South Loop Ventures — Full Portfolio

CircNova uses artificial intelligence to generate, analyze, and identify circular RNA structures for therapeutic development.

AI & Machine LearningBiotechDetroit, US

Crystal Brown(Chief Executive Officer)inAlex Wesselhoeft(Principal Scientific Architect)inJoe Deangelo(Chief Scientific Officer)inRobin Pearce(Principal AI Architect)in

Co-investors100Km Ventures LlcID VenturesMichigan RiseService Provider Capital

Empromptu is an enterprise AI application platform that helps founders and product teams at regulated companies build and ship production-ready AI features—such as document processing, customer chatbots, and AI-powered CRMs—that integrate into existing SaaS platforms.

AI & Machine LearningEnterprise SoftwareSaaS

Co-investorsFoundersEdgeRogue Womens Fund

LunchTable is an advocacy marketing platform that activates employees, customers, and fans to create content and referrals, then attributes each resulting click, lead, appointment, and sale to the individual advocate.

AI & Machine LearningHR TechMarketing TechSaaSSports TechCincinnati, US

Joshua Reid(Founder)in

Co-investorsJumpstart VenturesTechstarsBlack Tech Nation VenturesCintrifuse CapitalPlug and Play Ventures

A music platform offering exclusive music collections that users can access after signing in or signing up.

ConsumerMedia & Entertainment

LISNR is an ultrasonic proximity platform that enables contactless commerce and customer engagement through presence detection, secure authentication, targeted promotions, and gamified loyalty experiences across retail, finance, mobility, and education sectors.

AdTechDeveloper ToolsEnterprise SoftwareRetail TechCincinnati, US

Rodney Williams(Founder & CEO)inChris Ridenour(Director)

BoardNick MacShane(Director)Monique Idlett(Director)Michael Venerable(Director)

Co-investors7BC Venture CapitalCincyTechCollectivCourtside VenturesJumpstart VenturesLeadX Capital Partners+11 more

Lokum provides staffing solutions within healthcare using technology.

B2B MarketplacesHealthtechHR TechHouston, US

Co-investorsTechstarsJP Morgan Chase

Milkbox is a creative agency offering brand strategy, design, and development services to help clients build brands and craft audience experiences.

Marketing Tech

Houston, US

Berkley Kristina Johnson Luck(Executive Officer, Director)Pedro Rossi Silva(Executive Officer, Director)

BoardZachary Ellis Jr.(Director)

Co-investorsAggie Angel NetworkBand of AngelsHouston Angel Network

PraxisPro is an AI-powered learning platform designed for pharmaceutical and life sciences commercial teams, offering interactive roleplay scenarios, compliance training, and performance tracking tools for sales representatives, trainers, and compliance leaders.

AI & Machine LearningHealthtechSaaSHouston, US

Cameron Badger(Executive Officer, Director, Promoter)

BoardBenjamin Alouf(Director)Omar Njie(Director)in

Co-investorsAlleyCorpTechstars

Smart Bricks provides analytical intelligence and advisory services to institutional real estate investors to support their investment decision-making.

AI & Machine LearningData & InfrastructureFintechPropTechDubai, AE

MohamedinMohamed Mohamedin

Co-investorsTechstarsNVIDIA500 GlobalCornerstone VCDuke Capital PartnersA16Z Speedrun+2 more

SmartWiz offers Wizzy, an AI-powered browser extension for tax professionals that extracts and organizes client documents (W-2s, 1099s, receipts, organizers) and fills tax returns directly in the user's tax software.

AI & Machine LearningFintechSaaS

Co-investorsSerac Ventures

Upgrade Boutique sells custom wigs and hair products including bundles, closures, and frontals through an online marketplace for stylists and consumers.

AI & Machine LearningB2B MarketplacesConsumerE-commerceMarketplacesHouston, US

Co-investorsTechstarsUrban Capital Network