Nucleo
YC F25San Francisco, US · Founded 2025 · 2 employees · 4 known investors
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2,057 people in our graph share verified history with the Nucleo team — schools, employers, funds. One of them is your warm intro.
Paul Kwanunlockedknows Luca Pegolotti · together at Stanford University (overlapped)
knows the team · via Stanford University
knows the team · via Stanford University Graduate School of Business
×4knows the team · via Universidad Complutense de Madrid
×2knows the team · via Y Combinator
knows the team · via Università Cattolica del Sacro Cuore
Nucleo automates CT scan analysis for oncology care, providing AI-powered tools for tumor lesion sizing, body composition assessment, and lesion classification to support clinical workflows in hospitals.
Founders & leadership· Y Combinator alumni (F25)
Nucleo was founded in 2025 by Angelica Iacovelli and Luca Pegolotti.
AI
Angelica Iacovelliin𝕏CEO, Co-founderShe previously conducted research at Stanford University on cardiovascular modeling and fluid dynamics simulation, with contributions to NVIDIA's scientific computing libraries. She holds a BS and MS in Mathematical Engineering from Politecnico di Milano and completed a research exchange at IIT Madras.
LP
Luca PegolottiinCo-founder & CTOLuca Pegolotti holds a BSc from Politecnico di Milano and an MSc and PhD from EPFL, with research experience at Stanford School of Medicine. He previously worked on physics-informed machine learning at Apple Health AI, focusing on computational methods and AI applications in healthcare.
Investors · 4
Funding
SEC filings, press & company announcements- Undisclosed amountseedNov 2022Source ↗
Source: company announcements and press reports — follow each round's link for the claim.
In the news
Frequently asked questions
- What does Nucleo do?
- Nucleo automates CT scan analysis for oncology care, providing AI-powered tools for tumor lesion sizing, body composition assessment, and lesion classification to support clinical workflows in hospitals.
- Who founded Nucleo?
- Nucleo was founded by Angelica Iacovelli, Luca Pegolotti in 2025.
- Who are Nucleo's investors?
- Nucleo's investors include Y Combinator, 6th Man Ventures, Bain Capital Crypto, Lombardstreet Ventures.
- Where is Nucleo headquartered?
- Nucleo is headquartered in San Francisco, US.