Longevity Startups

Response Pharmaceuticals is a clinical-stage drug developer working on RDX-002, a small-molecule iMTP inhibitor for weight management and metabolic health, including post-GLP-1 receptor agonist weight management and antipsychotic-induced weight gain. The company is advancing the candidate through Phase 2 clinical trials.

1 investor

Restore operates a network of wellness studios offering cryotherapy and other science-backed recovery therapies for athletes and fitness enthusiasts. The company has expanded from a single Austin location to over 115 franchised locations across multiple states.

1 investor

Reverse Infinity is a health clinic and bio-hacking lab in Goa offering therapies such as medical-grade Hyperbaric Oxygen Therapy (HBOT), red light therapy, cryotherapy, and IV therapy. It serves people seeking recovery, anti-aging benefits, and performance optimization, including athletes and wellness enthusiasts.

1 investor

Revision Skincare offers skincare products marketed as part of an ABC E Skin Longevity Regimen. The page provides ingredient information for multiple serums, correcting complexes, and creams.

1 investor

Ribogenyx develops first-in-class therapeutic enhancers of translational fidelity, targeting mRNA translation processes for precision medicine. Its focus is on age-related diseases and mechanisms of stress resilience mediated by mRNA translation.

1 investor

A website publishing research posts on pharmacological compounds, covering topics such as receptor antagonists, kinase inhibitors, and drug mechanisms in various disease models. The content focuses on biomedical and life-sciences research summaries.

1 investor

The Roskamp Institute conducts scientific research to develop therapies for neurological and neuropsychiatric conditions and to support healthy aging, running clinical studies and trials focused on brain health for its local community. It also offers a doctoral degree program in Neuroscience with laboratory-based research training.

1 investor

SafeinHome provides remote support services and assistive technologies to enable people with intellectual and developmental disabilities and aging adults to live independently in their homes and communities. The company offers 24/7 remote support specialists and person-centered care solutions tailored to individual needs.

1 investor

Sanford Burnham Prebys is a nonprofit biomedical research institute that conducts basic and translational research across cancer, cardiovascular/muscular, neurologic, and metabolic/liver diseases, supported by centers for therapeutics discovery and data science/AI. It also operates a graduate school and post-doctoral training programs and offers technology licensing and partnership opportunities to translate discoveries into treatments.

1 investor

Savoy Life addresses fragmentation in senior care coordination by helping families, caregivers, and primary care providers manage care across disconnected providers. The company serves seniors and their care networks to reduce preventable hospitalizations, ER visits, and caregiver burnout.

1 investor

Scancell is a UK clinical-stage biotechnology company developing off-the-shelf active immunotherapies for cancer using its Immunobody and Moditope platforms, with a lead melanoma product (iSCIB1+) and a solid-tumour candidate (Modi-1). Through its subsidiary Glymab Therapeutics, it is also developing GlyMab and AvidiMab antibody technologies targeting tumour-specific glycans for solid cancers.

1 investor

Scarlet Therapeutics develops a platform that produces lab-grown, universal red blood cell-based therapeutics (tRBCs) engineered to carry high levels of therapeutic proteins for treating a range of diseases. It initially targets rare metabolic diseases such as hyperammonemia and hyperoxaluria, with potential applications in other metabolic diseases, cancer, and autoimmune conditions.

1 investor

SciRouter develops science-led daily supplements for humans, dogs and cats, with formulas that list active ingredients and doses tied to published research. It targets consumers interested in longevity and healthy aging for themselves and their pets.

1 investor

InsideTracker provides personalized health analytics and recommendations based on blood tests, DNA analysis, and lifestyle data. The company serves consumers seeking to optimize their health, nutrition, and longevity through science-backed, customized guidance.

1 investor

Senesys.Bio develops NanoJAGGs, a nanostructure-based delivery platform that targets and eliminates senescent cells to treat age-related and chronic diseases. The nanostructures selectively localize to senescent cells and can be configured to carry a range of therapeutic molecules, including senolytics, antioxidants, small drugs, and biomolecules.

1 investor

Senior Helpers provides in-home senior care across the United States, offering services from companion assistance with daily activities to specialized care for chronic conditions. It serves seniors and their families, including those with Alzheimer's, dementia, and Parkinson's disease.

1 investor

Senior Service provides non-medical home care and supplementary informal-care support for elderly people in the Netherlands, ranging from weekly companionship to 24-hour care, helping seniors continue living at home. It matches clients with fixed employed caregivers and coordinators, and advises on financing routes such as insurance, PGB, Wlz and Wmo.

1 investor

Senior Sign provides software to streamline the move-in process for senior living communities. The platform is designed to modernize administrative workflows and improve the resident experience during onboarding.

1 investor

Senotherapeutix (d/b/a Gerotherapeutix) develops gerotherapeutics based on its MitoXcel geropeptide platform, which targets mitochondrial mechanisms of cellular aging to improve healthspan and extend lifespan. The company operates three subsidiaries spanning longevity therapeutics (Eos Senolytix), oncology peptides (Perseus Senolytix), and controllable gene therapies (Phoenix Senolytix).

1 investor

SeraGene Therapeutics is a pre-clinical stage biotech company developing RNA (siRNA) and nanomedicine-based therapies for coagulation disorders, including rare bleeding disorders, platelet dysfunction, and thrombotic disorders. It aims to provide long-lasting, low-burden prophylactic treatments for patients living with chronic coagulation conditions.

1 investor

SilverEco is a French online news and information portal covering the "silver economy" and healthy ageing, publishing articles on topics such as seniors, caregivers, nursing homes and senior housing. It also organizes the SilverEco Bien-Vieillir festival and a series of industry congresses bringing together operators, startups and investors in the ageing sector.

1 investor

Skylark Bio develops precision-targeted, locally delivered AAV gene therapies for single-gene disorders, starting with genetic causes of hearing loss and extending toward central nervous system conditions. Spun out of research at Harvard Medical School and Massachusetts General Hospital, the company builds a gene therapy platform aimed at durable benefit from a single treatment for patients with genetically defined diseases.

1 investor

A healthcare-focused organization that applies P4 medicine principles—predictive, preventive, personalized, and participatory care—leveraging data analytics and tailored treatment approaches for patients and healthcare payors. The company works with academic, corporate, and venture capital partners to deliver value across the healthcare ecosystem.

1 investor

Spark Health is a healthcare practice offering personalized primary care that combines conventional and natural medicine. It provides individualized assessments, diagnostic testing, and holistic treatment plans aimed at identifying root causes of health conditions and supporting long-term wellness and longevity.

1 investor