Nonprofit Startups

Chariot builds financial infrastructure for donor-advised fund (DAF) giving, connecting donors, nonprofits, and platforms to enable faster, verified charitable donations and payouts. The company serves nonprofits, individual donors, and DAF providers seeking to streamline and expand charitable giving.

6 investors

Charityvest offers a donor-advised fund platform for individuals and corporations to make tax-efficient charitable contributions in multiple asset types, invest those balances for growth, and distribute grants to charities. The service consolidates tax documentation while providing access to over a million nonprofit organizations.

3 investors

Darsel provides a personalized learning chatbot that teaches mathematics to students in low-resource settings through simple, text-based channels like SMS, WhatsApp, and Facebook Messenger. The platform is designed for K-12 school systems and operates as a nonprofit, partnering with governments and schools to supplement classroom instruction with data-driven insights for teachers.

3 investors

New Story is a nonprofit addressing the global housing crisis by funding and building homes across Latin America. It has also launched a venture capital fund focused on early-stage construction and housing innovations.

3 investors

Our World in Data is an open-access, open-source publication that presents research and interactive data visualizations on global issues such as poverty, disease, hunger, climate change, and inequality. It summarizes scientific literature across hundreds of topics and is provided for free as a public good for a general global audience.

3 investors

One Degree is a nonprofit that operates a web and mobile platform helping low-income individuals and families find, manage, and review nonprofit and government services such as healthcare, food banks, and employment assistance. It serves help-seekers and the case managers and social workers who support them, primarily in the San Francisco Bay Area and Los Angeles County, California, and Gainesville, Florida.

2 investors

OpenBiome Foundation advances microbiome-targeted therapies for serious conditions like Clostridioides difficile through partnerships, innovation funding, and open-access research tools. The organization works to expand patient access to microbiome treatments while accelerating scientific discovery in the field.

2 investors

80,000 Hours provides career research, an online guide, and one-on-one advice and introductions to help graduates choose careers that have a large positive social impact. It serves talented graduates seeking high-impact career paths.

1 investor

The ACLU is a nonprofit, nonpartisan organization that defends individual rights and civil liberties guaranteed by the U.S. Constitution, handling roughly 6,000 court cases a year through litigation, legislative advocacy, and community work. It focuses on First Amendment rights, equal protection, due process, and privacy, and works to extend rights to historically marginalized groups across the United States.

1 investor

Bayes Impact is a tech nonprofit that builds data-driven technology to address public interest problems and improve public services. It applies algorithms and data analysis to deliver large-scale social impact.

1 investor

CareMessage is a nonprofit social enterprise that runs a patient engagement platform delivering personalized health education and care coordination to low-income and underserved populations via text messaging. It partners with Federally Qualified Health Centers, Free and Charitable Clinics, and Tribal Health Organizations across the United States to improve health equity.

1 investor

Degrees of Freedom operates a blended higher education program combining in-person, online, and virtual reality instruction from established faculty, priced at the level of a Pell Grant.

1 investor

Democracy Earth builds free and open-source, censorship-resistant software to deploy digital democracies over the internet. Its work includes governance infrastructure for crypto networks, shadow referendums for activists, and the first Quadratic Voting implementation in the USA for the Colorado Legislative House.

1 investor

Dost Education is an ed-tech nonprofit that delivers early childhood development resources to under-resourced parents and caregivers through parent education, helping them prepare children for school. It operates in India, reaching families through partnerships with state governments.

1 investor

Giveffect offers an all-in-one SaaS platform built for nonprofits, covering fundraising, events, online donations, volunteer management, donor management, marketing, and constituent relationship management. It consolidates these nonprofit operations into a single software product.

1 investor

GiveSpark was a celebrity-driven charity fundraising platform. The company operated in the nonprofit fundraising space.

1 investor

mRelief is a nonprofit that operates a web and text-messaging platform (via shortcode 74544) to help Americans check their likely eligibility for SNAP benefits and sign up. It uses USDA public datasets on BBCE and COVID-19 Waivers and covers all 50 states and DC.

1 investor

New Incentives runs conditional cash transfer programs that encourage mothers in Nigeria to have their infants immunized against preventable diseases. It operates as a nonprofit focused on public health in Nigeria.

1 investor

Recidiviz is a non-profit technology company that builds an open-source platform to ingest, link, and standardize criminal justice data from across data silos, making it usable for government agencies, researchers, advocates, and policymakers. Its products and analyses help justice systems track progress, inform evidence-based policy, and support the reentry of justice-impacted individuals.

1 investor

SIRUM is a nonprofit that uses technology to redirect unused medicine from institutional sources to safety-net clinics, helping underserved patients access needed prescriptions. It also offers consulting and technical assistance to county governments, community clinics, and drug donor groups to set up prescription drug redistribution programs.

1 investor

Tarjimly built a mobile application and language-access software combining AI and human volunteer translators to connect refugees and limited-English speakers with interpreters in healthcare, legal, and social services settings. The nonprofit was acquired by CLEAR Global in 2025.

1 investor

The Centre for Effective Altruism promotes effective altruism, applying evidence and reasoning to help people decide which causes to support and how to use their money or time to do the most good.

1 investor

UPchieve provides free, online tutoring and college counseling to low-income middle and high school students across the United States through a volunteer-powered model. The platform matches students with live coaches in under 5 minutes across 20+ subjects including math, science, humanities, and test preparation.

1 investor

Upsolve is a nonprofit that helps low-income Americans overcome debt and rebuild credit, operating a financial education website and a free DIY bankruptcy filing tool. It is expanding into AI tools to help people resolve financial distress earlier.

1 investor