Medical Devices Startups

Omniose develops a platform for bioconjugate vaccine development using glycoconjugation technology to create vaccines against bacterial pathogens like Group B Streptococcus and Klebsiella pneumoniae. The company works with pharmaceutical and research partners to advance vaccine candidates through preclinical and clinical development.

1 investor

ONCALL operates a home medical care support service in Japan, providing night and holiday house-call teams plus an online "Connect" team that supports clinical decisions and links medical institutions and multidisciplinary staff nationwide. It aims to expand young physicians' involvement in home care and improve the quality and supply of home-based medical care, particularly end-of-life care.

1 investor

On the Right Track provides a patented hookless cubicle curtain track system, recyclable and textile curtains, in-person curtain changeout services, and a cloud-based QR-code tracking app for hospitals and healthcare facilities. Its products aim to reduce hospital-associated infections and improve compliance and operational efficiency for regional hospitals, healthcare networks, surgery centers, and similar facilities.

1 investor

Oncobit provides molecular diagnostic solutions that enable clinicians to monitor cancer and optimize therapy selection through advanced genetic analysis of plasma samples.

1 investor

Oncobox provides genetic profiling of tumor samples to help oncologists select the most likely effective drug from existing targeted cancer therapies for individual patients with advanced cancer. The analysis examines tumor DNA, RNA, and molecular pathways to identify the most relevant drug targets and generates a clinical report recommending which treatments are most likely to work.

1 investor

Oncoclínicas operates a network of over 140 units — clinics, genomics and pathology laboratories, and integrated cancer treatment centers — across 40 Brazilian cities. It provides cancer diagnosis and treatment services for patients in Brazil.

1 investor

OncoForma develops a functional precision oncology platform that tests patient-derived tumor organoids against comprehensive drug panels to predict treatment efficacy before therapy begins. The company serves oncologists and cancer patients in the global oncology market, operating from Saskatchewan with a pathway to scale from fee-for-service testing to AI-enabled predictive medicine.

1 investor

OncoLux develops an optical theranostic system that gives surgeons intraoperative enhanced visualization of residual cancer and combines it with optical photodynamic therapy to treat remaining tumor tissue during surgery. The technology targets cancer surgery patients and clinicians in the medical device field.

1 investor

OncoNano Medicine develops a proprietary nanotechnology platform for cancer therapeutics that targets the acidic tumor microenvironment to improve drug delivery to tumors. The company serves oncology patients and builds a pipeline of therapies designed for more precise cancer treatment.

1 investor

OncoRevive develops a multiomics blood test combining nanotechnology, cancer biology, and AI to detect and monitor cancer in less than 2 hours at a fraction of current costs. The test is designed for healthcare providers, hospitals, and pathology labs seeking rapid, comprehensive same-day cancer diagnostics.

1 investor

Oncostellae is a biotech company developing novel JAK inhibitors for the treatment of inflammatory bowel disease and cancer, with a focus on local, gut-restricted therapies that minimize systemic toxicity.

1 investor

OncoSwab develops a nasal swab-based sampling platform that captures airway-derived genetic material to detect ctDNA and cancer-associated biomarkers at the origin of lung cancer, complementing blood-based liquid biopsy. It is offered as a Research Use Only tool for researchers running lung cancer biomarker, longitudinal, and multi-site studies while clinical validation is underway.

1 investor

Oncosyne develops functional biology tools and preclinical models for cancer drug development and patient stratification, serving oncology drug developers and precision medicine researchers.

1 investor

Oncoxome develops an oral delivery platform for cancer therapies that targets tumor cells directly with minimal off-target toxicity. The platform enables delivery of various therapeutic modalities including CRISPR, siRNA, mRNA, and proteins to cancer patients.

1 investor

OncRef provides structured oncology intelligence—a database and query layer aggregating clinical trials, drugs, mechanisms, approvals, guidelines, and key opinion leaders—for oncology professionals and life-science teams seeking current, unified information across the cancer field.

1 investor

Oncura provides veterinary ultrasound systems designed for use by general practice teams, with real-time remote guidance from sonographers and internal medicine specialists. The platform includes a portable ultrasound device and secure telehealth portal to enable quick diagnosis of common conditions without requiring on-site specialist expertise.

1 investor

Ondal Medical Systems manufactures suspension arm systems designed for safe and ergonomic handling of medical devices in clinical environments. The company serves medical technology providers and healthcare facilities globally with suspension solutions that improve workflow efficiency.

1 investor

OneBreath is an international medical device company that commercializes mechanical ventilation technology developed at Stanford University, offering high-performance ventilators at an affordable cost. It focuses on advancing critical care in emerging countries with products designed for those environments.

1 investor

One Physics offers medical physics consulting services, including diagnostic and health physics, radiation therapy physics, dosimetry treatment planning, and radiation safety officer support. It serves healthcare facilities across the US with a focus on local, relationship-driven service.

1 investor

A biotechnology company focused on developing therapeutics related to genetic regulation of longevity and aging processes, with expertise in drug development and clinical trials.

1 investor

OneKind develops AI-driven computer vision software that converts behavioral video data into validated clinical endpoints for animal health studies, beginning with pruritus detection in canine and feline dermatology trials. The platform replaces subjective manual observation with automated, frame-level behavioral measurement to improve statistical rigor and reduce measurement variability in veterinary clinical research.

1 investor

One Health Group develops AI-driven diagnostic and monitoring platforms serving the medical technology sector across both animal and human health applications. The company leverages proprietary physiological datasets and sensing technologies to create differentiated medtech solutions.

1 investor

OneOncology invests in and partners with community oncology practices to deliver cancer care, helping them grow, diversify across specialties, and apply data and technology to improve performance. It operates a network of oncology and urology practices across the United States.

1 investor

OneRoom Health builds a clinical-grade immersive care environment that brings patients, providers, diagnostics, and data into a single space to deliver in-person-quality care across distance. It serves health systems and patients in rural and underserved areas seeking to expand care access without additional travel, facilities, or staff.

1 investor