Deep Tech Startups

Simudyne builds simulation and agent-based modeling software that combines AI and machine learning to help organizations test decisions and drive growth. The company serves global banks, regulators, and exchanges.

2 investors

Singular Machines develops AI-native engineering tools for designing complex machines, facilities, and infrastructure in the advanced manufacturing sector.

2 investors

SiSaf is an RNA delivery and therapeutics company that uses its proprietary bioabsorbable silicon-based Bio-Courier technology to deliver nucleic acids, avoiding the ultra-cold supply chain of conventional lipid nanoparticles. It is developing a pipeline of RNA therapeutics targeting pancreatic cancer, metastatic cancer, and the rare skeletal disease osteopetrosis ADO2.

2 investors

SisuSemi provides an atomic-level purification process (ALP) that cleans and orders semiconductor wafer surfaces to remove atomic-scale contaminants and defects, targeting advanced nodes at 3 nm and below. The technology, aimed at semiconductor manufacturers, reduces defect density and leakage current to improve chip performance and manufacturing yield, and integrates into existing production lines.

2 investors

Site Bionics develops technology to enhance human experience by integrating physical-world tools with technology, allowing users to focus on human interactions. The company operates across multiple domains to improve how people interact with their physical environment.

2 investors

SIXAI is a system integration company that embeds advanced technologies and artificial intelligence into legacy industrial sectors. Its portfolio includes MAESTRO, a centralized control tower for coordinating indoor and outdoor floor operations, and Powermat, a wireless power/inductive charging technology developer.

2 investors

Skapion develops a native counter-swarm air defense platform that integrates detection, interception, and command-and-control into a distributed, mobile architecture for intercepting multiple simultaneous aerial threats. The system is aimed at protecting allied military forces across domains.

2 investors

Skorpios Technologies manufactures photonic integrated circuits and provides foundry services for silicon photonics. The company serves telecommunications, data center, and high-speed optical communication markets.

2 investors

Skouria applies geothermal engineering principles to develop hydrometallurgical systems for mineral extraction. The company uses stimulation and lixiviant technologies to engineer subsurface reservoirs for mining operations.

2 investors

Skycharge builds an automatic, programmable charging system for drones, consisting of a charge source and sink with power-line communication, along with contact-based docking solutions like TILES and BOLO S1. Its hardware is engineered and manufactured in Germany for drone platform operators.

2 investors

Skyfora develops weather forecasting technology using AI-driven GNSS tomography and GPS-based radiosondes to close gaps in weather data. The company works at the intersection of atmospheric science and AI to support climate change adaptation.

2 investors

Skykraft provides air traffic management services delivered via satellite, including voice and data communications, surveillance, and positioning services for aviation over remote and oceanic regions.

2 investors

Skyports develops and operates the world's first commercial vertiport network for urban air mobility. The company builds integrated infrastructure in urban centers and creates operational ecosystems around them, working with regulators and city partners.

2 investors

SkyServe provides edge computing and AI model management software for satellite operators to deploy AI-powered earth observation applications on satellites. The platform reduces latency, downlink costs, and data processing demands for geospatial analytics providers and government organizations.

2 investors

smallTalk develops technology products that support early childhood brain development through language exposure. The company targets parents and caregivers of infants and young children in the early development market.

2 investors

SmartCatch develops compact microfiltration devices that isolate Circulating Tumor Cells (CTCs) directly from whole blood without pre-analytical steps, enabling liquid biopsy for cancer diagnosis and monitoring. Its products target clinicians, pharmaceutical companies, and researchers in medical oncology and precision medicine.

2 investors

Smarter Alloys develops Multiple Memory Material technology, a platform based on shape memory alloys that enables devices to function with previously inaccessible capabilities across medical, wearable, and industrial applications. The company serves manufacturers and product designers seeking lighter, more reliable, and smarter materials solutions.

2 investors

Soctera develops nitride semiconductor power amplifiers that use a thinner semiconductor stack to deliver higher power density and lower operating temperatures for 5G telecom, SATCOM, and radar systems. Spun out of Cornell University's School of Electrical and Computer Engineering, the company targets telecommunications, radar, electronic warfare, and satellite communication networks.

2 investors

SOINN develops compact, low-computation AI based on its patented "artificial brain SOINN" technology to add intelligence to devices, equipment, and information systems. Its recent focus areas include energy management, anomaly detection, and control of equipment and robots for business clients.

2 investors

Solaires develops next-generation solar cells through a team of scientists, engineers, and business professionals. The company focuses on solar cell technology within the clean energy sector.

2 investors

SOLATOM designs and manufactures modular linear Fresnel solar concentrators for research and industrial applications, enabling companies to generate high-temperature thermal energy from concentrated solar for process heat and hybrid industrial boiler systems.

2 investors

Soley Therapeutics develops proprietary imaging, AI, and automation technology to analyze cellular responses to stress and drug exposure, enabling the discovery of novel medicines and therapeutic mechanisms.

2 investors

Solgate is a drug discovery company developing small-molecule drugs that target solute carrier (SLC) membrane transporter proteins, using a platform combining chemical, biological, and computational technologies. A spin-off from CeMM/ÖAW and IST Austria, it focuses on advancing a pipeline of SLC-targeting compounds toward clinical development for human disease.

2 investors

Soliddd is an optical and vision technology company developing a low-vision aid for people with macular degeneration, using autostereo 3D optics that let the visual cortex perceive 3D to restore sight in previously blind areas of the visual field. The product is in pre-clinical testing and targets patients with macular degeneration and other vision conditions.

2 investors