Fundraising Fox

Nucleo

YC F25

Founded 2025 · 2 employees · 4 known investors

Nucleo automates CT scan analysis for oncology care, providing AI-powered tools for tumor lesion sizing, body composition assessment, and lesion classification to support clinical workflows in hospitals.

Founders & leadership· Y Combinator alumni (F25)

Nucleo was founded in 2025 by Angelica Iacovelli and Luca Pegolotti.

AIAngelica Iacovelli
Angelica Iacovelliin𝕏CEO, Co-founderShe previously conducted research at Stanford University on cardiovascular modeling and fluid dynamics simulation, with contributions to NVIDIA's scientific computing libraries. She holds a BS and MS in Mathematical Engineering from Politecnico di Milano and completed a research exchange at IIT Madras.
LPLuca Pegolotti
Luca PegolottiinCo-founder & CTOLuca Pegolotti holds a BSc from Politecnico di Milano and an MSc and PhD from EPFL, with research experience at Stanford School of Medicine. He previously worked on physics-informed machine learning at Apple Health AI, focusing on computational methods and AI applications in healthcare.

Investors · 4

In the news

Frequently asked questions

What does Nucleo do?
Nucleo automates CT scan analysis for oncology care, providing AI-powered tools for tumor lesion sizing, body composition assessment, and lesion classification to support clinical workflows in hospitals.
Who founded Nucleo?
Nucleo was founded by Angelica Iacovelli, Luca Pegolotti in 2025.
Who are Nucleo's investors?
Nucleo's investors include Y Combinator, 6th Man Ventures, Bain Capital Crypto, Lombardstreet Ventures.