Longevity Startups

Ora Biomedical is a longevity-science company that developed an AI and robotics platform for high-throughput screening of aging interventions using C. elegans research tools. Spun out of the University of Washington longevity-science community, it works on healthy-aging and regenerative medicine research.

1 investor

Orion Biotechnology is a biotech company developing GPCR-targeted therapeutics for obesity and metabolic disorders, with preclinical candidates against targets including GPR75, GIPR, and amylin. It operates a proprietary drug discovery platform designed to shorten GPCR discovery campaigns and pursues out-licensing and R&D collaborations.

1 investor

Oroi provides virtual reality applications that deliver entertainment and cognitive stimulation for older adults, aiming to support emotional wellbeing and train cognitive functions. Used with VR headsets, its content includes 360° panoramic landscapes, cognitive training exercises, and pedal-based physical activity, and is used in care homes and home care (SAD) services.

1 investor

Pelagos Pharma develops drugs targeting hard-to-treat receptors for age-related diseases, with a focus on extending healthspan and longevity.

1 investor

Perlara is a biotech company that runs early-stage drug R&D programs for rare diseases, partnering with patient families, companies and impact investors to screen gene-edited patient avatars for repurposable drugs. It has launched drug repurposing trials at Mayo Clinic for rare conditions such as PMM2-CDG and NGLY1-CDDG.

1 investor

Perseus SENOLYTIX is a gerotherapeutics company developing senolytic peptides to target senescent cells and restore cellular balance in aging organisms. The company focuses on translating scientific discoveries into therapeutics addressing fundamental mechanisms of aging.

1 investor

PPHC is a concierge primary care medical practice offering personalized, patient-centered medicine including preventive care, chronic disease management, diagnostics, and wellness services. Based near Wellesley in Greater Boston, Massachusetts, it serves patients seeking direct access to board-certified physicians and coordinated specialist care.

1 investor

Phoenix SENOLYTIX develops gene therapies targeting senescent cells to address aging-related conditions. The company utilizes its ApoptiCIDe-CE™ platform technology, validated in human patients, to eliminate unwanted cells in the body.

1 investor

Pihlakodu operates modern nursing and care homes in Estonia, offering general care, round-the-clock nursing, home care, dementia care, and physiotherapy services. It serves elderly people and adults needing assisted living, with locations including Kristiine, Tartu, and an upcoming facility in Ülemiste City.

1 investor

Ponce Aurora develops mitochondrial-targeting longevity products including a full-body treatment and energy beverages powered by MitoXcel™ technology, which addresses age-related decline in mitochondrial function. The company serves the consumer longevity and wellness market with information-based gerotherapeutics.

1 investor

Ponce Aurora is a longevity company developing cosmetics, beverages, and supplements that target aging-related cellular issues using proprietary geropeptide technology. The company's lead products include YUUTH™, a topical full-body treatment marketed for skin and body rejuvenation, and YUURN Boost™, a beverage designed to provide sustained energy without caffeine-like side effects.

1 investor

PRD Therapeutics is a drug-discovery startup developing first-in-class oral SOAT2-selective inhibitors (PRD compounds derived from pyripyropene A) to regulate lipid metabolism. Its lead program targets the rare disease homozygous familial hypercholesterolemia (HoFH), with planned expansion to MASH/MASLD and other lipid-metabolism disorders.

1 investor

Preamble provides proactive, personalized health management combining comprehensive diagnostics (100+ biomarker blood panels, DEXA body composition, cardiac and fitness assessments), physician-interpreted health reports, and long-term coaching to extend clients' healthspan and lifespan. It offers membership-based preventive care that complements primary care for individuals focused on longevity and optimizing their health.

1 investor

PreventiveMD is a telehealth service offering compounded and FDA-approved GLP-1s, peptides, and other targeted therapies for weight loss, recovery, and healthy aging, along with advanced lab testing and genetic risk screening. Patients complete an online assessment, have a U.S.-licensed provider review and prescribe, and receive ongoing physician-adjusted care through a portal for a flat monthly price without insurance.

1 investor

Pria offers a HIPAA-compliant technology platform that integrates health-at-home solutions for chronic care management, helping healthcare organizations deliver remote care at scale to patients and members. It focuses on the Medicare population, supporting aging in place and improving adherence to remote care management.

1 investor

Primus Senior Living develops senior citizen residential communities in India, designing homes with active-living and safety features such as motion-sensor lighting and incorporating Blue Zone principles and preventive wellness. It targets older adults seeking retirement living focused on healthspan alongside lifespan.

1 investor

ProBiotix Health develops probiotic formulations aimed at lifestyle conditions such as cardiometabolic health, backed by clinical trials conducted with UK universities and microbiology researchers. It collaborates with research institutes, universities, and hospitals across the UK and Europe to develop and validate its probiotic products.

1 investor

Proxima Health offers blood diagnostics to detect environmental toxins such as microplastics, PFAS, and heavy metals, alongside lifestyle protocols and blood filtration interventions to remove them. It targets consumers concerned about environmental toxin exposure in the health and wellness space.

1 investor

Pure MHC discovers HLA Class I and Class II peptide targets for immunotherapies targeting cancer, infectious disease, and autoimmune diseases using the sHLA platform technology.

1 investor

Qollabs (삶의질 연구소) builds accessible, AI-based digital solutions aimed at improving quality of life for elderly people, including tools for communication with adult children and healthy grocery shopping. Its current focus is an AI solution that digitizes senior-care housing services such as retirement communities (silver towns).

1 investor

Recall Therapeutics is a biotechnology company developing therapeutics that target biological pathways linking cognitive decline with systemic health, aiming to restore functions lost to disease and aging. Its research focuses on Alzheimer's disease, cancer-related cachexia, and age-related muscle loss.

1 investor

Refoxy is a science-driven company focused on drug discovery, medicinal chemistry, and bioinformatics. The team page emphasizes deep science and collaboration, but the page provides only placeholder text about the company's specific work.

1 investor

Remedy Place operates physical "Social Wellness Club" locations that combine alternative medicine, wellness technology, and hospitality, offering treatments such as guided ice-bath breathwork, saunas, hyperbaric chambers, lymphatic compression, IV vitamin and NAD therapy, acupuncture, functional medicine, and biometric testing. It positions itself as a membership-based category distinct from spas or gyms, pairing self-care with social connection.

1 investor

Rendever provides immersive virtual reality experiences for senior living residents designed to reduce social isolation and foster meaningful connections. The platform uses VR headsets to enable shared experiences like virtual travel, reminiscence therapy, and social activities tailored for older adults with cognitive or mobility challenges.

1 investor