Samir Kaul
InvestorFounderManaging Director at Khosla Ventures · Board director at Mariana Minerals · Board director at Traba · Board director at Ukko
Menlo Park, California
Writes $500K – $50M checks · typically $25M
About
Samir Kaul led an early, outsized bet called the first and largest check into OpenAI and applies genomics experience from Craig Venter’s Institute to evaluating biotech, health and deep-tech.
Likely emails· guessed from name + firm domain, not firm-published
- s•••@khoslaventures.comreveal100% confident
- s•••@khoslaventures.comreveal90% confident
- s•••@khoslaventures.comreveal80% confident
- s•••@khoslaventures.comreveal70% confident
Invests in
AI & Machine LearningBiotechCleantechClimate TechDeep TechEnterprise SoftwareHealthtech
Beyond investing
- Founded
- He co-founded Helicos BioSciences with Stanford's Stan Lapidus and Steve Quake, a company developing single-molecule sequencing instruments. He was the founding CEO of Codon Devices, raising its Series A financing and building its technical and advisory teams.
- Education
- Studied at University of Michigan Studied at Harvard Business School (MBA)
- Boards
- He is a board member and chair of the Development Committee of UCSF Benioff Children's Hospital. He joined the Board of Directors of The Michael J. Fox Foundation in 2025. He was a longtime member of the Nominating and Leadership Committees of the Tipping Point Community, a nonprofit focused on poverty alleviation in the Bay Area. He served on the board of trustees for the U.S. Ski and Snowboard Association. He serves on the Dean's Cabinet of Harvard's School of Engineering and Applied Sciences.
- Charities
- He is a founding donor to the Elevate Campaign for the Yellowstone Club Community Foundation. He endowed the directorship of the Michigan Institute for Computational Discovery and Engineering at the University of Michigan. He established a Professorship of Biomedical Innovation and Translation between Harvard Medical School and Harvard Business School.
- Communities
- He remains deeply involved with his alma maters, the University of Michigan and Harvard University. He has expressed deep loyalty to the University of Michigan, from celebrating football championships to funding a new AI institute at the school.
- Hobbies
- He is dedicated to health optimization and sleep fitness, frequently posting his own recovery statistics from devices like Whoop and Eight Sleep.
- More
- He led the Arabidopsis Genome Initiative at Craig Venter's Institute for Genomic Research and published seven peer-reviewed papers in genomics, including a landmark Nature paper on the first complete genome of a flowering plant (Arabidopsis thaliana, 2000). He has backed repeat founder Gilad Almogy across four different companies.
From Samir's own website — common ground for a warm intro.
Board director at Mariana Minerals
Intro paths
In turn, Samir can intro founders to Mariana Minerals's investors below.
Mariana Minerals's investors · 8
Co-founders at Mariana Minerals

Board director at Traba
Intro paths
In turn, Samir can intro founders to Traba's investors below.
Traba's investors · 6
Co-founders at Traba
Board director at Ukko
Intro paths
In turn, Samir can intro founders to Ukko's investors below.
Ukko's investors · 7
Co-founders at Ukko
Experience
- Khosla VenturesFounding General Partnercurrent2006 — present
- ReevoBoard Membercurrent2024 — present
- PrimerInvestorcurrent2021 — present
- Fortera CorporationBoard Membercurrent2019 — present
- RightwayBoard Membercurrent2021 — present
- TrabaBoard Membercurrent2022 — present
- HeadspaceBoard Membercurrent2023 — present
- Varda Space IndustriesBoard Membercurrent2021 — present
- FulfilBoard Membercurrent2020 — present
- StatespaceBoard Membercurrent2020 — present
- Scipher MedicineBoard Membercurrent2018 — present
- RaxiumInvestorcurrent2017 — present
- MirvieBoard Membercurrent2018 — present
- Eligo BioscienceInvestorcurrent2017 — present
- UkkoBoard Membercurrent2017 — present
- Siolta TherapeuticsBoard Membercurrent2017 — present
- Mojo Vision Inc.Investorcurrent2017 — present
- CodaInvestorcurrent2015 — present
- CadreInvestorcurrent2015 — present
- Iora HealthInvestorcurrent2015 — present
- Guardant HealthBoard Membercurrent2014 — present
- Oscar HealthInvestorcurrent2013 — present
- Impossible FoodsBoard Membercurrent2013 — present
- QuantumScapeInvestorcurrent2010 — present
- Mainspring EnergyBoard Membercurrent2010 — present
- Flagship VenturesPartner2002 — 2006Cambridge, MA
Education
- Harvard Business SchoolMaster of Business Administration - MBA2000 — 2002
- University of MarylandMaster of Science - MS, Biochemistry1995 — 1997
- University of MichiganBachelor's degree, Biology1991 — 1995
Skills & more
+3 more
Business StrategyExecutive ManagementMergers & AcquisitionsLanguages English · French · Hindi
From Samir's professional profile.
Deals · 5
TrabaLed round
via Khosla Ventures · filed Jun 2022
Impossible FoodsLed round
via Khosla Ventures · filed Mar 2020
HookLed round
via Khosla Ventures · filed Aug 2017
Guardant HealthLed round
via Khosla Ventures · filed Dec 2014
NutanixLed round
via Khosla Ventures
Attribution from SEC filings, press coverage, and firm rosters.
Other disclosed investments
Led
Connie HealthGranularIora HealthMainspringMirvieNanoH2OOpenAIOscar HealthPrimerQuantumScapeRaxiumReevoRhodaRightway HealthSLDSplit PayUltima GenomicsVarda Space Industries
Investor
EpitomeLS9Morphotek
Sources: the firm's website · curated public sources.
Colleagues at Khosla Ventures
Network2
Investors connected to Samir in public investor directories — a warm-intro map.
Frequently asked questions
- Who is Samir Kaul?
- Samir Kaul led an early, outsized bet called the first and largest check into OpenAI and applies genomics experience from Craig Venter’s Institute to evaluating biotech, health and deep-tech.
- Where does Samir Kaul work?
- Samir Kaul is Managing Director at Khosla Ventures and Board director at Mariana Minerals and Board director at Traba and Board director at Ukko.
- What does Samir Kaul invest in?
- Samir Kaul invests in AI & Machine Learning, Biotech, Cleantech, Climate Tech, Deep Tech, Enterprise Software, Healthtech.
- What check size does Samir Kaul write?
- Samir Kaul typically writes checks of $500K – $50M.
- What companies has Samir Kaul invested in?
- Investments tracked here include Connie Health, Granular, Guardant Health, Hook, Impossible Foods, Iora Health, Mainspring, Mirvie, NanoH2O, Nutanix, OpenAI, Oscar Health, and 14 more.
- Where did Samir Kaul go to school?
- Samir Kaul studied at Harvard Business School (Master of Business Administration - MBA); University of Maryland (Master of Science - MS, Biochemistry); University of Michigan (Bachelor's degree, Biology).
- Does Samir Kaul lead rounds?
- Yes — Samir Kaul has led 23 tracked investments.
Same school
Also attended Harvard Business School1,977
+ 1,971 more
Also attended University of Maryland205
+ 199 more
Also attended University of Michigan492
+ 486 more





















































