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Jacob Smith

Investor

Partner at Cannage Capital · Principal at 11.2 Capital

San Francisco, California

Writes $250K – $3.5M checks · typically $1.5M

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Ask Shelley Zhuang to introduce you to Jacob

You →Shelley · together at Cannage Capital (2024–2026) →Jacob

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You →Jamie · 2 people · together at Delineate →Jacob

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You →Sam · together at Olli Health →Jacob

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About

Jacob Smith's biochemistry, EMT and MBA background drives a science- and patient-grounded focus on early-stage healthcare, biology and sustainability, shaped by a Midwest-to-San-Francisco career that launched a healthcare fund.

Invests in

AI & Machine LearningCybersecurityDeep TechHardwareHealthtechRobotics

Experience

  1. Cannage CapitalPartnercurrent2024 — presentSan Francisco Bay Area
  2. CancerNavigatorLead Investor & Board Observercurrent2025 — present
  3. DelineateLead Investorcurrent2025 — present
  4. BluePond AILead Investor & Board Observercurrent2024 — present
  5. Olli HealthLead Investor & Board Membercurrent2024 — present
  6. ottobooks AILead Investor & Board Observercurrent2024 — present
  7. NOETIKInvestorcurrent2022 — present
  8. ArborInvestorcurrent2021 — present
  9. uMedInvestorcurrent2020 — present
  10. MatchwellInvestor & Board Member (Acquired by Medical Solutions)current2021 — present
  11. 11.2 CapitalPrincipalcurrent2020 — presentSan Francisco Bay Area
  12. 30VenturesVenture Advisor2020 — 2023
  13. 30VenturesPrincipal2018 — 2020Madison, Wisconsin Area
  14. University of Wisconsin-MadisonConsultant at Business and Entrepreneurship Clinic2017 — 2018Madison, Wisconsin Area
  15. Lewis & Clark VenturesMBA Summer Associate2017St. Louis, MO
  16. gener8torAssociate2015 — 2016
  17. University of Wisconsin-MadisonScientific Researcher - Thesis2013 — 2014Madison, WI
  18. University of Wisconsin-MadisonResearch Assistant2013Madison, WI

Skills & more

Strategic Planning18Negotiation12Public Speaking13Venture Capital9Start-ups10Financial Analysis10Business Development10Research15Budgets10Healthcare1Sales10Entrepreneurship4
+6 moreCustomer ServiceTeachingPrivate Equity FundingMicrosoft OfficeMicrosoft ExcelMicrosoft Word

From Jacob's professional profile.

Deals · 8

Olli HealthSolo GP

via Cannage Capital · filed Nov 2025

Ginkgo BioworksSolo GP

via Cannage Capital

Hinge HealthSolo GP

via Cannage Capital

SardineSolo GP

via Cannage Capital

CovariantSolo GP

via Cannage Capital

Cruise AutomationSolo GP

via Cannage Capital

ForterSolo GP

via Cannage Capital

HumanSolo GP

via Cannage Capital

Attribution from SEC filings, press coverage, and firm rosters. Some rows are inferred. Not right? Tell us.

Other disclosed investments

Investor

Arbor EnergyMatchwell

Per curated public sources.

Colleagues at Cannage Capital

Qian Zhuang
General Partner at Cannage Capital
Shelley Zhuang
Founder and Managing Partner at 11.2 Capital

Frequently asked questions

Who is Jacob Smith?
Jacob Smith's biochemistry, EMT and MBA background drives a science- and patient-grounded focus on early-stage healthcare, biology and sustainability, shaped by a Midwest-to-San-Francisco career that launched a healthcare fund.
Where does Jacob Smith work?
Jacob Smith is Partner at Cannage Capital.
What does Jacob Smith invest in?
Jacob Smith invests in AI & Machine Learning, Cybersecurity, Deep Tech, Hardware, Healthtech, Robotics.
What check size does Jacob Smith write?
Jacob Smith typically writes checks of $250K – $3.5M.
What companies has Jacob Smith invested in?
Investments tracked here include Arbor Energy, Matchwell, Olli Health.
Where did Jacob Smith go to school?
Jacob Smith studied at University of Wisconsin-Madison (Master of Business Administration (M.B.A.), Corporate Finance); University of Wisconsin-Madison (Bachelor's Degree, Biochemistry and Cert. Global Health); Madison Area Technical College (Emergency Medical Technician (EMT)).

Same school

Shared employers