Deep Tech Startups

Planckian develops foundational technology for large-scale quantum computers, building a quantum processor that combines superconducting circuits with a new approach to qubit control for scalability. The company operates in the quantum computing hardware space.

2 investors

Plasmion develops mass spectrometry technology, including an industrial sensory system for real-time in-line analysis of volatile organic compounds (VOCs) and a universal ion source for laboratory analysis. It serves industrial and laboratory customers across analytical chemistry applications.

2 investors

Plastometrex builds the PLX-Benchtop, a non-destructive mechanical testing machine that extracts metal stress-strain curves and strength properties (yield strength, UTS) from a small surface indentation using its PIP (Profilometry-based Indentation Plastometry) method. It serves materials engineers as an alternative to slow or impractical tensile testing, with users including NASA, Airbus, and additive manufacturing OEMs.

2 investors

Poetiq builds self-improving AI systems that sit on top of existing LLMs to extract and synthesize their embedded knowledge into reliable reasoning strategies, using far less data than traditional reinforcement learning post-training. The systems are aimed at businesses seeking to solve practical, real-world reasoning problems and workflows.

2 investors

POLARISqb combines quantum computing, genetics, and molecular chemistry to design novel drugs for previously undruggable diseases. The company targets pharmaceutical development using advanced computational methods to accelerate drug discovery.

2 investors

Poly6 develops additive manufacturing solutions for complex industrial processes in the aviation and energy sectors. The company emerged from MIT research and focuses on advancing manufacturing technology for aerospace and energy applications.

2 investors

Portal Biotech develops bench-top instruments that use nanopore biosensors coupled with machine learning to detect, sequence, and characterise single protein and metabolite molecules, revealing modifications, mutations, and isoforms. The technology, spun out of the Maglia Lab at the University of Groningen, serves academic research, biopharmaceutical, biotechnology, and industrial labs for proteomic and metabolomic analysis.

2 investors

Proto develops holographic display hardware and software that turn physical or existing digital displays into interactive AI agents. Its platform targets spatial AI and real-time human interaction use cases.

2 investors

Positrigo develops functional imaging technology to make diagnostic and clinical imaging scalable and accessible globally. The company serves researchers and clinicians who use imaging for disease diagnostics, treatment monitoring, and therapeutic development.

2 investors

Powerhouse.bio is a biotechnology company that combines experimental biology with applied machine learning. The company works at the intersection of biology and computational science.

2 investors

PowerPhotonic designs and manufactures wafer-scale freeform optics, including beam shapers, diffusers, homogenizers, and combiner optics, for engineers building advanced laser systems. It serves markets such as industrial laser processing, ophthalmology, laser displays, and defence, offering both standard products and bespoke design and manufacturing services.

2 investors

PowerSpin develops spintronics-based power semiconductors and high-efficiency power electronics technology, offering intellectual property licensing, circuit designs, and consulting services.

2 investors

PPO develops hyperspectral imaging and AI-based systems for real-time food assessment and quality control, helping food producers detect contaminants and reduce food waste. The company serves food processing facilities in North America with technology that reads food chemistry and chemistry to improve safety and sustainability.

2 investors

ProtaGene provides molecular bioanalytical services for gene therapy development, specializing in biodistribution studies, transgene expression assessment, and vector shedding analysis to support preclinical safety evaluation and clinical development of viral vector-based therapies.

2 investors

Alluris manufactures force and torque testing and measurement devices for industrial applications. The company serves diverse industrial sectors with precision testing instruments and offers calibration and maintenance services.

2 investors

Pramatra Space develops satellite-based quantum key distribution (QKD) systems using integrated photonics chips to deliver encryption keys to enterprises. The company provides quantum cryptography solutions designed to protect digital assets against ransomware and future quantum computing attacks.

2 investors

Prazer Therapeutics develops therapeutics using Targeted Protein Degradation (TPD) technology, including its SPiDEM platform, in which small molecules selectively bind pathological proteins and activate the ubiquitin-proteasome system for their elimination. The company's pipeline focuses on treatments for viral infections and associated diseases as well as other refractory conditions.

2 investors

Precision Microbubbles develops the M Sorter, a benchtop device that purifies commercially available microbubble suspensions into uniform-sized populations for scientific and medical applications. The device is designed for researchers and clinicians who require consistent, monodisperse microbubbles without complex synthesis processes.

2 investors

Preferred Networks vertically integrates computer science technologies from semiconductors and computing infrastructure to solutions and applications, developing AI/machine learning systems including the domestically-built large language model PLaMo and the MN-Core AI processor series. The company works with leading firms in industrial robotics, pharmaceuticals, energy, and other sectors to apply advanced computing technology in real-world applications.

2 investors

Prefrontal develops frontier AI models aimed at automating scientific discovery.

2 investors

Primrose Bio develops high-efficiency production systems for innovative and complex biologics, using advanced protein expression and enzyme engineering technologies deployed across commercially proven platforms. The company serves pharmaceutical developers and contract manufacturers in the biopharmaceutical industry.

2 investors

Principle Power provides technology and engineering services for floating offshore wind turbines, enabling wind farms to be deployed in deep water and challenging seabed conditions worldwide. The company develops and commercializes its patented WindFloat product portfolio for developers, utilities, and power producers pursuing renewable energy generation.

2 investors

Prism ML develops compact large language models that run locally on consumer devices; its Bonsai 27B model supports multi-step reasoning, tool calling, agentic workflows, and multimodal understanding on phones and laptops. The models come in 1-bit (3.9GB, phone-capable) and Ternary (5.9GB, laptop-optimized) variants.

2 investors

Process Vision develops optical measurement and imaging technology for the oil and gas industry, focused on improving process efficiency, reducing maintenance costs, and lowering emissions. The company serves operators and producers in the energy sector with advanced analytical instrumentation.

2 investors