Deep Tech Startups

SemiProbe develops wafer and device characterization systems, including the Probe System for Life (PS4L), for semiconductor manufacturers and research labs.

2 investors

Semron develops 3D CapRAM, a semiconductor technology that performs computing inside 3D flash memory by stacking many layers on silicon, aimed at meeting the compute demands of AI workloads.

2 investors

SENISCA is a University of Exeter biotech developing RNA-based senotherapeutics that target dysregulated RNA splicing to reverse cellular senescence and treat age-related disease. Its work centers on modulating RNA biology to address the molecular mechanisms driving cellular ageing.

2 investors

Sensetics develops digital touch technology using programmable fabric with metamaterials and piezoelectrics to capture and replay tactile sensations in real time. The company serves roboticists, automation operators, and users of virtual environments who need tactile feedback and sensory integration.

2 investors

Sensibel designs and manufactures studio-quality optical MEMS microphones for portable devices, professional audio equipment, and microphone array applications. The company offers the SBM100B series with superior dynamic range, signal-to-noise ratio, and distortion performance alongside evaluation kits for integration and testing.

2 investors

Senslytics provides an AI platform that uses explainable machine learning to predict and prevent equipment failures in the oil and gas industry. The platform helps engineers and energy professionals optimize maintenance decisions by identifying root causes and reducing costly unplanned downtime.

2 investors

Sensmore builds Machine Assist, a physical AI system that gives drivers of heavy machinery real-time situational awareness and collision warnings for people, other machines, and static objects. It combines 4D radar, physical AI, and RTK GNSS localization in a hardware kit aimed at industrial and mining operations.

2 investors

Sensoteq manufactures Kappa X, a wireless vibration sensor that monitors rotating machinery across industries by collecting vibration, temperature, and speed data with high-bandwidth capability for early fault detection.

2 investors

Sentea commercializes silicon photonics-based fiber optic sensor technology and interrogators, originating from over a decade of research at Ghent University's Photonics Research Group and imec. The company serves applications requiring advanced optical sensing capabilities.

2 investors

Sentieon develops optimized bioinformatics algorithms for genomic data processing, particularly for precision medicine applications. The company specializes in variant calling and other secondary analysis tools that process next-generation sequencing data.

2 investors

Septhom is developing a relationship-focused artificial general intelligence, based on scientific and technological research, aimed at improving how people connect with one another and with intelligent systems.

2 investors

Seraphim is a specialist investor in space technology companies, operating across the full funding lifecycle from early-stage through IPO. The firm backs SpaceTech founders developing technologies for global security, infrastructure resilience, and sustainability challenges.

2 investors

Serif Biomedicines develops DNA-based therapies and nucleic acid delivery technologies for genetic medicine. The company aims to create tailored, long-acting treatments across multiple diseases.

2 investors

SFC Energy AG manufactures fuel cells, power supplies, and power management systems for clean energy, defense, and industrial applications. The company operates across clean energy solutions, tactical power systems, and semiconductor/laser power supplies from headquarters in Germany.

2 investors

ShanX Medtech develops a diagnostic platform that identifies bacterial infections and determines antibiotic susceptibility from patient samples within approximately one hour. The system serves clinicians in hospital microbiology labs and point-of-care settings, providing targeted treatment guidance based on individual patient needs.

2 investors

Shearwater Aerospace develops intelligent drone systems designed for public safety, disaster response, and other applications where traditional aircraft use is costly or risky. The company's Smart Flight platform aims to enable faster, longer-range uncrewed operations while reducing greenhouse gas emissions compared to conventional aviation.

2 investors

ShineMed pursues a step-by-step commercialization approach to fusion energy, aiming to prove market value at each stage while generating revenue toward the goal of clean, abundant fusion power.

2 investors

Sift is an end-to-end platform for teams building advanced hardware that consolidates sensor and telemetry data into a single system for analysis, anomaly detection, and automated test rule evaluation. It offers sub-second anomaly detection, fault-tree investigation on a shared timeline, audit-ready certification reports, and multiple deployment models with built-in security.

2 investors

Signum Technologies develops artificial intelligence and computer vision solutions in collaboration with U.S. National Laboratories and Federal Agencies to address critical challenges in healthcare, security, and national defense. The company commercializes advanced biosensor and imaging technologies originally developed for urgent public health and security needs.

2 investors

Silent Ventures is an early-stage venture capital firm that invests in founders building aerospace, defense, and national security companies. The firm focuses on concept-stage pre-seed and seed investments in the defense technology sector.

2 investors

Silicon Line designs and manufactures semiconductor ICs and optical sub-assemblies for high-speed data transmission in cables and display systems. The company serves device makers and manufacturers across consumer electronics, professional imaging, and automotive applications.

2 investors

SMG develops high-precision resonant MEMS inertial and gravity sensors, including accelerometers, gyroscopes, and the GAIA gravity system, spun out from Cambridge University research. Its sensors serve autonomous navigation, aerospace, defence, robotics, and geophysics/subsurface exploration applications.

2 investors

SimpleRose is a high-performance computing optimization company developing Rose, a parallel optimization engine for solving large-scale mixed-integer programming (MIP) problems. It parallelizes the entire solving process—branching, cuts, and heuristics—across CPUs and GPUs to give enterprises faster solve times on larger, more complex optimization problems.

2 investors

Altair leverages high-performance computing and data science to solve complex engineering and scientific challenges for customers across industries. The company was acquired by Siemens, the leading industrial software company.

2 investors