Mental Health Startups

Mindstep is a digital mental health platform that provides assessments, self-guided care, live therapy, and real-time insights to organisations for supporting employee mental health. Founded by doctors, its tools are validated in peer-reviewed studies and regulated as a medical device, covering areas such as stress, burnout, ADHD, and cognitive health.

2 investors

Lief is an AI wearable that measures heart rate and breathing to track stress in real time via heart rate variability (HRV), and guides users through HRV biofeedback exercises to self-regulate their stress response. It offers a drug-free approach to managing stress and worry, supported by clinical psychologists, therapists, and health coaches, with optional live chat and video coaching sessions.

2 investors

LifeSpeak is a SaaS-based holistic wellbeing platform that provides expert-led mental, physical, and family health resources through microlearning videos, live expert sessions, fitness content, and caregiving tools. It serves employers, health plans, and organizations, offering a product suite that includes mental health, parenting/caregiving, wellness, fitness, and substance-use solutions.

2 investors

Lionheart is a venture capital firm with a team of investors, serial entrepreneurs, and domain experts who invest across AI, psychedelics, neurotech, and human flourishing sectors.

2 investors

Lumenate offers a smartphone app and a light mask called Nova that use precise flickering light sequences to synchronise brainwaves and guide users into meditative, semi-psychedelic states. It targets consumers seeking improved mental wellbeing through guided journeys for exploration, relaxation, and sleep.

2 investors

Kinder World is a free mobile game designed to promote kindness and positivity. The company creates gaming content for a broad audience with the goal of making the world a kinder place.

2 investors

Luna Family Autism provides fully virtual, parent-led ABA (Applied Behavior Analysis) therapy for families of children with autism, with programs designed and directed by Master's and PhD-level Board Certified Behavior Analysts. The service is delivered via telehealth to families in several U.S. states, focusing on flexible, family-centered care with reduced weekly time commitment.

2 investors

Lupa Run offers personal audio running coaching that guides users during their runs, combining training courses (from 0 to 10k+) with meditation, breathing, and mindfulness practices. It provides a subscription app with pacing tools for iOS and Apple Watch, aimed at runners seeking both physical improvement and mental wellbeing.

2 investors

Magic Story creates personalized hardcover children's books that feature the child as the protagonist, addressing emotional themes like patience and growth. The books are designed for parents and grandparents seeking to reinforce learning and resilience through personalized storytelling.

2 investors

Magnus Medical develops SAINT, an FDA-cleared, accelerated form of TMS (transcranial magnetic stimulation) therapy that uses precision neuromodulation to treat Major Depressive Disorder, including treatment-resistant depression, over a 5-day course. The noninvasive, non-drug treatment was developed at Stanford's Brain Stimulation Lab and is delivered to patients through verified clinical providers.

2 investors

Matter develops a consumer iOS app that helps users track positive emotions and brain activity to improve subjective well-being. The company partners with academic institutions to identify biomarkers for happiness and mental health.

2 investors

MEandMine offers an AI-powered platform that combines neuroscience and gamification to support student behavioral health and emotional regulation, using daily check-ins and 200+ games to help children self-regulate. It serves as a tool for schools, districts, and counselors, analyzing in-game behaviors to identify struggling students and support early intervention.

2 investors

Meomind provides personalized, evidence-based psychotherapy accessible on demand 24/7 through digital platforms. The company targets individuals seeking mental health support and aims to scale therapy access globally at affordable rates.

2 investors

Mindance offers a mental health app and health-insurance-covered online stress management courses, providing guided meditation, mindfulness exercises, sleep stories, and coaching for individuals, employees, and families. Based in Germany, it is a subsidiary of the work-life balance provider pme Familienservice Group.

2 investors

Mindframe builds AI-powered technology for behavioral health practitioners to enhance clinical care delivery and patient engagement in regulated healthcare environments. The platform is designed for mental health clinics, hospitals, and health systems.

2 investors

Mindler provides digital mental health care, offering online psychological treatment through a network of clinicians serving patients across multiple countries. It operates in the digital health and mental health sector.

2 investors

MindMate is a mobile app that supports caregivers and individuals with cognitive decline through brain games, nutrition guidance, exercise, and social interaction features. The app helps users document memories and maintain engagement while managing symptoms of dementia and Alzheimer's.

2 investors

Definium Therapeutics is a biotech company developing psychedelic-based treatments for brain health disorders, including formulations of LSD and MDMA enantiomers targeting depression, anxiety, PTSD, and autism spectrum disorder. Its pipeline focuses on psychiatric and neurological conditions affecting patients in the U.S.

2 investors

MiSalud Health provides accessible and affordable virtual healthcare services, combining professional clinicians with bilingual support to serve Latino and immigrant communities in the United States. The platform removes barriers of language, cost, and geography by connecting users with licensed healthcare providers including family medicine, mental health, and nutrition specialists.

2 investors

Monte Nido provides evidence-based residential and outpatient treatment programs for eating disorders and co-occurring conditions like PTSD, serving adolescents and adults. The organization conducts institutional review board-approved research to demonstrate treatment outcomes and inform continuous care improvements.

2 investors

Moovd offers WeMind, a tool for therapists that aims to reduce the duration of therapy sessions. The company provides its methodology with scientific backing, along with content such as blogs and articles.

2 investors

Neend is a sleep and relaxation app offering bedtime stories, yoga nidra, guided meditations, and calming music in Hindi, English, and regional Indian languages including Marathi, Tamil, and Telugu. It targets consumers seeking better sleep quality and relaxation.

2 investors

neurocare group operates a network of over 20 clinics across Europe, the United States, and Australia offering personalized mental health treatments such as TMS, neurofeedback, and tDCS for conditions including depression, ADHD, OCD, and sleep disorders. It also provides a Digital Therapy Platform and an online academy that trains third-party clinicians in its treatment protocols.

2 investors

Neurode develops a wearable neurostimulation headband paired with a companion app that provides personalized insights and recommendations from psychologists, neuroscientists, and engineers. The device uses clinical-grade stimulation pads and targets adults in the US managing mental health and neurological wellness.

2 investors