OpenAI Startup Fund — 2025 Investments

Adaptive Security provides security awareness training, phishing attack simulation, and email security solutions designed to defend against AI-powered attacks, deepfakes, and social engineering threats.

CybersecurityEnterprise SoftwareNew York, US

BLBrian Long(Founder)inAJAndrew Jones(Founder)inBrian Long Andrew Jones(Founder)

Co-investorsABAbstract VenturesANAndreessen HorowitzENEniac VenturesK5K5 GlobalNVNVIDIASCScribble Ventures+7 more

Ambience is an AI platform that captures clinical encounters in real time, generates documentation, and suggests coding for healthcare providers across 200+ specialties.

AI & Machine LearningDigital HealthHealthtechSan Francisco, US

MNMichael Ng(Founder)inNBNikhil Buduma(Founder)inMNMike Ng(Founder)inMike(Founder)Nikhil(Founder)Nikhil Buduma Mike Ng(Founder)

Co-investors50500 GlobalAIAirTree VenturesAIAIX VenturesANAndreessen HorowitzAVavraCOCollective Liquidity+10 more

Develops edible, natural coatings and feed additives to extend the shelf life of perishable foods such as fish, seafood, meat, fruits and vegetables, and to improve poultry and aquaculture farm productivity.

BiotechCircular EconomyFoodTechNew Materials

Co-investorsADADB VenturesIMImpact Ventures Management Pty LtdFOFounders FundLULux Capital

Capital 49 is a venture capital firm investing in fintech, AI infrastructure, and SaaS companies globally.

AI & Machine LearningEnterprise SoftwareFintechSaaS

JZJack Zhang(CEO and co-founder of Airwallex)inChrisPhilipp

Co-investorsRARadar VenturesABAbstract VenturesATAthletic VenturesBABattery VenturesBEBenchmarkEMEmergence Capital Partners+6 more

Endex builds custom AI models integrated into Excel for financial workflows, offering cell-reference tracing, repeatable templates, data extraction from financial documents, and cited outputs from internal and external sources.

AI & Machine LearningEnterprise SoftwareFintech

Kevin Yang(Founder)Pratham Soni(Founder)Tarun Amasa(Founder)Tarun Amasa Kevin Yang(Founder)

Co-investorsDODorm RoomSOSoma Capital

Endex provides a platform for retail investors to create custom portfolios, research securities, and discuss trading strategies on a unified interface.

Creator EconomyFintechSaaSSocial

Co-investorsQUQUBIC Labs

Kick is an AI-powered platform that automates bookkeeping and accounting tasks for small business owners.

AI & Machine LearningFintechSaaS

CWConrad Wadowski(Founder)inAdrian Slipko(Founder)Conrad Wadowski Adrian Slipko(Founder)

Co-investorsFEFelicis VenturesGEGeneral CatalystGTGTMfundLILigature VCNENextwave [X] PartnersPIPID Fund I, a series of DV Collective, LP+10 more

Speak is an AI-powered language learning app that acts as a speaking-focused language tutor for individual learners.

AI & Machine LearningConsumerEdTechSocialSan Francisco, US

AHAndrew Hsu(Co-founder/CTO)inConnor Zwick(Founder/CEO)Colton Gyulay(Data \u0026 NLP Engineer)inAbbie Clifford(Recruiter)Maricel Lomonico(Lead Recruiter)MLMichael Lam(Product)in

Co-investorsACAccelANAngel Collective Opportunity FundCOCollaborative FundFIFirebolt Ventures Management Company, LlcGSGSV VenturesKHKhosla Ventures+22 more

Valthos develops AI systems to identify biological threats and design medical countermeasures in real time for biodefense applications.

AI & Machine LearningBiotechDefense TechNew York, US

Kathleen McMahon(Founder)inTess van Stekelenburg(Founder)

BoardTVTess Van Stekelenburg(Director)in

Co-investorsLULux CapitalFOFounders Fund

Worktrace enables teams to build and deploy AI agents with zero setup required.

AI & Machine LearningEnterprise SoftwareSan Francisco, US

DVDeepak Vasisht(CEO, Co-founder)inAJAngela Jiang(President, Co-founder)in

Co-investors8V8VCILIllinois VenturesCOConvictionGEGenius VenturesSESequoia CapitalSVSV Angel+1 more