Wellness & Fitness Startups

Phitherapeutics (brand Phyla) develops patented bacteriophage-based skincare that targets acne-causing C. acnes bacteria while preserving the skin barrier and microbiome. Its phage treatment is marketed to consumers and recommended by licensed dermatologists and skin professionals.

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Pickle at the Palms is a pickleball facility and community in Seattle that offers court access, coaching, and member experiences centered around the sport of pickleball. The venue provides lessons, tournaments, and social events for players at all skill levels.

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Pickle Athletics is a social club in the East Bay that provides pickleball courts, fitness, and dining to members and the local community. The facility emphasizes competition, wellness, and social connection through sport.

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The Pickleball Club LWR operates an indoor pickleball facility offering staffed and extended-hours court access, with players reserving courts and PIN-code entry through Court Reserve. It serves recreational pickleball players of all ages, including supervised youth.

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The Pickleball Club of Georgia (PCGA) is a premium pickleball facility offering cushioned courts, Pilates studio, golf simulators, café and bar, and community programming such as leagues, clinics, and junior academies. Located in West Midtown, Atlanta, it targets recreational and competitive players of all levels and plans to open in early 2026.

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POLICANE produces non-centrifuged sugarcane sugar in crystal and syrup form that retains the cane's nutrients, vitamins, minerals, antioxidants and policosanols. It is marketed as a natural sweetener and nutritional food product with claimed health benefits related to cholesterol and blood lipid levels.

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Predictive Fitness builds data-driven products that turn training and performance data into insights and applications for improving health and fitness, including endurance-training tools such as TriDot and RunDot. Its products focus on optimized training and race execution for athletes.

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PAVA is a management platform and alliance for medical aesthetics and vitality practices, providing affiliated partner clinics with shared resources such as recruiting, training, IT, marketing, CRM, finance, and analytics support. It operates a network of partner aesthetic and cosmetic surgery practices across several U.S. states.

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Premier Weight Loss is a physician-led medical weight loss clinic offering GLP-1 therapy, obesity medicine, nutrition counseling, and patient support through a team of physicians, nurse practitioners, and clinical staff. It serves patients in the Indianapolis area with locations in Indianapolis and Fishers.

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Primal Health makes consumable oral care products that use its patented SMMRT Science, combining microbiology and molecular nutrition to balance the oral microbiome in both people and pets. Its products are sold direct-to-consumer and are backed by clinical studies on gum health and harmful bacteria reduction.

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Prime Women (PRiME) is an online lifestyle magazine for women in their 50s, 60s, and 70s, publishing articles on fashion, travel, fitness, beauty, finances, relationships, entertainment, and career advice. It targets an older female audience with content written by women in the same demographic.

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Probiotic Holdings is an institutional developer of probiotic and biochemical technology applications, identifying and developing technologies for commercialization. The company operates through its subsidiary SCD Probiotics, which develops and markets probiotic products for health and environmental applications.

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Protein2o produces protein-infused water drinks that combine whey protein isolate with electrolytes for hydration, marketed as a low-calorie post-workout and daily protein option. It targets athletes and fitness-focused consumers seeking muscle recovery and protein intake without high sugar.

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Protekt makes liquid dietary supplements sold in single-serve stickpacks that mix into water, with products targeting hydration, energy, sleep/recovery, and immunity. It markets to athletes and performance-focused consumers and manufactures its products in the United States.

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Pure Spectrum makes THC-free, hemp-based CBD wellness products for people and pets, sourcing hemp from organic farms and publishing batch test results for purity and potency. Founded in 2015 and based in Evergreen, Colorado, it sells direct to consumers and operated an early branded CBD retail store.

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Quelliv offers non-invasive low-level laser therapy treatments for pain relief, inflammation reduction, and skin health enhancement. The company targets consumers seeking alternative wellness solutions without downtime or side effects.

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Recess is a family-focused hospitality venue that provides supervised play spaces and dining experiences for young children and their parents. The business combines childcare supervision with food and beverage services to help families relax and connect.

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Retain Health builds software that guides individuals to adopt brain-healthy habits through personalized, evidence-based recommendations aimed at reducing the risk of Alzheimer's disease. Its non-invasive tools focus on behavior change and prevention education, designed to scale across broad populations.

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REV Gum makes sugar-free chewing gum formulated with caffeine and electrolytes as an alternative to conventional caffeine products, avoiding sugar, corn syrup, and additives. The company sells its gum directly to consumers.

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REVIV3 Procare develops clinically-tested hair care products using a proprietary Shielded Micro Technology formula to prevent thinning, breakage, and hair loss and promote healthier hair growth. Originally sold to salon professionals in Italy and the United States, the products are now available for direct consumer purchase.

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Rezilir Health is a precision medicine clinic offering brain health, longevity, and complex chronic condition care, including therapies such as hyperbaric oxygen, IV infusions, ketamine, neurofeedback, and genetic testing. It serves patients with neurodegenerative disease, autoimmune disorders, dementia, and environmental illnesses from its Hollywood, Florida location.

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Right On Brands develops, markets, and invests in health and wellness food and beverage products for health-conscious consumers, using industrial hemp, cannabis, adaptogenic superfoods, and natural water. Its brands include ENDO Brands, Humbly Hemp, ENDO Labs, and ENDO Dispensaries & Wellness.

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Rocky Mountain High Brands (RMHB) is a publicly traded beverage company that makes clean-label energy drinks with ingredients like hempseed, guarana, and ginseng, plus a line of electrolyte hydration drinks (ElectroSport/Electro Sportlyte). Its products target athletes, gamers, and active consumers seeking functional beverages.

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Rythmia operates a medically licensed 7-day retreat in Guanacaste, Costa Rica that uses ayahuasca plant medicine alongside workshops, spirituality, and medical supervision as a wellness and life-advancement program. It serves individuals seeking personal transformation and healing from conditions such as depression.

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