Deep Tech Startups

DENKweit develops vision AI technology for industrial quality and data management applications. The company, a Fraunhofer spin-off based in Germany, builds image analysis systems designed to be accessible and deliver practical value across industries.

1 investor

DeNoize develops active noise-cancellation window technology that uses adaptive sound monitoring to reduce urban noise in residential spaces. The company serves homeowners and properties affected by environmental noise, operating in the acoustic comfort and sustainable building technology sector.

1 investor

DenovAI Biotech uses artificial intelligence and computational molecular biophysics to design proteins de novo, building platforms for rapid antibody discovery and bespoke high-affinity binders. The company targets therapeutic and diagnostic applications, including antibodies, peptide biologics, and diagnostic reporters for drug discovery.

1 investor

Denovo Sciences develops an AI platform for structure-based small-molecule drug discovery, using generative algorithms to design candidate molecules de novo within a target's binding pocket and predict their synthesizability and drug-likeness. It runs its own drug discovery programs and partners with others to identify small-molecule drug candidates, including work on broad-spectrum influenza inhibitors.

1 investor

Deorbital Devices provides space logistics services including satellite last-mile delivery, orbital transportation, hosted payload operations, mission control, and space waste management, using a proprietary orbital transfer vehicle. It targets satellite operators and the broader space economy with in-orbit transportation and infrastructure.

1 investor

Deployable Energy builds the Unity Nuclear Battery, a compact, modular, transportable 1 MW microreactor system that provides continuous clean power. It targets industrial, defense, humanitarian, and remote applications, and is preparing an initial reactor demonstration at Idaho National Laboratory.

1 investor

Desentum is a clinical-stage biopharmaceutical company developing allergen immunotherapy products that reprogram immune responses to allergens toward tolerance. The company targets both respiratory and food allergies, with its lead asset currently in phase II clinical trials.

1 investor

D2S develops GPU-accelerated computing and deep learning technologies for semiconductor manufacturing, focusing on curvilinear mask data preparation and inverse lithography. Its products support photomask production and lithography workflows in the semiconductor industry.

1 investor

Detail Earth provides high-resolution aerial imagery, down to 5 cm resolution with vertical and oblique views updated three times a year, accessible on any device. It includes AI-based measurement tools, 3D visualization, map editing, and an AI copilot for turning imagery into insights.

1 investor

D&I Solutions develops technology to detect and interdict unauthorized wireless communications, targeting contraband cell phone use by inmates in correctional facilities. The system focuses on identifying and blocking unauthorized cellular calls made from within prisons.

1 investor

Detraxi is a privately held company developing emerging technology, seeking development funding and licensing partnerships. The page provides limited detail about the specific product or industry.

1 investor

DEVAR develops AI-powered augmented reality technology, including a platform that generates AR experiences, 3D models, and interactive content from text descriptions, and a Large Geospatial Model for spatial mapping and persistent AR content placement. It serves creators, brands, and enterprises across sectors such as retail, education, manufacturing, marketing, arts, and architecture.

1 investor

Dewpoint Innovations develops functional nanostructured polymeric surfaces for atmospheric water capture, technology originating from PhD research at the University of Sydney. The company applies surface coating and materials science to sustainable water-generation and climate technologies.

1 investor

Dexlabs is an engineering design and manufacturing services firm offering product design, 3D modeling, rapid prototyping via 3D printing, additive manufacturing, and injection molding design. It works with startups and large enterprises across industries such as consumer electronics to take ideas from concept to full-scale production.

1 investor

DGG builds RapidPipeline, software for automating 3D content pipelines that lets companies process and optimize 3D models as easily as 2D images. It serves studios, brands, retailers, and platform companies for digital production and marketing workflows.

1 investor

Hologic Diagenode provides epigenomics profiling services and sample preparation products for next-generation sequencing, proteomics, and epigenetics research. It serves biomarker discovery and validation through epigenomics and bioinformatics for research applications.

1 investor

Diamante develops plant-based compounds for therapeutic and diagnostic systems targeting autoimmune diseases. The company applies molecular farming techniques to produce biopharmaceuticals and aims to advance treatments from research to clinical applications.

1 investor

Diamidex develops rapid microbial detection and enumeration methods for laboratories, covering pathogens such as Legionella pneumophila, E. coli, coliforms, and Pseudomonas aeruginosa. Its solutions deliver results in colony forming units up to five times faster than standard methods while reducing labor time.

1 investor

Diamond Foundry manufactures lab-grown single-crystal diamond, including diamond wafers, with a vertically integrated approach spanning reactor and process technology in its own foundries. Its output spans consumer diamond jewelry (via its VRAI unit) and semiconductor applications, positioning diamond as a material foundation for AI chips, datacenters, and electric cars.

1 investor

DIAS Infrared manufactures pyrometers, thermal imaging cameras, and software solutions for non-contact temperature measurement in industrial production and quality assurance processes. The company serves manufacturing and automation industries with tools for thermal inspection, weld monitoring, and automated temperature data capture.

1 investor

DigiChem operates an AI-native platform for on-demand custom molecule synthesis, letting users design and order molecules online and access process and analytical data. It serves innovators needing specialty chemicals from lab scale to production, with manufacturing in the USA.

1 investor

digiLab provides an AI platform called the Uncertainty Engine that helps organizations and governments tackle complex, high-stakes challenges by combining machine learning with uncertainty quantification for safer, more explainable decision-making. The platform is purpose-built for safety-critical domains including advanced energy, critical infrastructure, cybersecurity, and environmental conservation.

1 investor

Digital Biology (Digit Bio) develops precision biologics and combination therapies for solid tumors, using its M×P (Molecules × Phenotypes) Platform that combines high-resolution imaging, next-generation sequencing, computation, and AI to map the spatial molecular organization of tumor tissues. The company applies this measurement technology to discover spatially synergistic tumor antigen targets for immunotherapies and partners with pharmaceutical companies and foundations in precision oncology.

1 investor

Digitais provides predictive and prescriptive analytics and AI-based solutions, including computer-vision condition monitoring, for structural integrity management in the oil and gas industry. Its risk-based tools aim to optimize resource allocation, reduce downtime, and extend the life of aging assets.

1 investor