Medical Devices Startups

XMetix develops an automatic tourniquet device controlled by software that activates with a single button press, designed for rapid bleeding control in military and civilian emergency settings.

1 investor

XM Therapeutics develops extracellular matrix-based therapies to treat patients with chronic disorders, with initial applications targeting heart failure and pulmonary fibrosis. The company is based in Providence, Rhode Island and leverages partnerships with Brown University for research and development.

1 investor

A biotechnology company developing a peptide-based delivery platform that uses lipid raft targeting to transport therapeutic proteins into the cytosol of human cells with minimal lysosomal degradation. The technology is designed for pharmaceutical companies and researchers needing intracellular delivery of therapeutic macromolecules.

1 investor

Xpan develops a single universal trocar for minimally invasive surgery (MIS) that accommodates all surgical instruments, aiming to replace traditional trocar access. The device is intended for MIS surgeons and the surgical device market.

1 investor

XRlabs develops a surgical intelligence platform combining artificial intelligence and extended reality to provide 3D visualization and guidance for surgical planning, intraoperative procedures, and medical training. The platform converts standard medical scans into interactive digital twins for surgeons.

1 investor

Xsensio develops wearable biosensor systems that continuously monitor physiological parameters to detect health risks in real-time. The company aims to commercialize Lab-on-Skin technology for healthcare applications.

1 investor

Xtrac Medical develops a sheathless, vibration-based technology for extracting implanted cardiac leads with improved safety and procedural efficiency. The company serves electrophysiologists and medical institutions performing lead extraction procedures.

1 investor

X-trodes develops technology for collecting and analyzing electrophysiological data outside traditional medical facilities, enabling research, diagnosis, and treatment applications. The company serves researchers, clinicians, and healthcare institutions seeking portable electrophysiological monitoring solutions.

1 investor

Xyall operates in medical technology and molecular diagnostics, leveraging expertise in digital pathology and health innovation to scale diagnostic solutions.

1 investor

XYLYX develops transplantation technologies using regenerative medicine, bioengineering, and translational science to expand access to organ transplantation. The company works with surgeons, physicians, and regenerative medicine experts to advance tissue engineering and clinical innovation for transplant applications.

1 investor

Ybrain develops brain science-based technology solutions for mental health monitoring and improvement, using neuroscience, materials engineering, and computer science to help users monitor and maintain their brain health. The company serves the digital health and mental wellness market globally.

1 investor

Yewtwist makes a handheld tool with flexible rubber jaws in three sizes designed to disconnect IV line connections easily and without damaging the lines. It serves nurses and at-home patients who manage their own IV lines, and is designed and manufactured in Canada.

1 investor

Ykrita develops the EBDLR System, a bioengineered liver-assist device that supports blood purification and regeneration for patients with acute liver failure, offering an alternative to transplant surgery. The company focuses on innovative medical technologies to improve patient outcomes and make healthcare more accessible and effective.

1 investor

Y-mAbs develops radioimmunotherapy and antibody-based therapies targeting pediatric and adult cancers, with a heritage in high-risk neuroblastoma and expansion into additional oncology indications.

1 investor

YolTech Therapeutics develops in vivo gene editing medicines using a proprietary lipid nanoparticle delivery platform to treat genetic, metabolic, and autoimmune diseases. The company operates clinical-stage programs targeting conditions including Transthyretin Amyloidosis, Alpha-1 Antitrypsin Deficiency, Primary Hyperoxaluria, Beta Thalassemia/Sickle Cell Disease, and Familial Hypercholesterolemia.

1 investor

YorLabs develops an intracardiac echocardiography (ICE) ultrasound imaging system aimed at interventional cardiology and electrophysiology procedures. The system is designed for single-operator control with a zero-CapEx, zero-footprint approach to support image-guided therapy.

1 investor

Koalaa manufactures prosthetic sleeves for people with limb differences, offering customizable options matched to the wearer's condition and intended activities.

1 investor

Yseop provides an AI-powered platform that automates medical writing and regulatory reporting tasks for life sciences teams, accelerating document submission timelines within the CTD pyramid framework. The platform uses neuro-symbolic AI to transform complex documentation workflows and ensure compliance in pharmaceutical regulatory processes.

1 investor

Yunu offers a clinical trial imaging platform that harmonizes imaging workflows, data, and compliance from initial scan through trial submission, cutting turnaround times and reducing manual work. It serves sponsors, CROs, and cancer centers running oncology and other clinical trials, aligning radiology, oncology, and trial roles in a single system.

1 investor

Z-Loupes develops ergonomic dental loupes with features such as lighter weight, neck-mounted batteries, and handsfree controls for infection control. The products target dental, medical, veterinary, and esthetician professionals.

1 investor

Zaamigo AG operates the Kluvo brand, which offers a 3D dental camera for digital scanning, visualization, and treatment planning. The product is aimed at dental professionals and industry stakeholders.

1 investor

Zalvac develops innovative vaccines against bacterial infections using bacterial membrane vesicles as a platform, targeting pathogens like Streptococcus pneumoniae. The company is founded by leading microbiology researchers at Karolinska Institutet.

1 investor

ZAP Surgical develops the ZAP-X Gyroscopic Radiosurgery platform, a self-shielded surgical robotics system for non-invasive cranial stereotactic radiosurgery (SRS) that uses linear accelerator technology instead of radioactive sources. It serves neurosurgeons and radiation oncologists, aiming to make cranial SRS feasible in a wider range of clinical settings, including outpatient and rural locations.

1 investor

ZBeats is a cardiac technology company offering FDA-cleared electrocardiographic analysis software that transforms ECG signals into structured clinical intelligence for cardiology workflows. The platform serves healthcare organizations, remote patient monitoring providers, diagnostic testing facilities, and medical device manufacturers with arrhythmia detection and data integration capabilities.

1 investor