Deep Tech Startups

Origami Robotics develops hardware components, specifically gearboxes, to improve general-purpose robotic manipulation by addressing limitations of high-ratio designs in simulation-to-reality transfer and force feedback.

8 investors

Orum is a global biopharmaceutical company developing cancer therapies that combine protein degraders with antibodies. It focuses on Degrader Antibody Conjugate (DAC) technology to research and develop new therapeutics.

8 investors

P-1 AI builds Archie, an AI agent designed to function as a junior mechanical and electrical engineer that integrates into engineering teams and uses the same design tools as human engineers. It serves industrial companies, currently working with design partners in data center engineering (cooling, critical power) and expanding into automotive, aerospace, and defense.

8 investors

Parasail provides AI inference compute on a flexible fleet that scales with usage, letting companies commit to output (tokens) rather than long-term hardware purchases. It targets AI-native startups and builders that need production inference without multi-year silicon commitments.

8 investors

Portal Space Systems develops advanced spacecraft, including its flagship Supernova vehicle, designed for high delta-v maneuverability and multi-orbit operations in cislunar space. The company serves commercial and government customers seeking orbital transportation and refueling capabilities.

8 investors

Pow.Bio develops a high-efficiency continuous fermentation platform for biomanufacturing that enables production of biotech products at lower cost and faster timelines. The platform serves bioproduct manufacturers across synthetic biology, food, pharmaceuticals, and specialty chemicals.

8 investors

PRENAV uses drones, LiDAR, 3D analytics, and deep learning to automatically identify damage in infrastructure structures like bridges, dams, and cell towers. The company develops AI-powered inspection technology to make critical infrastructure assessment safer and more efficient.

8 investors

Prolific Machines licenses an optogenetics platform that adds light-based control to cell line development and GMP biomanufacturing, letting biopharma teams retrofit existing bioreactors and hosts to raise titers and manufacture complex molecule formats. It targets biopharmaceutical developers and manufacturers seeking higher productivity on difficult programs without re-platforming.

8 investors

Proteus Space designs custom spacecraft buses tailored to individual payload requirements using generative design and flight-proven components, eliminating the compromises of standardized bus solutions.

8 investors

Quantum Brilliance develops integrated quantum microchips based on diamond nitrogen-vacancy centers for sensing and computing applications. The company serves customers in power grid monitoring, materials research, healthcare imaging, autonomous vehicles, data centers, navigation systems, space operations, and cybersecurity.

8 investors

Quartzy provides lab management software for life science research labs, helping researchers organize and manage lab supplies and inventory. It also offers procurement for scientific research teams.

8 investors

Radical AI develops AI software that generates experimental designs for self-driving labs to accelerate materials discovery. The platform enables scientists to input performance goals and receive AI-optimized experiments that are tested and refined automatically, compressing the traditional materials research cycle from years to weeks.

8 investors

Rain AI develops energy-efficient hardware specifically designed for artificial intelligence workloads. The company serves AI model developers and data centers seeking power-optimized computing infrastructure.

8 investors

Reach Labs develops long-range wireless power networks aimed at providing scalable energy distribution infrastructure. The company works on wireless energy transmission technology.

8 investors

Reliable develops an autonomous flight control system that automates all phases of aircraft operation—taxi, takeoff, enroute, and landing—by adding high-integrity navigation, precision flight controls, secure communications, radar, and fault-tolerant compute to type-certified aircraft. Its aircraft- and airspace-agnostic system supports remote supervision from a control station for both commercial and military applications.

8 investors

Scope AR builds enterprise augmented reality tools that deliver real-time, step-by-step guidance to workers for tasks like remote support, employee training, equipment assembly, and maintenance and repair. It serves industrial and enterprise customers needing AR-based knowledge sharing and remote collaboration.

8 investors

Scout Space develops technologies for real-time sensing, data processing, and autonomous systems to protect space infrastructure. The company serves space operators and addresses safety and operational challenges in the space economy.

8 investors

Sentient Foundation is a non-profit organization committed to building open-source AGI independent of single-entity control. The organization serves researchers, engineers, artists, and academic institutions seeking to develop artificial general intelligence through collaborative, transparent, and open scientific approaches.

8 investors

Sila Nanotechnologies engineers next-generation battery materials, particularly silicon anodes, for use in electric vehicles, wearables, and other energy-intensive applications. The company develops advanced materials through its expertise in chemistry and material science, and operates manufacturing facilities to scale production globally.

8 investors

Space BD provides end-to-end support for space business, including satellite development and manufacturing, launch and deployment, on-orbit demonstration, and ground transport support. It also supports microgravity utilization for life science and materials R&D, and runs space-focused education and human-resource development programs for students and companies.

8 investors

Spartan, a radar technology brand of Pro-Vision, develops software-defined radar sensing and collision avoidance systems for commercial vehicle OEMs, Tier 1 suppliers, and fleet operators. Its systems target complex commercial environments such as mining, construction, material handling, and logistics.

8 investors

Standard Nuclear manufactures TRISO nuclear fuel for advanced reactors, establishing a domestic fuel supply chain for the nuclear energy sector in the United States. The company focuses on scaling advanced fuel production to support the deployment of next-generation nuclear power plants.

8 investors

Syenta develops high-resolution interconnect technology for chip-to-chip connections using Localized Electrochemical Manufacturing, enabling higher bandwidth between compute and memory in AI systems. The company targets semiconductor and AI hardware manufacturers with a manufacturing process designed for large-scale packaging.

8 investors

Transmutex develops accelerator-powered technology that converts nuclear waste into clean energy and produces medical radioisotopes. The company serves energy providers, waste management operators, and healthcare providers across the nuclear energy, waste management, and medical sectors.

8 investors