Longevity Startups
430 companies tagged Longevity, with their investors and founders.
Next Health operates wellness clinics offering IV vitamin therapy, NAD+ drips, peptide therapy, and bioidentical hormone optimization delivered through in-lounge sessions and membership plans. It serves consumers focused on longevity and health optimization, with locations in cities including West Hollywood, Century City, Studio City, New York City, Nashville, and Maui.
2 investors
Nitrase Therapeutics is a clinical-stage biopharmaceutical company using its NITROME platform to develop therapeutics based on nitrases, a class of enzymes it discovered that drive protein nitration. Its lead program is an antibody targeting the pathogenic form of alpha-synuclein in Parkinson's disease, with a pipeline aimed at neurodegenerative, cancer, fibrotic, respiratory, and autoimmune diseases.
2 investors
NovalGen is a clinical-stage biotechnology company developing multi-specific biologic immunotherapies using its AutoRegulation platform technology, which adds self-regulating capabilities to drugs for safer treatment. Its pipeline targets oncology, autoimmune, haematological, and metabolic disorders.
2 investors
NuSirt Sciences develops therapies that activate the sirtuin pathway by combining established pharmaceuticals and natural products to treat cardiometabolic conditions of aging and overnutrition, including fatty liver disease (MAFLD/MASH), obesity, type 2 diabetes, and hypertension. Its lead drug candidate TRIPLN combines L-leucine, metformin, and sildenafil, and it also markets LEUSIX, a dietary supplement for cardiometabolic health and weight management.
2 investors
Phycin develops engineered growth factors designed for higher stability and performance, including a thermostable recombinant basic fibroblast growth factor (bFGF) that remains active for 21+ days at 37Β°C. Its products target researchers and clinicians working in regenerative medicine, cell culture, and related life science applications.
2 investors
Previvor Edge offers a multidisciplinary cancer prevention and early-detection program that combines genetic testing, clinical risk assessment, lifestyle guidance, and screening tools such as multi-cancer tests and full-body MRIs. It serves individuals at elevated cancer risk, including those with a family history, and works with multiple insurance plans as well as self-pay options.
2 investors
Rona Therapeutics develops siRNA-based therapeutics using its GAIA platform to target metabolic and cardiovascular conditions including hypertriglyceridemia, obesity, ASCVD, and MASH. Its pipeline includes APOC3, INHBE, PCSK9-Lp(a), and angiotensinogen-targeting candidates for patients with cardiovascular and metabolic diseases.
2 investors
Samsara Therapeutics develops small-molecule therapeutics that activate autophagy to slow the progression of age-related neurodegenerative diseases such as ALS, Parkinson's, and Charcot-Marie-Tooth disease. It runs an in-house phenotypic screening platform using patient-derived iPSCs to identify and validate autophagy activators for drug discovery.
2 investors
SanegeneBio is a biotech company developing RNA interference (RNAi) genetic medicines for obesity, cardiometabolic, and autoimmune diseases. Its LEAD (Ligand and Enhancer Assisted Delivery) platform enables tissue-specific gene silencing in the liver, adipose tissue, muscle, and immune cells via subcutaneous dosing.
2 investors
Sorrento Therapeutics is a biotechnology and life sciences company that develops therapeutics and technologies through in-house programs, acquisitions, and mergers. Its portfolio spans areas including antibody-drug conjugates, cell therapy, and lymphatic drug delivery systems.
2 investors
Seraphina Therapeutics develops food- and nature-based consumer health products, starting with the fatty acid C15:0 (pentadecanoic acid), aimed at replenishing micronutrients and metabolites that decline with age. The company focuses on evidence-based nutritional science for consumer wellness.
2 investors
Tally Health offers longevity products including epigenetic aging tests (the TallyAge cheek swab), science-formulated supplements, and personalized DNA-based insights for consumers seeking to slow aging. It sells these direct-to-consumer through individual products and a membership that combines testing, monthly supplements, and action plans.
2 investors
The Akkermansia Company develops postbiotic supplements built around a pasteurized form of the gut bacterium Akkermansia muciniphila (Akkermansia MucT), sold direct to consumers to support gut barrier integrity, weight management, and overall wellness. Its products, such as Healthy Weight, combine the strain with ingredients like EGCG green tea and chromium.
2 investors
The Lanby is a membership-based medical practice combining primary care, functional medicine, and longevity services delivered by a multidisciplinary care team (physician, dietitian, nurse practitioner, and member advocate) under a single plan. It serves individual patients seeking proactive, preventive healthcare and is based in New York City.
2 investors
The Swell is a membership community focused on women's health and longevity in midlife, offering conversations, masterclasses, and courses with experts on topics such as menopause, hormone therapy, brain health, sexual wellness, and emotional well-being. It serves women navigating perimenopause and midlife through expert-led programming and community access.
2 investors
Thymmune Therapeutics develops a machine learning-driven thymic cell engineering platform that mass-produces iPSC-derived thymic cells to restore immune function affected by aging and disease. The company is building a pipeline of off-the-shelf cell therapies for immunodeficiencies, transplant-related, and autoimmune disorders.
2 investors
Tisento Therapeutics is a biopharmaceutical company developing zagociguat, an investigational oral, once-daily brain-penetrant soluble guanylate cyclase (sGC) stimulator, as a treatment for MELAS, a mitochondrial disease affecting multiple organ systems. Its work targets patients living with MELAS and other severe diseases that lack effective treatment options.
2 investors
Uncommon Therapeutics uses advanced technologies to develop drugs targeting rare genetic diseases, starting with Rett Syndrome, a neurodevelopmental disorder affecting approximately 1 in 10,000 girls. The company combines disease expertise with efficient drug development to advance therapeutics from discovery to clinical application.
2 investors
Cogent Biosciences is a biotechnology company developing small molecule precision therapies for genetically driven diseases where the cause is linked to a specific genetic mutation. It runs a discovery organization in Boulder, Colorado, aiming to create treatments for patients with unmet medical needs.
2 investors
Vivo offers live, small-group fitness classes led by certified trainers over Zoom, combining strength training with cognitive exercises for older adults who work out from home. Each session is adapted to the participant's level and physical limitations, with support from a care team of trainers, nutritionists, and older adult specialists.
2 investors
VO Health is developing a blood test based on multi-omics molecular signatures to measure biomarkers related to human healthspan, performance, adaptation, and recovery. Founded by physician-scientists, it partners with performance establishments, clinics, clubs, and universities and operates a CLIA laboratory and proprietary biobank.
2 investors
Wave Life Sciences develops RNA-targeting therapeutics using RNA-editing modalities and chemistry to treat rare and common diseases, with a clinical pipeline addressing Alpha-1 antitrypsin deficiency, Duchenne muscular dystrophy, Huntington's disease, and obesity. It operates in the biotech and RNA medicines industry.
2 investors
Yuva Biosciences uses an AI platform called MitoNova to discover compounds that improve mitochondrial health and address aging-related cellular decline. Its discovered compounds, such as Y100, are used in consumer products including Revive+ by BosleyMD for hair.
2 investors
Famitra operates a marketing and consulting service focused on family trusts (civil trusts) in Japan. The company helps individuals and families resolve financial planning issues through trust-related advisory services.
2 investors