Deep Tech Startups

Edgeforce develops advanced military and security technology aimed at upgrading the capabilities of the country's security and armed forces.

1 investor

Edison.ai develops AI and blockchain technology solutions for enterprises and society. The company operates in generative AI (LLM and image generation), custom AI services with big data and image analysis, Web3/blockchain solutions (NFT, DAO, DeFi), and cashierless retail systems powered by computer vision.

1 investor

EditCo manufactures arrayed CRISPR guide RNA libraries for functional genomics screening, using its proprietary XDel technology to achieve high-efficiency gene knockouts in human and mouse cell lines. The company serves research institutions and biotech companies conducting target discovery and validation studies.

1 investor

EdotEnv is a quant research lab building reinforcement-learning environments at scale from financial market data, designed to increase in difficulty so AI agents can continuously improve. It works with frontier AI labs and academic groups on research harnesses, evaluation benchmarks, and post-training environments toward recursive self-improvement.

1 investor

EFI is a medical technology and device company developing haptic-feedback technology for laparoscopic minimally invasive surgery, using patented optical and strain-gauge sensors to give surgeons tactile and force feedback on tissue stiffness and arterial pulsations. Its instruments include the OptiGrip (undergoing CE certification) and the OptiTouch, and it is also developing robotic applications.

1 investor

Egra.ai develops Reinforcement Learning from Biofeedback (RLBF), pairing EEG with other biosignal modalities to convert involuntary human brain responses into reward signals for training AI models. It is building a foundation model that maps multimodal biosignals to error and preference signals across text, audio, and video, along with the hardware and pipeline to feed these signals into AI labs' post-training stacks.

1 investor

Eikonizo develops small molecule therapeutics targeting neurodegenerative and cardiorenal diseases. The company is focused on creating novel, disease-modifying treatments to improve patient outcomes.

1 investor

EikoSim provides Digital Image Correlation (DIC) technology that bridges physical testing and finite element simulation by directly mapping displacement and deformation measurements onto computational meshes. The solution serves engineering teams in manufacturing and research who need to validate and refine simulation models with high-resolution experimental data.

1 investor

Eka Robotics develops general-purpose robotics powered by a single AI model designed to generalize across objects, tasks, and environments, with an emphasis on physical reliability and safe collaboration alongside humans. The company applies techniques such as self-supervised learning, large-scale robot learning, world models, reinforcement learning, and sim-to-real robotics.

1 investor

Ekidna develops a lab-on-a-chip system for rapid, decentralized testing of cannabinoids, using electrochemical sensors to detect compounds in various sample types. It serves cannabis growers and product manufacturers.

1 investor

EkoScan Integrity develops non-destructive testing (NDT) products and infrastructure monitoring technology, offered as a service to assess the performance and reliability of physical assets and infrastructure.

1 investor

eLab4Space develops data compression algorithms and software-defined satellite solutions for space missions. The company serves space agencies and operators by reducing communication overhead and improving data analytics in remote satellite configurations.

1 investor

Elcyo develops a "Fresnel liquid crystal lens" — a thin, large-aperture liquid crystal lens with adjustable focus — to build wide field-of-view autofocus eyeglasses. The company positions this as consumer eyewear based on its liquid crystal lens technology, with product sales planned for around autumn 2027.

1 investor

ELDIM Technologies develops measurement systems for aerospace and avionics applications, including display analysis, LIDAR, and laser measurement tools that support compliance and research across production and laboratory environments.

1 investor

Element Materials Technology provides materials testing, product qualification, and assurance services for customers in aerospace, space, defense, and energy sectors. The company operates two global business lines and serves highly regulated industries.

1 investor

Elev8 is a venture capital firm that invests in and partners with early-stage startups in next-generation computing, green materials and climate, smart mobility, and medical technology.

1 investor

ElFys manufactures ultra-sensitive photodetectors based on patented Black Silicon technology, serving medical device makers, analytical instrument producers, and defense sectors across more than 20 countries.

1 investor

EligoChem is a drug discovery company staffed by directors with expertise in medicinal and computational chemistry, biology assay development, and screening.

1 investor

Synera provides agentic AI software that executes directly on engineering data (CAD, CAE, PLM, ERP) for automotive OEMs, tier-one suppliers, and large manufacturers. The platform automates repetitive engineering workflows while maintaining security, logging, and engineer approval requirements, enabling faster design iterations and cost reduction.

1 investor

Ellis Bio develops genomic and epigenetic analysis technologies for research and diagnostics, leveraging proprietary RNA and DNA methylation research. The company serves biotech and pharmaceutical organizations seeking advanced sequencing and detection capabilities.

1 investor

Elm Street Ventures is a seed and early-stage venture capital fund that invests in startups with a Yale University connection, typically commercializing research licensed from Yale, as well as companies in the greater New Haven area. Its portfolio spans therapeutics, industrial tools and materials, and climate-focused interventions.

1 investor

Elodin provides a cloud-based simulation platform for building autonomous systems, targeting developers and engineers creating satellites, drones, and robots. The company aims to make advanced autonomy tooling accessible and affordable to innovators in aerospace and robotics.

1 investor

A Korean company that develops inspection and measurement instruments along with AI machine vision products. The page shown is an investor relations / electronic disclosure section.

1 investor

Embedd provides software enablement for semiconductors by modeling chips as digital twins and deterministically generating software, tests, and simulations. It targets developers and hardware teams building on silicon.

1 investor