AI & Machine Learning Startups

Sidecar provides an AI system that automates repetitive manual workflows in logistics operations, including quote requests, job file creation, data entry, and financial reconciliation. The platform integrates with existing tools and systems used by freight forwarders, supply chain companies, and logistics providers.

4 investors

Sieve creates high-quality multimodal datasets and training environments for frontier AI labs developing generative media, robotics, and agentic systems. The company combines exabyte-scale infrastructure with novel data collection and processing techniques to serve AI research teams and enterprise customers.

4 investors

Sift Healthcare builds RevProtect, a predictive analytics platform that helps health systems anticipate reimbursement denials and optimize revenue cycle management before claims are submitted. The platform integrates clinical context and payer response patterns to deliver role-specific actions embedded in existing workflows.

4 investors

Siftwell is a healthcare technology company founded by former health plan operators and clinicians that applies data analytics and operational expertise to improve managed care organization (MCO) operations and member outcomes.

4 investors

Signos is a metabolic health platform that pairs a continuous glucose monitor (CGM) with an AI-powered app to help consumers understand how food, movement, and daily habits affect their glucose and to support weight management. The membership includes CGM hardware, registered dietitian support, and real-time guidance based on glucose data and meal/workout logs.

4 investors

Signpost provides AI-powered customer communication and lead management for home service businesses across HVAC, plumbing, electrical, roofing, and related trades. The platform combines AI voice receptionists, live receptionists, and automated texting to capture and respond to customer inquiries across multiple channels including phone, text, Angi, Thumbtack, and Facebook.

4 investors

Silimate builds AI-powered EDA software that accelerates chip design workflows by combining fast computation engines, machine learning models, and user-friendly interfaces. The platform serves SoC and IP companies in hardware design by functioning as a copilot to help chip designers understand design tradeoffs and iterate faster.

4 investors

Similarweb provides web analytics showing traffic market share across mobile, desktop, and tablet platforms, including device traffic trends and top platforms by country. It serves businesses analyzing digital audience and regional traffic data.

4 investors

Simply is an app that teaches music (piano, guitar, drawing) and creative skills to learners worldwide using real-time adaptive feedback.

4 investors

SimplyWise builds AI-powered apps for small business owners that automate administrative tasks such as construction cost estimating, receipt tracking, call handling, and mileage capture. Its tools aim to help business owners generate bids and manage business records.

4 investors

Simpplr provides an employee experience platform that consolidates internal communications, information sharing, and collaboration tools into a single workspace, helping organizations improve employee engagement and productivity across distributed teams.

4 investors

SimScale provides a cloud-based simulation platform that combines computational fluid dynamics, finite element analysis, thermal, and electromagnetics capabilities with AI-powered tools for engineers. The platform enables engineering teams to rapidly test design options and make decisions without requiring specialized CAE expertise or dedicated hardware.

4 investors

Sinumy develops hands-free authentication technology, described as a first-of-its-kind in Japan and globally. The company builds this deeptech recognition/authentication technology and pursues partnerships and new business ventures around it.

4 investors

Sirona Medical builds RadOS, a cloud-native platform that reimagines radiology practice in the AI age for physicians and radiology practices. The platform consolidates radiology workflows and leverages artificial intelligence to advance patient care delivery.

4 investors

Sixfold provides an AI-powered underwriting platform for insurance carriers, MGAs, and reinsurers to automate and accelerate the underwriting process. The platform processes submissions across multiple business lines and continents, enabling underwriters to focus on complex decisions while AI handles routine work.

4 investors

4 investors

Skipify builds payments infrastructure and checkout technology for merchants, aiming to improve the payment experience across digital commerce. The company connects directly to major financial networks to enable faster, more secure transactions.

4 investors

SkyLink is an AI-powered chat-based corporate travel booking platform that enables users to book flights and hotels in seconds through conversational interfaces while automatically applying company travel policies and preferences. It serves enterprise travel managers and business travelers seeking faster bookings, policy compliance, and real-time cost optimization.

4 investors

Slamcore develops embedded software that uses multi-sensor data fusion and SLAM algorithms to enable machines and robots to understand and navigate their environment. The software serves OEMs and manufacturers building autonomous systems across industrial, logistics, and robotics applications.

4 investors

Sleek provides AI agents that understand and interact with webpages to help users find and apply coupons, view cashback deals, and access product-level pricing information across millions of retailers. The platform serves digital commerce platforms, browser extensions, and app builders seeking to monetize through deal discovery and cashback rewards.

4 investors

Slope provides a B2B payments platform that enables businesses to accept payments and offer financing, with a focus on digitizing the order-to-cash process for online commerce. The company uses generative AI to modernize traditionally manual B2B payment workflows.

4 investors

Smack builds domain-specific AI models for military decision-making. The company serves defense and military organizations across branches including the Air Force, Navy, Marines, and Special Operations Command.

4 investors

JustPark Insights is a parking data platform that centralizes information from equipment, payments, and applications to provide real-time visibility into parking metrics. It enables parking operators to optimize occupancy, pricing, and revenue through business intelligence and automated reporting.

4 investors

Smarsh provides AI-powered platform for capturing, archiving, and analyzing regulated communications data to help financial institutions meet compliance requirements and uncover business intelligence. The company serves financial institutions and other regulated enterprises needing to manage communications data across email, chat, voice, video, and other channels.

4 investors