Neurotechnology Startups

Mindstate Design Labs is a clinical-stage drug development company that uses AI to map the biological basis of emotion and cognition, synthesizing psychedelic phenomenology and biochemical data to design pharmaceutical compounds that induce specific therapeutic emotional and cognitive states for mental health treatment.

12 investors

Piramidal bridges in-vivo and in-silico intelligence for neuroscience research and clinical applications. The company develops technology that integrates biological data with computational intelligence.

8 investors

BIOS Health develops neural interfaces to read and apply nerve data for medical use, applying AI to precision medicine for the nervous system. Formerly known as Cambridge Bio-Augmentation Systems (CBAS), it initially focused on prosthetic neural interfaces.

7 investors

BrainKey is an AI-driven digital healthcare company focused on brain longevity and dementia prevention. It applies AI to brain health analysis in the neurotechnology and digital health space.

5 investors

Craniometrix provides AI-powered care navigation and support services to help dementia patients remain at home while reducing hospitalizations for their families and caregivers.

5 investors

An AI research organization that develops interface innovations and neural technologies, focusing on human-AI interaction breakthroughs including neural signal processing and thought decoding methods.

4 investors

Rain Neuromorphics develops neuromorphic AI processors built as physical artificial neural networks using electroceramic materials, nanofabrication, and biologically inspired learning models. Its chips aim to support continuous, low-power on-device AI learning as an alternative to GPU/CPU-based neural network simulation.

4 investors

Nectome offers a whole-body and whole-brain human preservation method intended to retain every synapse and cell at end of life for potential future revival. The protocol is compatible with traditional funerals at room temperature and remains stable for hundreds of years when stored cold.

3 investors

Parasma develops algorithms and infrastructure to train living neural systems for computation, aiming to make advanced AI far more energy-efficient and accessible by leveraging biological neurons as programmable compute. The company serves organizations seeking to reduce the energy footprint and hardware costs of AI systems.

3 investors

Well Principled builds BODYSIM, a fitness forecasting system that uses "digital twin" technology combining sensor fusion with metabolic and physiological science to model body composition, energy expenditure, and hormone balance. The company's core technology translates academic research into simulations, with applications spanning consumer fitness and enterprise models of consumer behavior and battery electrochemistry.

3 investors

Actipulse Neuroscience develops non-invasive brain stimulation technologies using high-frequency magnetic pulses to treat central nervous system disorders, including major depressive disorder and neurodegenerative diseases. The company conducts clinical research on transcranial neuromodulation devices.

2 investors

Auricle develops a neurostimulation implant designed to restore hearing for patients who do not benefit from hearing aids or existing solutions.

2 investors

Exin Therapeutics develops an AI-guided drug discovery platform that uses experimental mouse studies to identify neurological therapies, starting with epilepsies linked to autism and Parkinson's disease. The company trains machine learning models on proprietary multimodal neuroscience data to guide its therapeutic screening process.

2 investors

Circumvent is a pharmaceutical and biotech company that studies monogenic disorders to inform the development of treatments for complex diseases. It applies genomics and neurotechnology approaches to drug discovery.

1 investor

Dydema builds AI models that interpret brain signals for brain–computer interface applications, and records brain-signal datasets to train those models. It targets developers and organizations building neurotech products.

1 investor

Prophecy Sciences builds a suite of cognitive tests that combine behavioral measures with biosignal sensors to quantify factors such as mental aptitude, personality, and decision-making styles. It uses this neuroscience-based data to help employers hire the right candidates and help managers optimize and motivate their teams.

1 investor

SpringWit is a neurotechnology company focused on brain health and awareness.

1 investor

Torpedo Therapeutics develops high-precision, closed-loop deep brain stimulation devices for treating neurological disorders including Parkinson's disease, essential tremor, dystonia, and drug-resistant epilepsy. The company uses micro- and nano-fabrication to create ultra-small electrode leads with machine learning-driven parameter adjustment to reduce side effects and improve treatment efficacy.

1 investor

Voyage Biomedical develops medical device technology that uses cooling to prevent brain damage during stroke. The company was acquired by Penumbra (NYSE:PEN).

1 investor