and software licensing of its patented biosensing architecture.

1 investor

OVER builds a decentralized spatial intelligence platform that trains Large Geospatial Models on 3D mapping data to support robotics, machine perception, and spatial AI, and offers AI-powered tools for creating and publishing AR/XR experiences tied to real-world locations. It serves both enterprises and Web3 participants through a DePIN model where users can own spatial domains and share revenue from B2B XR publishing.

1 investor

OVER builds geospatial AI models and spatial intelligence tools trained on 3D mapping data, serving robotics, autonomous systems, and XR developers. The company offers large geospatial models, precision navigation systems, and AI-powered tools for creating augmented reality experiences.

1 investor

OXECO is an Oxford University spin-out that develops ultra-thin functional coatings using its ONTO™ surface-modification chemistry based on reactive carbenes applied via wet coating techniques. It serves manufacturers in purification, bioprocessing, and high-value manufacturing to enhance material surface performance.

1 investor

Oxford Investment Opportunity Network (OION) is a business angel network that connects investors with early-stage, high-growth UK companies eligible for EIS or SEIS tax relief. The network facilitates pre-screened investment opportunities across sectors including deep tech, AI, life sciences, and clean tech, with typical deal sizes between £100,000 and £2,000,000.

1 investor

Oxford nanoSystems (OnS) develops coating technologies that improve electrolysers and heat exchangers, allowing them to be smaller, lighter, more efficient and lower cost. The company focuses on coatings for alkaline water electrolysers to produce hydrogen more efficiently for clean energy applications.

1 investor

Oxford Semantic Technologies develops RDFox, an in-memory knowledge graph and semantic reasoning engine that uses logic-based inference to deduce new facts and deliver explainable, auditable results for AI applications. It targets enterprises needing high-performance, scalable knowledge graphs, with a footprint compact enough to be embedded on edge and mobile devices.

1 investor

P3 Therapeutics is developing a new class of anti-inflammatory small chemical molecules and works with partners on a humanized gut-entheseal organ-on-chip platform to study their mechanism of action, pharmacokinetics, pharmacodynamics, and biomarkers. The work is part of an application to the EUROSTARS 3 program under the TRIGG3R project.

1 investor

Heidi Health is an AI-powered clinical documentation platform that captures patient encounters through real-time transcription and automatically generates structured clinical notes, reducing administrative burden on clinicians. The platform serves healthcare providers globally across 116 countries and supports workflow automation including task coordination, clinical coding, and patient outreach.

1 investor

Pacific Biosciences manufactures consumables and reagent kits for long-read DNA and RNA sequencing platforms, serving genomics research and diagnostics labs.

1 investor

Packet Digital develops power systems and power management technologies for autonomous systems operating in air, sea, land, and space, including unmanned aircraft and solar products. It also provides engineering services and embedded software work for these applications.

1 investor

PAGE Technologies provides real-time environmental monitoring using solid-state sensors and AI analytics to deliver continuous visibility into chemical, physical, and biological signals for operational and regulatory compliance.

1 investor

PAL Italy is a robotics company specializing in research, development, and deployment of robotic systems for industrial and healthcare applications in Italy. The company serves Italian industries and healthcare sectors facing labor shortages through automation research, platform distribution, and real-world robot implementation.

1 investor

Palatial converts real objects and environments into physics-accurate, verifiable 3D simulations via an API, generating physics-ready assets at scale to train physical AI and foundation models. Its outputs are formatted for robotics simulators such as NVIDIA Isaac Sim, Newton, and MuJoCo, serving robotics and machine learning teams.

1 investor

Palm Therapeutics develops palmitoylation-targeted drugs using its proprietary PalmReader screening platform to identify novel therapeutic molecules. The company focuses on modulating protein palmitoylation, a post-translational modification involved in multiple disease pathways.

1 investor

Pangolin Therapeutics develops Pangomers, synthetic molecules designed to target and interfere with intrinsically disordered proteins involved in Type 2 Diabetes, neurodegeneration, and cancer. The company uses molecular modeling and drug discovery tools to create therapeutics for previously undruggable protein targets.

1 investor

panluminate develops instruments and processes for whole-brain connectomic mapping at scale, using its pan-ExM imaging technique to capture both neural wiring and molecular state simultaneously at 15nm resolution. It serves neuroscience research institutions with products and services that combine high-resolution microscopy and AI-based segmentation of brain circuitry.

1 investor

Panthura develops non-viral DNA delivery technology for sustained therapeutic effects in specific tissues, with potential for repeated administration. The company is advancing its platform through preclinical and clinical development stages.

1 investor

Pantograph is a research lab developing generally intelligent robots using scalable methods. Its work includes Pan 1, a foundation model trained on Minecraft gameplay videos that can accomplish goals it was not explicitly trained on.

1 investor

Papcup develops a non-invasive cervical screening platform using electrochemical biosensing technology to provide faster, more accessible diagnostics. The company targets women seeking cervical cancer screening and aims to expand its biosensor-based approach across broader healthcare diagnostics.

1 investor

Paradigma builds infrastructure for autonomous research, enabling automated research workflows and operations.

1 investor

Paragon provides instrumentation and control (I&C) life-cycle management for nuclear power plants, including third-party component repair, reverse engineering, and digital system replacements. It serves nuclear facility operators seeking alternatives to costly OEM upgrades to extend the life of aging I&C assets.

1 investor

Parallel Flight develops heavy-lift unmanned aerial vehicle (drone) technology for applications such as aerial firefighting and industrial operations. The company builds hardware, systems, and control software for long-endurance heavy-payload drones.

1 investor