Deep Tech Startups

Diamond Foundry manufactures lab-grown single-crystal diamond, including diamond wafers, with a vertically integrated approach spanning reactor and process technology in its own foundries. Its output spans consumer diamond jewelry (via its VRAI unit) and semiconductor applications, positioning diamond as a material foundation for AI chips, datacenters, and electric cars.

1 investor

DIAS Infrared manufactures pyrometers, thermal imaging cameras, and software solutions for non-contact temperature measurement in industrial production and quality assurance processes. The company serves manufacturing and automation industries with tools for thermal inspection, weld monitoring, and automated temperature data capture.

1 investor

DigiChem operates an AI-native platform for on-demand custom molecule synthesis, letting users design and order molecules online and access process and analytical data. It serves innovators needing specialty chemicals from lab scale to production, with manufacturing in the USA.

1 investor

digiLab provides an AI platform called the Uncertainty Engine that helps organizations and governments tackle complex, high-stakes challenges by combining machine learning with uncertainty quantification for safer, more explainable decision-making. The platform is purpose-built for safety-critical domains including advanced energy, critical infrastructure, cybersecurity, and environmental conservation.

1 investor

Digital Biology (Digit Bio) develops precision biologics and combination therapies for solid tumors, using its M×P (Molecules × Phenotypes) Platform that combines high-resolution imaging, next-generation sequencing, computation, and AI to map the spatial molecular organization of tumor tissues. The company applies this measurement technology to discover spatially synergistic tumor antigen targets for immunotherapies and partners with pharmaceutical companies and foundations in precision oncology.

1 investor

Digitais provides predictive and prescriptive analytics and AI-based solutions, including computer-vision condition monitoring, for structural integrity management in the oil and gas industry. Its risk-based tools aim to optimize resource allocation, reduce downtime, and extend the life of aging assets.

1 investor

Digital Anatomics manufactures personalized surgical guides for tibial osteotomy procedures used to correct knee deformities and potentially delay joint replacement. The company serves orthopedic surgeons and surgical centers with custom-made Class IIa medical devices tailored to individual patient anatomy.

1 investor

Dimenco develops a platform combining spatial AI software and switchable-display hardware that enables immersive content experiences on standard consumer devices without requiring new hardware. The platform allows users to view movies, images, and social media with lifelike holographic depth effects on phones, tablets, monitors, and laptops.

1 investor

Diptera.ai uses proprietary optics, computer vision, and automation to scale the sterile insect technique (SIT) for mosquito control, releasing sterile males to suppress mosquito populations. It targets municipal and commercial customers seeking eco-friendly alternatives to pesticides.

1 investor

Dirac Labs develops GPS-free quantum navigation systems that use the Earth's crustal magnetic signatures to determine location in environments where GPS is unavailable, such as underwater, underground, or indoors. The systems are designed to be passive, precise, and secure.

1 investor

Disarray builds AI research agents for long-horizon autonomy over heterogeneous data, helping practitioners automate tedious ML development tasks while maintaining control over high-judgment decisions. The company combines deep systems research with production ML expertise to create autonomous agents that track context, reuse prior work, and sustain open-ended experimental loops.

1 investor

Discovery Loop builds AI systems that automate the experimental loops of scientific and engineering research, using frontier AI models and large-scale computing to propose, run, and learn from thousands of experiments in parallel. The company is initially focused on automating machine learning research and engineering before expanding to other science and engineering domains.

1 investor

Dispatch Bio develops a universal immunotherapy treatment for solid tumors, combining engineered immunotherapy with a tumor-specific virus to improve cancer treatment outcomes.

1 investor

Distran manufactures ultrasonic (acoustic) cameras that detect and locate pressurized gas leaks from a distance for industrial operators in sectors such as oil and gas, chemical, and power generation. Its handheld and fixed monitoring products support leak detection, methane emission reduction, and safety inspections in hazardous environments.

1 investor

Howso (formerly Diveplane) builds understandable, explainable AI that lets users make decisions directly from data instead of relying on black-box neural networks, and offers an open-source engine. It serves researchers, academics, non-profits, financial enterprises, healthcare organizations, and government agencies.

1 investor

Divitel provides AI-driven operational intelligence and autonomous operations management for telecom operators and media companies managing video and broadband networks. The company leverages proprietary platforms, real-time data pipelines, and domain-trained AI models built on 25+ years of operational expertise.

1 investor

Dognosis builds "olfaction AI" that pairs trained biomedical detection dogs with a non-invasive canine brain-computer interface and machine learning to identify disease-associated volatile organic compounds in breath samples. Its breath-based screening is aimed at early, multi-cancer detection and produces a VOC risk score for clinicians.

1 investor

Dutscher provides after-sales service (SAV) and post-delivery support (SAL) for laboratory equipment and consumables, handling warranty claims, non-warranty repairs, maintenance, product returns, and transport damage resolution.

1 investor

DotBlocks develops a cloud-based numerical simulation platform for solving fluid dynamics and thermal problems using advanced methods like lattice Boltzmann modeling. The platform serves industrial R&D teams and researchers who need to run complex transient simulations and parametric studies.

1 investor

Dotphoton develops image compression and processing software that lets teams acquire, store, and manage large volumes of high-quality RAW images and generate synthetic data for machine learning. It serves industrial customers in fields such as automotive, space, and life sciences.

1 investor

DotX Automation develops intelligent robotic systems and automation solutions for the robotics industry, combining artificial intelligence, hardware design, and systems integration.

1 investor

Dotz develops graphene and carbon-based nanomaterials combined with detectors, a mobile app, and cloud software for product authentication, traceability, and anti-alteration, and is building sorbent technology for CO₂ capture. It serves brand security, ESG, and industrial applications across a range of industries.

1 investor

DphiSpace operates OmniSat, shared satellite platforms with onboard compute servers that host third-party hardware sensor payloads and run software workloads in orbit. It serves organizations needing space-based hosting for hardware and software, having flown its first demonstration mission, Clustergate-1, in March 2025.

1 investor

Draper is a venture capital firm that invests in startups across AI and robotics, Bitcoin and blockchain, precision medicine and longevity, aerospace and space infrastructure, and frontier deeptech. Its portfolio spans automation, decentralized finance, AI-driven diagnostics, and space technology.

1 investor