Deep Tech Startups

Activate builds community and programs to help scientists and engineers commercialize breakthrough research into real-world solutions. The organization supports science entrepreneurs through fellowship programs, mentorship, and networks that connect them with funding and resources to navigate from laboratory discovery to market impact.

2 investors

Active Needle Technology develops active (vibrating) needle technology to improve ultrasound-guided needle interventional procedures. The company operates in the medical device sector, focusing on ultrasound devices and piezoelectric materials.

2 investors

AcuraStem is a biotechnology company developing antisense oligonucleotide treatments for neurodegenerative diseases such as ALS and frontotemporal dementia, using its iNeuroRx technology platform for disease modeling and drug discovery. It targets PIKFYVE, discovered by its co-founders, to advance a pipeline of therapies.

2 investors

AcuSurgical develops robotic systems for vitreoretinal ophthalmic surgery, enabling surgeons to perform complex microsurgeries with enhanced precision and control. The company serves ophthalmic surgeons and patients requiring retinal procedures.

2 investors

Oorstec (Guangdong Oorstec Micro-Nano Technology) develops a digital microfluidics platform based on proprietary active-pixel thin-film semiconductor arrays that generates and manipulates large numbers of microscale biological droplets in parallel. Its technology serves life-science research, enabling high-throughput screening, discovery, and functional studies at the single microbe, cell, and molecule level.

2 investors

Cascade is an AI coordination platform for architecture, engineering, and construction firms that automates business development by analyzing unstructured project opportunities, scoring them for firm fit, and streamlining the pursuit-to-delivery cycle. The platform learns from each customer interaction to improve recommendations and turns the construction industry's relationship-driven sales process into a systematic, data-driven approach.

2 investors

QDi.AC is a quantum diamond atomic clock component that provides frequency reference and timing stability for electronic systems requiring long-term clock accuracy without external signals. It targets precision timing applications in GPS receivers, navigation systems, telecommunications infrastructure, and autonomous sensor networks.

2 investors

Adamo Foods develops meat alternatives using a proprietary fermentation technology, producing fungi-based (mycelium) steaks and fillets. The company sells its plant-based products to restaurants.

2 investors

ADAXION develops deimmunized biologic therapies using its ADAx platform, which incorporates proprietary CD22 ligands to eliminate therapeutic-specific B cells and reduce anti-drug antibody responses. The company focuses on enabling biotherapeutics that would otherwise face prohibitive immunogenicity.

2 investors

Additive Drives manufactures high-performance, additively (3D) printed electric motors that avoid rare-earth materials while achieving high efficiency and thrust-to-weight ratios. The German company serves industrial and blue-chip customers in areas such as e-mobility, robotics, aerospace, and energy-intensive applications like data centers.

2 investors

ADTechnology provides semiconductor services including turnkey solutions (SCM, test packaging, OSAT partnerships), SoC and chip design services across legacy and advanced processes, IP support, and an ADP platform that lets fabless companies internalize part of their design work. It serves fabless semiconductor customers and chip product developers.

2 investors

Advanced Photonix develops optoelectronic components and solutions for high-volume manufacturing, leveraging manufacturing facilities in India and Malaysia and deep expertise in optoelectronics engineering.

2 investors

Advertent Biotherapeutics is a biotechnology company developing first-in-class biologics that modulate TGF-β family growth factors to protect muscle quality and promote regeneration in neuromuscular disorders, with a particular focus on muscular dystrophies. Founded in 2019 as a spin-out from Michigan State University, it targets high-unmet-need conditions where muscle degeneration and wasting cause disability.

2 investors

Adverum is a clinical-stage gene therapy company developing Ixo-vec, an investigational single-administration intravitreal treatment for wet age-related macular degeneration and other ocular diseases, based on a proprietary adeno-associated virus (AAV) vector platform. Its therapies aim to transform retinal cells into biofactories that continually produce anti-VEGF protein, reducing the need for frequent eye injections.

2 investors

Advion Interchim Scientific provides laboratory instruments, consumables, reagents, and software for chemical analysis and purification tasks such as chromatography, mass spectrometry, and ICP-MS. The company serves life science researchers and laboratories globally with identification, quantification, and purification solutions.

2 investors

AEInnova builds self-powered industrial IoT sensors that harvest waste heat to wirelessly monitor vibration and temperature on rotating machinery and high-temperature processes, paired with a cloud platform (DAEVIS) for predictive maintenance. It serves heavy industries such as oil & gas, steel, cement, paper, plastics and chemicals.

2 investors

Aeolus develops hardware and software aimed at reducing weather-related risk, with initial products focused on mitigating the impact of hurricanes and severe storms through reconstructed models of the physical world. It operates in the climate and weather-risk technology space.

2 investors

AEPONYX develops photonic integrated circuits and related microfabrication technologies for telecommunications and data communication applications.

2 investors

Aerogen develops aerosol drug delivery systems for hospital and ICU use, enabling targeted delivery of proteins, peptides, and solutions to the lungs. The company is a global leader in ventilator-based aerosol drug delivery for critical care settings.

2 investors

Aerospec develops AIRMon, an automated instrument for real-time chemical analysis of aerosol particulate matter using FTIR technology. The solution serves environmental monitoring agencies, industries, research groups, and public health organizations to identify pollution sources and track air quality.

2 investors

Aevo Loop develops chemical building blocks based on dicarboxylic acids that enable plastic polymers to be easily recycled and composted while maintaining structural integrity. The company's materials use oxygen-based linking units to create engineering plastics designed for circular economy manufacturing at scale.

2 investors

AgTech Inventures is an agriculture technology innovation lab that develops intellectual property in agbiotech and precision agriculture, sourcing promising technologies from university research labs and small science-focused companies. It spins these technologies into new companies with input from industry partners, leading initial management teams and helping secure both non-dilutive and angel/venture financing.

2 investors

Applied General Intelligence builds AI infrastructure centered on a Language Compiler Model (LCM) designed for deterministic, explainable outputs without hallucinations, plus an Agentic Marketplace Platform (AMP) for matching and executing transactions on complex assets. It targets high-reliability enterprise and mission-critical environments requiring understanding, reasoning, verified identity, and execution.

2 investors

AI Fabrik builds modular inference infrastructure for enterprise AI workloads, designed to enable real-time AI deployment at scale with low latency and cost efficiency across distributed sites.

2 investors