Longevity Startups

CryoBios is a life-extension organization offering cryopreservation services using glucose-based stabilizers and cryo-capsules. It also uses AI data-mining to create a digital record of a client's life and personality, stored on an implanted cryptographically protected gold wafer, and offers an investment strategy to preserve clients' savings.

1 investor

CutisBio applies synthetic biology and biomanufacturing to develop microbial strains, biomaterials, and production processes for use in health, beauty, and fashion applications. It works with manufacturing and distribution partners to bring materials to market, with a stated focus on longevity and healthier lives.

1 investor

Cyclarity Therapeutics develops engineered cyclodextrin drugs that target and remove toxic oxidized cholesterol (7-ketocholesterol) to treat atherosclerosis and other age-related diseases. Its lead candidate, UDP-003, is a preclinical/early clinical therapy aimed at cardiovascular disease, with additional pipeline programs for stroke recovery, Alzheimer's, and other conditions.

1 investor

Dalton Bioanalytics develops comprehensive biochemical analysis of humans in a single test, aimed at advancing preventative healthcare.

1 investor

DELiver Therapeutics develops small molecule and peptide therapeutics using high-throughput DNA encoded library (DEL) drug screening to address challenging and previously "undruggable" targets in clinical medicine, with a focus on tyrosine kinase targets. Its R&D facilities are located at K2Bio in Houston.

1 investor

EADERM develops pharmaceuticals and therapeutics for hair loss and skin disorders based on tissue stem cell aging and regeneration control technology. The company targets treatment and prevention of alopecia and age-related skin conditions through innovative approaches centered on cellular mechanisms rather than symptomatic relief.

1 investor

Welloff operates senior living residences under the Eclasia brand, offering assisted living with no upfront entrance fee, on-site nursing care insurance services, and medical care support provided by visiting nursing staff. It serves elderly residents in Japan seeking housing with care and safety.

1 investor

EdenRoc Sciences is a life sciences holding company that founds and funds subsidiary biotechnology companies addressing diseases of aging, with assets spanning genomic detection, clinical-stage pharmaceuticals, forensics, and biologic-based consumer products. Its subsidiaries operate autonomously while sharing board oversight and centralized business functions, and its work spans diagnostics and therapeutics across biotech and healthcare markets.

1 investor

Elisabeth Holistic Eldercare Harmony Living operates a long-term residential eldercare and geriatric rehabilitation facility offering holistic care programs for senior citizens and their families. The unit, which opened in May 2023, includes an adjacent boutique hotel where relatives can stay.

1 investor

Eloxx Pharmaceuticals is a clinical-stage biopharmaceutical company developing small molecule therapeutics designed to address nonsense mutation genetic disorders. The company is advancing exaluren for rare kidney diseases including Alport syndrome and ADPKD through clinical trials.

1 investor

EmpowerMe Wellness delivers integrated healthcare services to senior living communities, including care coordination, on-site physical/occupational/speech therapy, pharmacy services, and dementia care through Medicare's GUIDE Model. It places dedicated clinical teams and virtual physicians and nurse practitioners on-site to support residents in assisted living and memory care communities across the US.

1 investor

Emtora Biosciences is a clinical-stage life science company developing eRapa, a novel formulation of rapamycin, to prevent the onset and recurrence of cancer. Its lead program, Serenta (eRapa), is in a Phase 3 trial evaluating safety and efficacy in patients diagnosed with familial adenomatous polyposis (FAP).

1 investor

Endless Health provides an all-in-one platform for wellness and longevity practitioners, combining precision lab testing, practice-management and clinical documentation software, and launch/strategy support. It serves preventive health and wellness professionals building or scaling their own coaching and clinical practices.

1 investor

Endolipid Therapeutics is a biotech developing SHBG-mimicking peptides aimed at reducing ectopic fat accumulation to treat conditions such as fatty liver disease and NASH, as well as cellulite. Its work spans therapeutic and dermocosmetic applications.

1 investor

Enlivex is a Nasdaq-listed clinical-stage biotech developing Allocetra, a macrophage reprogramming immunotherapy targeting age-related knee osteoarthritis to restore mobility and function in aging populations. The company also runs a treasury strategy anchored in RAIN, a prediction markets protocol on Arbitrum, offering public-market exposure to prediction market infrastructure.

1 investor

Enov.one is a telehealth service offering personalized longevity and hormone optimization care, including bio-identical hormone balancing (for optimization, peri- and post-menopause) and pharmaceutical-grade medications and supplements such as B12, NAD+, and GSH. It uses an online assessment and AI, optionally combined with lab or DNA results, to connect patients with board-certified doctors and address conditions like fatigue, brain fog, mood imbalances, and weight management, serving 48 of 50 US states.

1 investor

Eos SENOLYTIX develops senolytic peptides designed to restore cellular balance in aged or senescent cells across body organs, focusing on gerotherapeutics. The company targets age-related conditions through proprietary approaches to cellular rejuvenation.

1 investor

Eos BioInnovation invests in early-stage regenerative medicine therapies and technologies, focusing on cell, gene, and tissue therapies that target disease causes. The firm partners with researchers and entrepreneurs to accelerate the translation of breakthrough science into commercial biotech companies.

1 investor

EPOCA provides medical remote monitoring (télésurveillance) for seniors, including those with multiple unstable chronic conditions such as heart, respiratory, or renal failure and diabetes, to support safe care at home or in care facilities. Its approved medical device and dedicated care team enable 24/7 remote follow-up prescribed by physicians in France, aiming to reduce avoidable hospitalizations and readmissions.

1 investor

Eterna Care develops a mobile health monitoring system that tracks vital signs, location, and health data for seniors, enabling quick emergency response and allowing family members and care professionals to monitor elderly individuals remotely. The platform combines GPS and mobile communication to support independent living and chronic condition management.

1 investor

Eternygen is a Berlin-based pharmaceutical company founded in 2012 that researches and develops drugs for diet-related metabolic diseases such as fatty liver, diabetes, and obesity. Its work centers on the sodium-coupled citrate transporter NaCT as a therapeutic target to correct the underlying metabolic defect.

1 investor

Etiome develops stage-specific medicines by applying single-cell omics and artificial intelligence to map disease progression and identify disease-modifying targets at early biological inflection points for preemptive intervention. Founded in 2021 out of Flagship Pioneering's Preemptive Health and Medicine initiative, the biotech company focuses on treating or reversing disease before it advances to later stages.

1 investor

Find Therapeutics is a clinical-stage biopharmaceutical company developing therapies to treat demyelinating diseases, particularly multiple sclerosis and related conditions affecting myelin repair. The company was founded in 2020 and is based in Canada with backing from multiple life sciences investors.

1 investor

First Longevity operates a longevity-focused platform, including a daily newsletter covering longevity science, investment, and innovation, and DLT, a data system that tracks longevity companies, signals, and trends.

1 investor