Where does Luca Pegolotti work?

Luca Pegolotti is Founder of Nucleo.

Where did Luca Pegolotti go to school?

Luca Pegolotti studied at Stanford University (Postdoc); Y Combinator (Founder (YC F25)); EPFL (Doctor of Philosophy - PhD, Mathematics).

Luca Pegolotti

Founder

Founder at Nucleo

Zürich Metropolitan Area

FoundedNucleo · YC

About

Luca Pegolotti holds a BSc from Politecnico di Milano and an MSc and PhD from EPFL, with research experience at Stanford School of Medicine. He previously worked on physics-informed machine learning at Apple Health AI, focusing on computational methods and AI applications in healthcare.

Founder at Nucleo YC F25

Intro paths

Luca went through Y Combinator (Fall 2025) — any YC alum in your network can reach them through the YC community.

Their group partner at YC was Nicolas Dessaigne, General Partner at Y Combinator — the partner who ran Nucleo's batch and knows the company first-hand. YC profile ↗

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In turn, Luca can intro founders to Nucleo's investors below.

Nucleo's investors · 4

6th Man VenturesNew York · $2M – $5M checks Bain Capital CryptoSan Francisco Lombardstreet VenturesWoodside · $500K checks Y CombinatorSan Francisco · $500K checks · since 2025

Co-founders at Nucleo

Angelica IacovelliFounder

Experience

Nucleo (YC F25)Co-founder & CTOcurrent2025 — presentSan Francisco, CA
ApplePostdoctoral Researcher2023 — 2025Zurich, Switzerland
SiemensSoftware Development Intern2016Munich, Bavaria, Germany
EPFL (École polytechnique fédérale de Lausanne)Teaching Assistant2015

Skills & more

C++Matlab12Python7Java6C2LaTeX2MATLAB2Machine Learning1Artificial Intelligence (AI)1Mathematics10Algorithms8Numerical Analysis5

+5 more

Software DevelopmentMathematical ModelingResearchMathematical ModellingComputational Mathematics

Languages English · French · German · Italian

Stanford Ignite – Part-Time — Stanford University Graduate School of Business

From Luca's professional profile.

Frequently asked questions

Who is Luca Pegolotti?: Luca Pegolotti holds a BSc from Politecnico di Milano and an MSc and PhD from EPFL, with research experience at Stanford School of Medicine. He previously worked on physics-informed machine learning at Apple Health AI, focusing on computational methods and AI applications in healthcare.
Where does Luca Pegolotti work?: Luca Pegolotti is Founder of Nucleo.
What companies did Luca Pegolotti found?: Luca Pegolotti founded Nucleo.
Where did Luca Pegolotti go to school?: Luca Pegolotti studied at Stanford University (Postdoc); Y Combinator (Founder (YC F25)); EPFL (Doctor of Philosophy - PhD, Mathematics).

Founder mafias

Y Combinator mafia8,773

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Sam AltmanPresidentFounded Tools for Humanity +3 Jessica LivingstonCo-founderFounded Y Combinator Alexis OhanianYC Summer 2005Founded Reddit Fred EhrsamYC Summer 2012Founded Nudge +1 Matt HuangYC Winter 2011Founded Hotspots Trae StephensYC Winter 2022Founded Pursuit +1

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Y Combinator mafia4,716

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Ryan SheaEntrepreneurshipFounded Stacks Tarek MansourFounded Kalshi Suhail DoshiEating beans & riceFounded Playground +1 Subomi OluwalanaW22Founded Convoy Darius "Bubs" MonsefS19Founded Sightbox +3 Matthew ScholzFounded Oisin Biotechnologies +3

+ 4,709 more

Stanford University mafia903

Also came through, then founded or led a company.

Peter ThielJ.D.Founded PayPal +1 Reid HoffmanB.S.Founded LinkedIn +2 Joe LonsdaleBSFounded Opto +3 Mike Maples JrBSFounded Pattern Breakers Steve JurvetsonMSEEFounded Mojo Vision Balaji SrinivasanGraduate StudentFounded Counsyl +1

+ 896 more

Stanford University Graduate School of Business mafia267

Also came through, then founded or led a company.

Steve JurvetsonMaster of Business Administration (MBA)Founded Mojo Vision Tony XuMBAFounded DoorDash David VélezMBAFounded Nubank Matt RouifStanford Ignite (Summer Institute for Entrepreneurship)Founded Photoroom +3 IanMaster of Business Administration (M.B.A.)Founded Immunity Project +2 Mikhail KokorichStanford Executive ProgramFounded Destinus +2

+ 260 more

EPFL mafia55

Also came through, then founded or led a company.

