Deep Tech Startups

Alljoined develops neural decoding technology using machine learning to enable computers to interpret human brain activity, aiming to enhance human capability, mental health, and interpersonal understanding. The company applies computational neuroscience to brain-computer interfaces for research and practical applications.

5 investors

ALTR builds alcohol separation technology, including its Velvet Blade precision system, that lets beverage makers reduce the alcohol content of drinks such as wine while preserving flavor and sensory qualities. The company serves beverage producers looking to create lower-alcohol products.

5 investors

Alva Industries develops electric motors and drive systems using a patented FiberPrinting production technology for ironless, slotless stator windings, offering compact torque motors such as SlimTorq and GearTorq. The company targets electrification across multiple industries with a focus on high torque-density and lightweight motor designs.

5 investors

ANELLO Photonics develops silicon photonics-based inertial navigation systems, specifically its SiPhOG platform, which delivers optical gyroscope performance in a chip-scale form factor for GPS-denied environments. The company serves defense, autonomous systems, and commercial markets requiring resilient navigation in contested or GPS-denied conditions across land, air, and sea operations.

5 investors

Ansa provides an enzymatic DNA synthesis platform that directly synthesizes complex sequences up to 900 bp and delivers constructs up to 50 kb without assembly-based methods. It serves scientists in gene and cell therapies, antibody discovery, CDMOs, and agrigenomics.

5 investors

Anthro Energy develops advanced electrolytes and high-performance battery cells to improve energy density, safety, and form factor in battery technology. The company serves the electrification market and operates a production facility in California.

5 investors

Apollo is a venture capital firm that invests in life-science and biotechnology startups, combining entrepreneurial expertise with deep scientific knowledge to support early-stage companies in drug development and personalized medicine.

5 investors

Applied Brain Research develops state space models and edge AI hardware for real-time voice and sensor processing on devices without cloud connectivity. The company serves manufacturers of wearables, smart homes, AR glasses, robotics, and embedded systems across consumer and industrial sectors.

5 investors

Arm is a semiconductor company that designs and licenses processor IP and compute platforms used from edge devices to AI data centers, spanning markets such as data centers, automotive, and general computing. It is a publicly traded company majority-owned by SoftBank Group.

5 investors

Auki builds spatial computing technology that makes the physical world browsable, navigable, and searchable, with the goal of making physical spaces accessible to AI. Its work spans robotics capabilities including locomotion, manipulation, and perception (converting camera and sensor input into spatio-semantic observations).

5 investors

Auterion develops products and services around open standards for autonomous systems technology, contributing to open source projects and supporting academic institutions.

5 investors

Autobahn Therapeutics develops orally administered small molecule prodrugs using a brain-targeting chemistry platform to create regenerative medicines for central nervous system (CNS) disorders. The company targets both rare and prevalent brain diseases, using biomarker-driven development strategies to demonstrate on-target activity early in clinical trials.

5 investors

Avidity Biosciences develops Antibody Oligonucleotide Conjugates (AOCs) that combine monoclonal antibody specificity with oligonucleotide precision for targeted delivery of RNA therapeutics to treat rare genetic muscle diseases. The company has three clinical-stage programs targeting myotonic dystrophy type 1, facioscapulohumeral muscular dystrophy, and Duchenne muscular dystrophy.

5 investors

Axine Water Technologies develops electrochemical oxidation technology to destroy PFAS, pharmaceuticals, solvents, and other persistent organic contaminants in industrial wastewater. It offers a treatment-as-a-service model with on-site systems aimed at helping industrial operators meet wastewater compliance regulations.

5 investors

Azumo develops a low-power display technology called LCD 2.0 that maintains consistent contrast in both indoor and outdoor lighting. The displays are energy efficient to extend battery life and ultra-thin at 50µm, positioned as a component for device makers.

5 investors

Baebies develops multifunctional syndromic diagnostic testing using proprietary digital microfluidics, integrating molecular, immunoassay, chemistry, and coagulation testing into a single compact platform (FINDER) that runs on small-volume samples. Its products serve hospitals, clinics, pharmacies, and decentralized care settings for patients of all ages, having started with newborn and pediatric diagnostics.

5 investors

Big Hat Bio develops therapeutics under development across multiple programs. The company is a STEM-focused team working on therapeutic discovery and development.

5 investors

Blackshark.ai builds AI infrastructure that converts satellite and drone imagery into operational intelligence for understanding the physical world. The platform processes geospatial data at scale to enable applications including disaster response, infrastructure mapping, and training synthetic environments for autonomous systems.

5 investors

Blue Energy develops scalable small modular reactor (SMR) technology to deliver nuclear power at scale. The company focuses on removing economic barriers to nuclear infrastructure deployment for utilities and data centers seeking clean, reliable baseload energy.

5 investors

Broken String Biosciences develops tools for genome-wide on- and off-target analysis in gene editing, enabling in-house detection and characterization of gene editing-induced DNA breaks. It serves gene editing therapeutic developers working from discovery through IND across diverse cell types and nuclease systems.

5 investors

A New Zealand-based hydrogen technology company that manufactures Catalyst Coated Membrane (CCM) products for fuel cells with significantly reduced catalyst loading, enabling lower-cost production at scale.

5 investors

CADY provides AI-powered schematic analysis that reviews Netlist and BOM files to detect design flaws, errors, and best-practice violations in high-density PCB designs within minutes. It is aimed at hardware and electronics engineering teams working on complex circuit board designs.

5 investors

Cantos is a venture capital firm that provides pre-seed and seed capital plus ongoing counsel to founders building technology in areas such as abundance, resilience, and U.S. competitiveness. Its portfolio spans deeptech, defense, energy, space, robotics, and manufacturing companies.

5 investors

CarbonBridge develops a proprietary direct gas bioprocessing platform for bioreactor operations that eliminates solubility barriers without traditional equipment like spargers or agitators. The platform serves biotech and industrial biology companies seeking higher productivity and faster response times in bioprocessing.

5 investors