Mental Health Startups

Sensible Care connects clients with licensed therapists and psychiatrists, offering insurance-based, often same-week appointments through a secure app to book sessions and track progress. It serves individuals in the U.S. seeking mental health care covered by major insurance providers.

1 investor

Serenatis Bio develops small-molecule drugs targeting glutamate and dopamine pathways to treat obsessive-compulsive disorder, a mental health condition with limited effective therapeutic options. The company's pipeline includes three novel candidates designed to work faster and with fewer side effects than existing medications.

1 investor

Sero Mental Health operates a nationwide network of treatment centers providing mental health care to individuals with mental health conditions and co-occurring diagnoses. The company serves patients through direct care, provider partnerships, and career opportunities for mental health professionals.

1 investor

Sessions Health is an all-in-one, HIPAA-compliant electronic health record (EHR) platform designed by therapists for mental health practices of all sizes. It combines scheduling, documentation, billing, a client portal, telehealth, and reporting into a single system for therapists and billers.

1 investor

Shmoody is a mobile app for self-care and mental health that guides users to take real-world mood-improving actions through an intentionally fun, science-backed experience. It also offers Shmoody U, a version for colleges and universities to support students.

1 investor

Shmoody is a mobile app that combines mental health support with accessible, engaging tools designed to encourage users to take actionable steps toward improved wellbeing. The platform targets students and college populations by making mental health tools feel relatable and enjoyable rather than clinical.

1 investor

Sholder provides one-to-one transformational mental wellness sessions through trained community providers who use active listening and reflective questioning to help individuals reconnect with their inner wisdom. The service offers an alternative approach to traditional counseling and coaching, targeting people seeking mental well-being support.

1 investor

Sift News Therapy addresses news-related anxiety and stress, aiming to help people engage with difficult topics in a way that supports deeper understanding and civic engagement in the U.S.

1 investor

Siggy offers clinician-supervised, always-on AI therapy that combines daily check-ins, medication management, and goal tracking, with licensed psychiatrists reviewing and prescribing non-controlled psychiatric medications. The service serves individuals seeking mental health care and is available to U.S. residents, rolling out state by state.

1 investor

Six Wing Studios is a game studio developing The Fog of Maya series and Amaru: The Self-care Virtual Pet, games designed to introduce players to mindfulness and meditation. It funds and delivers its titles and merchandise to fans through crowdfunding campaigns.

1 investor

Skylyte offers a digital "navigator" that measures and improves team health and resilience, using a diagnostic-led approach to baseline team wellbeing, surface actionable data, and support team action-planning with coaching and nudges. It targets workplace teams and managers to reduce burnout and churn, positioned in the mental health and future-of-work space.

1 investor

Ash is a mental health platform that provides digital therapy and support services. The company operates in the mental health and behavioral health sector.

1 investor

Sobrynth provides employers with a workplace benefit that delivers 24/7 care navigation and peer coaching for employees and families navigating substance use, recovery, and sober curiosity. The platform addresses a gap in employee mental health support by reducing stigma and offering dedicated resources for those on any path toward sobriety.

1 investor

SocialRx connects members with community-based activities like art, culture, nature, and movement to address mental health and loneliness. The company provides a social prescribing solution that bridges gaps in traditional mental health services, particularly for underserved populations.

1 investor

SoFiiT offers a wellness platform that combines physical movement, social engagement, and AI-driven data insights to improve users' physical activity and mental wellness. A case study cites improved activity levels and mental wellness among USC Viterbi Engineering students.

1 investor

Sojorne provides digital care coordination, expert guidance, and community support for families managing autism care, from diagnosis through therapy. The platform integrates AI-powered navigation tools, a communication app, and access to multidisciplinary pediatric therapy services.

1 investor

Sokya Health (operating as Headlight) provides mental health care including talk therapy, medication management/psychiatry, and Spravato (esketamine) sessions. Services are offered to individuals seeking mental health treatment, delivered in-person or virtually.

1 investor

Sophy Health develops multimodal AI agents for wellness platforms, mental health apps, and coaching services. The AI companions provide empathetic support, track behavioral patterns, and integrate across voice and chat channels.

1 investor

Soula is an AI companion app built specifically for women that provides emotional support and self-regulation tools, remembering a user's story, cycle, and moods to give personalized responses. It addresses stress, anxiety, sleep, life transitions, fertility worries, and relationship strain, drawing on techniques informed by neurology.

1 investor

SoundSelf is a voice-activated biofeedback therapy system that translates a patient's breath and voice into light, sound, and vibration to guide them into calm, meditative states. It is used by therapists and clinicians as a complement to psychotherapy, ketamine, and Spravato treatments to support patient regulation and integration.

1 investor

Southern Pediatrics is a healthcare organization that operates a network of clinics providing pediatric and behavioral health care, combining pediatricians and behavioral health experts to focus on preventative care. It targets children in resource-limited areas, aiming to expand access to comprehensive pediatric care regardless of geographic location or socioeconomic status.

1 investor

Southwest Youth & Family Services is a nonprofit offering free and low-cost resources and services to youth and families across Southwest King County, including family resource access, youth advocacy, early learning, GED/high school education, mental health counseling, and after-school support. It works to close gaps in access to education, mental health care, and basic resources.

1 investor

Speek offers a digital, DBT-informed recovery programme for families of young people who self-harm, providing chat and group sessions with UK clinicians, guided content, and a peer support community. It serves parents and families, delivering behavioural and emotional tools and connecting them with specialists to support self-harm recovery.

1 investor

Oops LOVE offers online telemedicine for men's health conditions such as ED and AGA (hair loss), with consultations and prescriptions handled through LINE. The service is aimed at consumers in Japan.

1 investor