Raquel UrtasunDoctor of Philosophy - PhDFounded Waabi Steve AnaviMaster of Science (MSc)Founded Qonto Ravi JainInternshipFounded Genylabs +1 Veronica Gambillara FonckPhDFounded LimmaTech Biologics +1 Anna VybornovaMaster's degreeFounded Polari Group +1 Toni RosinolBachelor of ScienceFounded Stack AI +1

+ 48 more

Same school

Also attended Stanford University2,000

Peter ThielCo-founder & Partner at Founders Fund Reid HoffmanCo-founder of LinkedIn; Partner at Greylock David SacksCo-founder & General Partner at Craft Ventures; former White House AI & Crypto Czar Keith RaboisManaging Director at Khosla Ventures Garry TanPresident & CEO of Y Combinator Alfred LinPartner at Sequoia Capital

+ 1,994 more

Also attended Y Combinator2,000

Tarek MansourCo-founder & CEO of Kalshi Suhail DoshiFounder of Mixpanel; founder of Particle Subomi OluwalanaCo-founder & CEO of Convoy Arhaan A.Deeptech Fellow at Clear Ventures Maroof AhmedFounder at Octopus Ventures Justin SwartPartner at Bitkraft Esports Ventures

+ 1,994 more

Also attended Stanford University Graduate School of Business1,519

Roelof BothaAdvisor & former Steward at Sequoia Capital; SpaceX board member Peter FentonGeneral Partner at Benchmark Steve JurvetsonCo-founder of Future Ventures David SzeAdvisory Partner at Greylock Katherine BoyleGeneral Partner at Andreessen Horowitz (American Dynamism)Hunter WalkCo-founder & Partner at Homebrew

+ 1,513 more

Also attended Politecnico di Milano121

Riccardo MontiOperating Advisor at P101 Ventures Giuseppe LacerenzaPartner at Keen Venture Partners Walter PaleariInvestment at Makers Fund Lorenzo ThioneGeneral Partner at Gaingels Agustina Soriano SergiSenior Associate — Ventures at Energize Ventures José GuardoInvestment & Product Intern at Kibo Ventures

+ 115 more

Shared employers

Also worked at Nucleo (YC F25)1

Angelica IacovelliFounder at Nucleo

Also worked at Apple508

Reid HoffmanCo-founder of LinkedIn; Partner at Greylock Jim BreyerFounder & CEO of Breyer Capital Daniel GrossMeta Superintelligence Labs; co-founder of NFDG and Safe Superintelligence Steve JurvetsonCo-founder of Future Ventures Kai-Fu LeeChairman of Sinovation Ventures and CEO of 01.AI Steve WozniakCo-founder of Apple

+ 502 more

Also worked at Siemens251

Karim FarisInvestor at GV (Google Ventures)OttoInvestor at Investinor Celine XiaoInvestor at DN Capital Bala SathiamurthyInvestor at IVP (Institutional Venture Partners)GiselaInvestor at Eudemian Ventures Thomas MeierPartner, Head of Resilience in Energy & Resources Investments at Verve Ventures

+ 245 more

Also worked at EPFL (École polytechnique fédérale de Lausanne)63

Raquel UrtasunFounder & CEO of Waabi Bouraux LeopoldAI & Data Engineer at Newfund Capital Christoph FreiPartner, Head of Energy at Emerald Technology Ventures Ag Yannick RitschelInvestor at Backbone Ventures Christian JaagBoard Member at CV VC Kylee MuriClient Relations Associate at WestCap

+ 57 more

About

Founder at NucleoYC F25

Intro paths

Nucleo's investors · 4

Co-founders at Nucleo

Experience

Skills & more

Frequently asked questions

Founder mafias

Y Combinator mafia8,773

Y Combinator mafia4,716

Stanford University mafia903

Stanford University Graduate School of Business mafia267

EPFL mafia55

Same school

Also attended Stanford University2,000

Also attended Y Combinator2,000

Also attended Stanford University Graduate School of Business1,519

Also attended Politecnico di Milano121

Shared employers

Also worked at Nucleo (YC F25)1

Also worked at Apple508

Also worked at Siemens251

Also worked at EPFL (École polytechnique fédérale de Lausanne)63

Founder at Nucleo YC F25