Deep Tech Startups

Type One Energy is a fusion energy startup founded by stellarator experts to design and commercialize a next-generation stellarator fusion power plant. The company develops fusion power plant technology and is working toward the first commercial fusion energy plant.

8 investors

Ubicept develops single-photon imaging and perception technology, turning research in the field into practical products for computer vision and camera design teams. Its imaging solutions target industries including mobility, manufacturing, surveillance, and robotics.

8 investors

Uravu develops water extraction technology using proprietary liquid salts to harvest moisture from air, serving water-stressed regions with scalable on-site and industrial solutions. The company operates India's first commercial atmospheric water generation plant.

8 investors

VEIR manufactures low- and medium-voltage superconducting systems that deliver electricity for high-performance AI data centers. The company serves hyperscalers, chip developers, and data center operators seeking increased power density and reliability.

8 investors

Velaura develops high-performance, energy-efficient computing solutions optimized for AI and advanced computing applications. The company was founded by engineers and executives with experience from major technology firms in semiconductors, networking, and computing infrastructure.

8 investors

Vincere Biosciences develops small-molecule therapeutics targeting mitochondrial quality control and mitophagy, primarily for neurodegenerative diseases including Parkinson's disease. The company translates computational biology and drug discovery into disease-modifying treatments for CNS disorders.

8 investors

Vitrealab develops and manufactures display components for augmented reality glasses using proprietary laser waveguide technology, produced in a dedicated cleanroom with custom fabrication processes.

8 investors

Voyager Technologies builds defense and space systems, including solid-fuel and electric propulsion, energetics (the only U.S. provider of black powder), radiation-hardened space electronics, guidance and navigation systems, lunar and long-duration spaceflight infrastructure, and signals-intelligence/spectrum-dominance software. It serves U.S. and international government agencies, defense primes, academia, and commercial and civil space programs.

8 investors

Whisper Aero develops electric propulsion technology for aircraft, emphasizing quiet, efficient thrust for urban air mobility and logistics. The company targets aircraft manufacturers and operators seeking next-generation propulsion systems for manned and unmanned vehicles.

8 investors

Windborne Systems collects atmospheric data using long-duration balloons and applies AI models to produce weather forecasts for business applications. The company operates in weather intelligence and meteorological data services.

8 investors

Xwing, an autonomous aviation company, is now part of Joby Aviation.

8 investors

Zeta Surgical develops an AI and computer vision-based navigation and robotics platform for image-guided surgery and targeted neuro-therapeutics, enabling high-accuracy image guidance at the point of care. Its products are FDA-cleared and commercially available in the United States.

8 investors

AIRNA develops genetic medicines that use ADAR, a naturally occurring human protein, to precisely edit RNA and treat genetic diseases without permanently modifying DNA. The company targets diseases where the underlying genetic mechanism is well-established and difficult to address with existing therapeutic approaches.

8 investors

STRM.BIO develops technology to deliver gene therapies, aiming to improve how these treatments reach patients. The company operates in the biotech sector, focused on advancing gene therapy for patients worldwide.

7 investors

2AB BioscienceS develops first-in-class small molecule therapeutics targeting the 5-HT2A receptor for ophthalmology and central nervous system disorders. The platform uses structure-guided design to create therapies aimed at tissue regeneration, inflammation resolution, and neural circuit restoration.

7 investors

Adaption Labs builds adaptive AI systems that continually learn and adjust to specific industries, languages, and use cases, positioning itself against large monolithic, one-size-fits-all models. Its work spans dynamically shaped datasets, gradient-free continual learning, and reimagined human-AI interfaces.

7 investors

Forerunner is a website template and creative engine designed for brands and creators to build portfolios, agency sites, and project launches with polished design systems and flexible components.

7 investors

Affinia Therapeutics develops genetically engineered adeno-associated virus (AAV) therapies for treating genetic diseases, focusing initially on cardiovascular and central nervous system conditions. The company uses AI and structural modeling to redesign viral delivery vectors for one-time-dose genetic medicines across rare and prevalent diseases.

7 investors

aiMotive develops automotive technology for level-agnostic automated driving, offering an integrated portfolio of tools and embedded solutions that enable rapid development and deployment of production autonomous driving features. The company serves automotive manufacturers and tier-1 suppliers seeking to reduce development costs and timescales.

7 investors

AIRY3D develops depth-sensing technology, including its DepthIQ system integrated onto CMOS image sensors, to give machines 3D perception. A spin-off of Montreal startup factory TandemLaunch, the company holds over 28 patents and serves customers across multiple industry verticals worldwide.

7 investors

Akselos provides SPM (Structural Predictive Maintenance) technology that models how operational decisions like ramp rates and startup/shutdown procedures affect stress, fatigue accumulation, and brittle fracture risk in refinery reactors. It serves petrochemical and refinery operators aiming to run faster cycles while maintaining structural integrity and uptime.

7 investors

Alice & Bob develops quantum computing hardware based on cat-qubit technology, building superconducting quantum chips and cryogenic systems aimed at error-corrected quantum computation. Its work includes multi-qubit chips with long bit-flip times and the development of logical qubits.

7 investors

Alljoined develops neural decoding technology using machine learning to enable computers to interpret human brain activity, aiming to enhance human capability, mental health, and interpersonal understanding. The company applies computational neuroscience to brain-computer interfaces for research and practical applications.

7 investors

Alta Resource Technologies develops engineered protein-based mineral separation technology to extract rare earth elements and critical minerals from mined ores, electronic waste, and processing byproducts. The company serves defense, electronics, semiconductors, energy, and recycling sectors, offering a domestically scalable alternative to traditional processing with higher selectivity and lower environmental impact.

7 investors