AI & Machine Learning Startups

Shortwave builds an AI-first communications app designed for effective human-AI collaboration, starting with email. The platform aims to deliver significant productivity gains by giving users AI access to their business communications data while maintaining user control.

4 investors

Shuttle is an open source cloud platform for developing and deploying web applications with Rust, replacing container technology with a lightweight alternative to achieve sub-second deploy times. It targets backend developers seeking faster development cycles and simplified cloud infrastructure management.

4 investors

Sidecar provides an AI system that automates repetitive manual workflows in logistics operations, including quote requests, job file creation, data entry, and financial reconciliation. The platform integrates with existing tools and systems used by freight forwarders, supply chain companies, and logistics providers.

4 investors

Sieve provides a data quality platform that combines AI and human validation to clean and verify financial datasets for investment teams. The company serves asset managers, hedge funds, investment banks, family offices, and other financial institutions seeking to reduce time and cost spent on data validation and remediation.

4 investors

Sieve creates high-quality multimodal datasets and training environments for frontier AI labs developing generative media, robotics, and agentic systems. The company combines exabyte-scale infrastructure with novel data collection and processing techniques to serve AI research teams and enterprise customers.

4 investors

Sift Biosciences develops T-cell immunotherapies for cancer and autoimmune diseases, using an AI-driven discovery platform combined with metagenomics and high-throughput cellular screening to identify microbially derived molecules that activate memory T cells. Its SIFT platform supports pipelines in oncology and autoimmunity, with the latter partnered with a large pharmaceutical company.

4 investors

Siftly tracks brand visibility across AI platforms like ChatGPT, Gemini, and Perplexus, generates optimized content for AI search results, and measures revenue impact. The platform serves companies in software, services, healthcare, fintech, e-commerce, and wellness seeking to improve their presence in generative AI responses.

4 investors

Currence (Sightline Climate) offers a data platform that pairs an AI data engine with expert analysts to turn thousands of sources into proprietary data, models, and forecasts on energy and climate technology. It serves power and utility leaders, developers, investors, and founders, delivering insights via platform, API, or embedded workflows.

4 investors

Sigma Computing provides a warehouse-native analytics platform that lets business teams build, deploy, and govern AI applications on live data warehouse data without moving it, using spreadsheet-style input tables, embedded agents, and automated actions. It serves enterprise data, finance, and operations teams building self-service dashboards and workflow apps.

4 investors

Sigma360 builds risk intelligence software that combines global data, entity resolution, and matching to deliver financial crime, credit risk, and decisioning solutions. It serves financial services, corporates, and professional services firms, supporting AML screening, monitoring, KYC, KYB, and CDD compliance.

4 investors

SiLC Technologies develops silicon photonics-based 4D+ vision systems for autonomous machines and robots. The company delivers integrated chip-scale vision solutions for industrial automation, robotics, mobility, and security applications.

4 investors

Silicon Data provides real-time price transparency and GPU performance data, along with GPU rental indices and forward curves, treating AI compute as a tradable commodity. It serves traders, financial institutions, and builders navigating compute markets.

4 investors

SilkChart analyzes B2B SaaS sales calls to measure playbook adoption and sales rep performance, surfacing coaching opportunities and actionable feedback to improve deal outcomes. The platform automatically scores calls against proven sales methodologies and provides AI-generated coaching feedback without requiring manual input.

4 investors

Acoustic is a marketing platform that helps lifecycle marketers understand consumer intent and execute campaigns faster through an Intent-Driven Model powered by first-party behavioral data and AI. The company serves marketing teams looking to move beyond legacy MarTech stacks toward real-time customer engagement.

4 investors

SiMa.ai designs silicon and software to enable machine learning inference at the edge, deployed in industrial, automotive, and autonomous systems rather than cloud environments. The company serves manufacturers, vehicle makers, and equipment operators requiring low-latency AI processing on physical machines.

4 investors

Simbian builds an AI-driven security operations (SecOps) platform that uses autonomous AI agents to investigate alerts, run threat hunts, conduct penetration tests, and manage network and firewall operations for enterprise and MSSP security teams. The platform is designed to defend against AI-powered cyberattacks while automating existing SOC workflows.

4 investors

SimBioSys builds AI-powered 3D visualization and diagnostic technology that models tumors as "digital twins" to support individualized cancer treatment planning. Its tools serve breast cancer surgeons and clinicians for preoperative planning and analysis in oncology.

4 investors

Similarweb provides web analytics showing traffic market share across mobile, desktop, and tablet platforms, including device traffic trends and top platforms by country. It serves businesses analyzing digital audience and regional traffic data.

4 investors

Simmunome provides computational biology and mechanistic modeling solutions for drug development across all phases, helping pharmaceutical companies understand disease pathways, validate drug targets, predict efficacy, and optimize patient stratification.

4 investors

simpleclub is an AI-supported learning platform for vocational training, continuing education, and retraining, offering content aligned with IHK curricula, exam preparation, learning management tools, and a content creator. It serves companies and education providers to train apprentices and skilled workers, with a focus on Germany.

4 investors

SimplicityDX provides infrastructure that extracts data from creator content and product recommendations to help brands win visibility with AI-powered search engines and shopping bots across social media and modern purchase paths. The platform serves eCommerce brands navigating the shift from keyword search to AI-mediated discovery.

4 investors

Simplified offers Riley, an AI marketing assistant that plans, creates, publishes, and reports on marketing content, with the user approving work before it ships. It targets founders and lean teams who want to run marketing without hiring a dedicated team.

4 investors

Simpplr provides an employee experience platform that consolidates internal communications, information sharing, and collaboration tools into a single workspace, helping organizations improve employee engagement and productivity across distributed teams.

4 investors

Simundia offers professional coaching for companies through its Coaching Situationnel method, delivering remote one-hour sessions (3 or 6) in which a coach helps employees observe, reflect, and act to change behaviors and build skills. It provides an HR dashboard that aggregates coaching impact via self-assessment and 360 interviews to measure organizational transformation.

4 investors