/Investor DB

Long Game — 2025 Investments

2 investments dated 2025 · listed companies and verified rows first · show all

Cirrus Therapeuticscirrustx.cominAug 2025

Cirrus Therapeutics is a biotech developing gene and cell therapies based on ocular immunology to treat dry age-related macular degeneration (AMD), including an AAV gene therapy to restore the IRAK-M immune regulator and a next-generation retinal pigment epithelium (RPE) cell therapy for advanced geographic atrophy.

BiotechHealthtechLongevityCambridge, US

Ying Kai Chan(Co-founder & CEO)inAndrew Dick(Director, Promoter)

BoardAlexandra Cantley(Director)inKhoo Shih(Director)

Co-investorsClavystBioZAKA VCPolaris Partners

Syntaxsyntax-bio.cominDec 2025

Syntax Bio develops a discovery platform that accelerates stem cell-derived therapies by using its proprietary Cellgorithm technology to control and direct cell differentiation.

BiotechDeep TechMedical DevicesChicago, US

Ryan Clarke(Co-Founder, Chief Scientific Officer)inNiko Balanis, PhD(Co-Founder, Chief Technology Officer)inBrad Merrill, PhD(Co-Founder, Head of Innovation)Matt MacDougall, MD, PhD(Scientific Cofounder, Immunology Physician, Stanford University)inPatrick Shaddow(Executive Officer, Director)John Craighead, PhD(Chief Executive Officer)

Co-investorsAstellas Venture Management LLCDCVC (Data Collective)DCVC BioDraper AssociatesIllumina VenturesPortal Innovations+1 more

Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.