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Luca Pegolotti

Founder

Founder at Nucleo

Zürich Metropolitan Area

FoundedNucleo · YC

Find your path to Luca

1,469 people in our graph share verified history with Luca — schools, employers, funds. One of them is your warm intro.

Paul KwanunlockedLuca: together at Stanford University (2021–2023)
Luca: together at Stanford University
Luca: together at Stanford University Graduate School of Business
×8Luca: together at Y Combinator

About

Luca Pegolotti holds a BSc from Politecnico di Milano and an MSc and PhD from EPFL, with research experience at Stanford School of Medicine. He previously worked on physics-informed machine learning at Apple Health AI, focusing on computational methods and AI applications in healthcare.

Founder at NucleoYC F25

Intro paths

YC

Luca went through Y Combinator (Fall 2025) — any YC alum in your network can reach them through the YC community.

GP

Their group partner at YC was Nicolas Dessaigne, General Partner at Y Combinator — the partner who ran Nucleo's batch and knows the company first-hand. YC profile ↗

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In turn, Luca can intro founders to Nucleo's investors below.

Nucleo's investors · 4

6th Man VenturesNew York · $2M – $5M checksBain Capital CryptoSan FranciscoLombardstreet VenturesWoodside · $500K checksY CombinatorSan Francisco · $500K checks · since 2025

Co-founders at Nucleo

AIAngelica Iacovelli
Angelica IacovelliFounder

Experience

  1. Nucleo (YC F25)Co-founder & CTOcurrent2025 — presentSan Francisco, CA
  2. ApplePostdoctoral Researcher2023 — 2025Zurich, Switzerland
  3. SiemensSoftware Development Intern2016Munich, Bavaria, Germany
  4. EPFL (École polytechnique fédérale de Lausanne)Teaching Assistant2015

Skills & more

C++Matlab12Python7Java6C2LaTeX2MATLAB2Machine Learning1Artificial Intelligence (AI)1Mathematics10Algorithms8Numerical Analysis5
+5 moreSoftware DevelopmentMathematical ModelingResearchMathematical ModellingComputational Mathematics

Languages English · French · German · Italian

  • Stanford Ignite – Part-Time — Stanford University Graduate School of Business

From Luca's professional profile.

Frequently asked questions

Who is Luca Pegolotti?
Luca Pegolotti holds a BSc from Politecnico di Milano and an MSc and PhD from EPFL, with research experience at Stanford School of Medicine. He previously worked on physics-informed machine learning at Apple Health AI, focusing on computational methods and AI applications in healthcare.
Where does Luca Pegolotti work?
Luca Pegolotti is Founder of Nucleo.
What companies did Luca Pegolotti found?
Luca Pegolotti founded Nucleo.
Where did Luca Pegolotti go to school?
Luca Pegolotti studied at Stanford University (Postdoc); Y Combinator (Founder (YC F25)); EPFL (Doctor of Philosophy - PhD, Mathematics).

Founder mafias

Same school

Shared employers

Also worked at Nucleo (YC F25)1

Angelica IacovelliFounder at Nucleo