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Macroscopic Ventures

Foundation

Seed · 15 people tracked

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Investment thesis

Macroscopic Ventures funds projects and people aiming to build a future guided by reason and compassion. Most of its funding stems from proactive research rather than inbound proposals. For grants it evaluates a project's theory of change and expected cost-effectiveness; for investments it looks at market opportunity and business plan. Across both, it weighs evidence that applicants can execute well and clear relevance to its focus areas, with particular interest in those who have thought carefully about the effects of AI developments. It also advises large donors and collaborates with aligned foundations and philanthropists.

Source: firm website, verified Oct 5, 2026.

Stage
Seed
Instruments
Equity · Grants
Founded
2019
Last 12 months
2 investments
Tracked investments
3

Team · 15 people

from the firm's website & public directories
Ruairí Donnelly· Co-founder, President

Provides oversight of leadership and strategy; also a board member of the Center for AI Safety.

Will Aldred· Grants Associate

Works on grant evaluations and grantmaking strategy, with a background in technological forecasting.

What they invest in

from 3 of 3 portfolio companies

AI & Machine Learning ×3Deep Tech ×2Enterprise Software ×2Data & Infrastructure ×1Developer Tools ×1

HQs:United States×1

Investments · 3 tracked

founders shown can be your intro path
Inherentinherentlaboratories.comJun 2026

Inherent is an AI research lab, incorporated as a Public Benefit Corporation, developing general-purpose inventive AI systems and "AI Scientist" agents intended to accelerate research and power autonomous labs.

AI & Machine LearningDeep TechEnterprise Software

Tantum Collinsin

Co-investorsIndex VenturesRadical VenturesEx/AnteMetaplanetMythos Ventures Management, LlcPropel Bio Partners

Inherentinherentlabs.aiJun 2026

Inherent develops general-purpose AI agents designed to augment scientific research and discovery across disciplines.

AI & Machine LearningDeep Tech

Louis Kirsch(Founder)inTantum Collins(Founder)inEdward Hughes(Founder)Kaloyan Aleksiev(Founder)

Co-investorsMythos Ventures Management, LlcEx/AnteIndex VenturesMetaplanetPropel Bio PartnersRadical Ventures

RunRLrunrl.comin𝕏Seed

RunRL offers a platform for improving machine learning models using reinforcement learning.

AI & Machine LearningData & InfrastructureDeveloper ToolsEnterprise SoftwareSan Francisco, US

Andrew Gritsevskiy(Founder)inDerik Kauffman

Co-investorsBlast.ClubNoxo CapitalPioneerY CombinatorEurasianhub VenturesMetsu Capital

Portfolio news

latest coverage across their companies

Frequently asked questions

What stage does Macroscopic Ventures invest at?
Macroscopic Ventures invests at the Seed stage.
What sectors does Macroscopic Ventures focus on?
Macroscopic Ventures focuses on AI & Machine Learning, Enterprise Software, Impact & Social Good.

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